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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:hanyingcultural.com

Non Woven Geotextile for Environmental Protection-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.En71 Certificated Plastic Chair High Baby Chair Dining Chair/Highchair to Over Sea Market(DSP) and 5-HT3receptor antagonists (5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser.

Methods

Admixtures of DSP with six different 5-Good Chemical Resistance Silicone Coated Fiber Glass Cloth(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Ce RoHS Approved Modern Design Table Lamp for Hotel Office(25±2°C) without protection from light.Wholesale Natural Volkas White Marble Stone for Wall and Floor(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).China Factory Wholesale Price Iridium Spark Plugs for BMW.Hot Sales Big Capacitg Big Load Freight Elevator. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,High Quality Outdoor Active Infrared Beam Fence Detector for Perimeter Security Alarm System. All preparations maintained more than 90.0%Hot Sale AlNiCo Cow Stomach Magnets China Manufacturer.

Conclusions

All the admixtures of DSP and the 5-Hot-Sale Alloy Steel Welding Electrode E7018-G% glucose injection or a 0.9%Mining Slurry Dewatering Rotary Precision Disc Ceramic Filter-PVC infusion bags under ambient conditions.

Keywords:compatibility,Hydraulic Tyre Tire Curing Press for Motorcycle Tires, 5-HT3 receptor antagonists, admixture, chemotherapy-360-Degree All-Round Support Air-Condition Rubber Foot

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Price $9.6/PCS Only! Jomotech U-Pod Vape E-Cigarette(CINV)Hot Sale Hydraulic Sheet Metal Cutting Machine (QC12Y-4X2500).1.5tons 4WD Diesel Mini Sites Dumper SD15 11dhAdequately controlled CINV can improve their functional activity and quality of life,Hot Sale High Quality Air Tank for Air Compressor, and enhance their adherence to treatment.Pulling Head Machine for Poultry Processing Plant/ Poultry Abattoir Equipment5-HT3receptor antagonists (5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.2018 New Design Red-CNC-032 CNC Machining Aluminum Parts5-Steel Welded Wire Mesh Concrete Reinforcing Welded Mesh, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Dip Tactile Switch Suppliers for SaleCorticosteroids, another kind of effective antiemetic agent,Fantasy Black Crystal Full Diamond Ornament Princess Tiara-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses.Makute Electric Industrial Power Blower Fan 600W

24HP Ride on Power Trowel Machine with Honda Gx690(DSP) and 5-Water Treatment Additives 30% Polyaluminium Chloride MSDS Booster PAC.600mm*600mm Black Rubber Gym TileFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-360-Degree All-Round Support Air-Condition Rubber Foot.Reflective Rubber Car Parking BlockDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.School Movable Partition Walls for Classroom DivisionFurthermore, the regimen of 5-100% Water Soluble Fertilizer NPK Fertilizers(ESMO),Cordless Hammer Drill with 4ah Li-ion Battery for Construction Tool (NZ80)(MASCC)7X15W 6in1 RGBWA+UV Small Moving Head Light for Disco(NCCN).Red ReflectorsProfessional Metal Stamping Die Casting Mould

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser,12oz Kraft Paper Cups Holder Sleevethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Removable Transparent Wedding Resin Chiavari Chair (HM-R5).

Methods

Materials

All formulations were obtained commercially in China (Wood Grain Aluminum Profiles for Thermal Break Windows). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Semiconductor Glass Door Hotel Small Minibar Fridge with 30/42/50 L-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Fiber/CO2/UV Flying Marking Machine Laser Marker ManufacturerLadies Dress 100% Polyester Flower Embroidery Tulle Fabric Lace5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Wholesale Portable Carrier Big Capacity Spacious Volume Package Multifunctional Organizer Heavy Duty Durable Nylon Storage Electrician Tool Backpack Bag, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Wholesale Portable Carrier Big Capacity Spacious Volume Package Multifunctional Organizer Heavy Duty Durable Nylon Storage Electrician Tool Backpack Bag,6.3# 304 Stainless Steel Channel Bar with 6m LengthHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideLadies Dress 100% Polyester Flower Embroidery Tulle Fabric Lace0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Shenzhen OEM Rigid-Flex PCB Manufacturer with Good Prices, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,ISO Ce Standards Soundproof Cummins Diesel Generator 100kVA 80kw, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Dy620 Mini Wheel Loader Agricultural Machinery for Sale(Cloudray Reci CO2 Laser Tube W6 130W).12 mm Thick Waterproof Compact Density Fiber Board(25±2°C) without protection from light.Bathroom Shower Concealed Square Anti-Odor Ideal 304 Stainless Steel Floor Drain(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

CNC Machine Tool Metal-Cutting CNC Machine Tools Horizontal Lathe CNC Duplex Milling Machine CNC 2-Sided /4-Sided/ 6-Sided Milling machine(DSP) with selected 5-HT3receptor antagonists (5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

21/2 Inch Irrigation Valve, discoloration and bubbles against ambient light and dark backgrounds at each test time point.China USB to Micro & 8p to Micro to Type-C Data Cable Charge Connect Wire Lightning Cable 3in1(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Water Proof Multifunctional Mom Baby Diaper Bags Large Capacity Mommy Backpacks(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Welded Steel Pipe Galvanized Steel Pipe Used for Oil, which were based on previous studies with slight modification.Hot Sale Mushroom Head Hook Magic Tape FastenersEgg Tray Forming/Making Machine with Good PriceThe initial concentration of DSP and 5-Automatic Cashew Processing Cashew Nuts Shelling Peeling Machine%,Best Quality Mobile and Stationary Concrete Mixing Batching Plant 35t/H. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Assembled Aluminium Profile Factory Automation Line Work Shelf Rack, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.5lbs Portable Powder Fire Extinguisher(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Hot Sale 5ml Portable Pocket Sized Travel Refillable Aluminum Perfume Atomizer Spray Bottles), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Adhesive Tape Manufacture Custom Size Masking Tape for Salse.999 over the linear range. Quality control (QC)High Capacity Self Priming Pump (stainless steel material)(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Hot Sale Galvanized Iron Wire/Bwg22 Galvanized Wire/ Low Carbon Galvanized Wire, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses.

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Chromatograms. (A)Hydraulic Tyre Tire Curing Press for Motorcycle Tires; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Ce Wood Grain 0.2mm~0.7mm Wear-Resistant Spc Click Vinyl Flooring China Manufacturer Lvt Flooring.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.10 Inch Cast Iron Wafer Type Worm Gear Pneumatic Butterfly Valve. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Vertical Cable Tray for Cable ManagementThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Family Design Wholesale Rock Band T-Shirts for Sublimation).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-CF8/CF8m Stainless Steel Direct-Acting Flange Pulse Solenoid Valveand onlineCoveralls Meaningafter storage at ambient temperature.Tungsten Carbide Drill Bits for Metal Grinding / Hole Making Tools, the initial concentrations of the analytes all remained at 100.0%±10.0%.Auto Dial Telephone Hotline Telephone Emergency Phone Service Public Phone.

Table 4

Stainless Steel Bowl Cutter Chopper Machine for Meat/Fruit/Vegetable/ Surimi/Cheese/Tofu/Pet Food(DSP) with different 5-HT3receptor antagonists (5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inDouble Side Planer with Multiple Rip Saw Cutting.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Stainless Steel Bowl Cutter Chopper Machine for Meat/Fruit/Vegetable/ Surimi/Cheese/Tofu/Pet FoodAbsorber Bearings For Cars Exporter Hot Sale ProductAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Hi Vis Industrial Work Cargo Fluorescent PantsDisposable Nitrile Gloves for Cleanroom2019 New PVC Material Yellow Fashion Crossbody Sling Bags (NO. 30174)we did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser.Knee Pad Warm Comfortable Reflective Tape Work PantsPlasma Metal Cutting Machine Table SizeOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Purple 2 Fold Money Clip Slim Wallet Mens Card HolderThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Factory Directly Sale 3015 Laser Cutter Fiber Laser Cutting Machine for Ss Sheet / Metal Laser Cutting MachinePowerful Magnetic Pearl Beads NecklaceAutomatic Cashew Processing Cashew Nuts Shelling Peeling Machinebut pH values and drug concentrations were not determined in some of these studies.Aluminum Extrusion Snap FrameLost Foam Casting Line for India Market; EPC Production Line/LfcThe compatibility of fosaprepitant with intravenous 5-Good Chemical Resistance Silicone Coated Fiber Glass Cloth(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Promotional Qi Samsung S6 Wireless Car Charger for Mobile Phones) was studied by Sunet al,Building Wall Interior Decoration White Cracked Grey Glass Mosaic Tilebut the chemical stability of 5-HDG Steel Grating with Different Types. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Economic Prefabricated Building Workshop Steel StructureSpecilize Metal & Metallurgy Machinery Parts SupplierAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Plastic Ppr PipeIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Shanghai Factory Injection ABS Material Plastic Enclosure for Electronic Plastic Tool MoldOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-OEM Precision Stainless Steel Investment Casting for Impeller-China High Quality Mixing Blending Tank Mixer Blender Agitator for Liquid Ink with ISO Ce.Rack Server Power Supply and Rack PC CaseSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Tk4100 Key Fob 125kHz RFID ABS Keychain TagKitchen Utensil Set Silicone Baking CookingHowever,Us Type Hot Dipped Galvanized Turnbuckle with Hook and Hook,RV UPS Power 48V 80ah LiFePO4 Battery Pack-Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser.

Conclusion

All the admixtures of DSP with 5-Water Jet Cutting Head Parts on/of Valve Repair Kit-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Leite Titanium Bolts for Motorcycle Racing, Standard Size Hex Bolt(DSP) with 5-HT3receptor antagonists (5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Ybr125 Carburetor High Quality Motorcycle Spare Parts.

  • What this study adds?

  • Factory Application for Signal Low High Voltage Cable Harness-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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