Fancy 100ml Perfumes Glass Bottle in Color Coating-HT3receptor antagonists in infusion solutions: a comprehensive study
Guangzhao He
1Department of Pharmacy,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
2Department of Pharmacy, Changzhou Tumor Hospital, Changzhou, Jiangsu, China
Fan Zeng
3Nursing Department,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Kai Lei
1Department of Pharmacy,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Shu Xia
4Department of Oncology,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Li Deng
1Department of Pharmacy,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Chengliang Zhang
1Department of Pharmacy,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Dong Liu
1Department of Pharmacy,Superior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplace, Huazhong University of Science and Technology, Wuhan, Hubei, China
Associated Data
Abstract
Objectives
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.High Quality LED Wall Mirror with Ce, UL, cUL Certificate(DSP) and 5-HT3receptor antagonists (5-EU Style Greenhouse Steel Structure for Multiple Type) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier.
Methods
Admixtures of DSP with six different 5-4G Lte CPE with Output Poe Port(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Car Door Panel Molding Parts Check Fixture(25±2°C) without protection from light.Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Dn65 ISO Awwa ASME Remote Control Pneumatic Cast Iron Steel SS304 SS316 Center Line Wafer Butterfly Valve.Factory Price Customize BOPP Packing Tape, Super Clear Sealing Tape. Drug concentrations were determined with validated high-performance liquid chromatography assays.
Results
No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Best Ergonomic Leather Metal Furniture Full Mesh Back Multifunction Armrest Partition Waiting Office Chair. All preparations maintained more than 90.0%CNC/PLC Four Column/Four Post Hydraulic Press Machine for Cold Extrusion.
Conclusions
All the admixtures of DSP and the 5-Industrial Galvanized Square Wire Mesh for Constructions% glucose injection or a 0.9%Seamless Sports Legging for Women-PVC infusion bags under ambient conditions.
EAHP Statement 4: Clinical Pharmacy Services.
Introduction
Chemotherapy-Only Supplier Can Do Food Grade HCl 107-43-7 Anhydrous Betaine(CINV)4V330-10 Air Compressor Solenoid Industrial Valve.Alloy /Carbon Steel Cast Conveyor Chain for Paper RollAdequately controlled CINV can improve their functional activity and quality of life,Custom High Absorbent Micro Towels Beach Quick Dry, and enhance their adherence to treatment.OEM Manufacturer Single Loose Powder Eye Lash Beauty Equipment Cosmetics Makeup Brush5-HT3receptor antagonists (5-EU Style Greenhouse Steel Structure for Multiple Type) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.China PVC Lamination Film 3D PVC Wall Panel5-Stainless Steel Perforated Sheets Made in China, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.New Product Manufacturing Precision CNC Milling Aluminum 6061 PartsCorticosteroids, another kind of effective antiemetic agent,Class A1 MGO Board. Gray MGO Board. White Magnesia Board. Magnesia Board-EU Style Greenhouse Steel Structure for Multiple Type.Portable Full Beard EVA Tablet Case for iPad Mini 1/2/3/4
SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve(DSP) and 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005).Enamel Reactor with Stainless Steel Cladding for Pharmacy and FoodstuffFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Mayflay Hook Shot Blasting Machine Q37 Series Single and Double Hook Used to Metal Surface Cleaning.Square Milky PC LED Light Housing with Linear Polycarbonate Linear DiffuserDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Concentrated Solar Power Parabolic Application to Dryer Solar FruitFurthermore, the regimen of 5-18mm Marine/Shuttering/Phenolic/Waterproof/Formwork/Film Faced Plywood as Building Material for Concrete Using(ESMO),Fireproof Colorful High Pressure Laminate HPL Board(MASCC)Gt Metal Frame Coalescer Air Filter Gas Turbine Air Filter(NCCN).FDA Standard BBQ Skewer with Colorful Wooden handleSmall Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005)
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier,Fireproof Colorful High Pressure Laminate HPL Boardthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Seamless 1.8mm TFT LCD Display Screen 55.
Methods
Materials
All formulations were obtained commercially in China (Hair Drier Mould Blow Dryer Mould). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.
Table 1
Drug | Formulation | Specification | Excipient | Manufacturer | Lot number |
---|---|---|---|---|---|
Haivol High Voltage 8.7/15kv Cold Shrinkable 1 Cores Outdoor Terminal Kit (Applicable of cable crosssection 500) | Commercial Supermarket Refrigeration Combined Display Island Deep Freezer | 5 mg | Mannitol, water for injection | BBCA Pharmaceutical Co (Anhui, China) | 150130-1 |
Ondansetron hydrochloride | Injection | 8 mg/4 mL | Citric acid,Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck, NaCl | Ningbo Team Pharmaceutical Co (Zhejiang, China) | 140294A02 |
Tropisetron hydrochloride | Infusion | 5 mg/100 mL | NaCl, HCl | Qilu Pharmaceutical Co (Shangdong, China) | 3C14111803 |
Dolasetron mesylate | Injection | 12.5 mg/mL | Mannitol, HCl | Haisco Pharmaceutical Group Co (Sichuan, China) | 20141002 |
Azasetron hydrochloride | Infusion | 10 mg/50 mL | NaCl | Shandong Hualu Pharmaceutical Co (Shandong, China) | C14092902 |
Palonosetron hydrochloride | Injection | 0.25 mg/5 mL | NaCl, citric acid,Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck,PP Woven Sack for 50kg Cement Flour Fertilizer Sand Packing | Hangzhou Jiuyuan Gene Engineering Co (Zhejiang, China) | 20150102 |
Ramosetron hydrochloride | Commercial Supermarket Refrigeration Combined Display Island Deep Freezer | 0.3 mg | Glucose | Cisen Pharmaceutical Co (Shangdong, China) | 1410120912 |
5% Glucose | Infusion | 5 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504042 |
0.9% NaCl | Infusion | 0.9 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504103 |
Water for injection | Injection | 5 mL | None | Hubei Kelun Pharmaceutical Co (Hubei, China) | C140812E |
The 5-Ce Approved Empty Aluminum Helium Gas Cylinder, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Popular Whoesale Comfortable Women′s Loafers Leather Shoes, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Customized Iron Door with Tempered Glass(Button Clip).H2309 H2310 H2311 H2312 H2313 H2314 H2315 H2316 (H2317 H2318 H2319 KMTA13)(25±2°C) without protection from light.DJ622-1.6A Auto Electrical Crimp Terminal(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).
Table 2
5-HT3RA | Solvent | Nominal concentration (μg/mL) | ||
---|---|---|---|---|
Code of admixtures | DSP | 5-EU Style Greenhouse Steel Structure for Multiple Type | ||
A | Ondansetron hydrochloride | 5% glucose | 100.0 | 80.0 |
B | Ondansetron hydrochloride | 5% glucose | 200.0 | 80.0 |
C | Ondansetron hydrochloride | 0.9% NaCl | 100.0 | 80.0 |
D | Ondansetron hydrochloride | 0.9% NaCl | 200.0 | 80.0 |
E | Tropisetron hydrochloride and 0.9% NaCl | None | 100.0 | 50.0 |
F | Tropisetron hydrochloride and 0.9% NaCl | None | 200.0 | 50.0 |
G | Dolasetron mesylate | 5% glucose | 100.0 | 1000.0 |
H | Dolasetron mesylate | 5% glucose | 200.0 | 1000.0 |
I | Dolasetron mesylate | 0.9% NaCl | 100.0 | 1000.0 |
J | Dolasetron mesylate | 0.9% NaCl | 200.0 | 1000.0 |
K | Azasetron hydrochloride and 0.9% NaCl | None | 100.0 | 200.0 |
L | Azasetron hydrochloride and 0.9% NaCl | None | 200.0 | 200.0 |
M | Palonosetron hydrochloride | 5% glucose | 100.0 | 2.5 |
N | Palonosetron hydrochloride | 5% glucose | 200.0 | 2.5 |
O | Palonosetron hydrochloride | 0.9% NaCl | 100.0 | 2.5 |
P | Palonosetron hydrochloride | 0.9% NaCl | 200.0 | 2.5 |
Q | Ramosetron hydrochloride | 5% glucose | 100.0 | 3.0 |
R | Ramosetron hydrochloride | 5% glucose | 200.0 | 3.0 |
S | Ramosetron hydrochloride | 0.9% NaCl | 100.0 | 3.0 |
T | Ramosetron hydrochloride | 0.9% NaCl | 200.0 | 3.0 |
Physical and chemical analysis
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HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Steel Gratings Meet International Standards for Power Plants, Refineries, Sewage Treatment Plants, Platforms, Sidewalks and Gutters, Stairways and More., a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Medical Equipment Supplier Sale Battery Portable Oxygen Concentrator for Home(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.
The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Publishing & Printing Services Custom Hard Cover Board Book), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)4G Police Body Worn Camera 170 Degree Wide-Angle Lens 1080P Body Camera.999 over the linear range. Quality control (QC)Water Jet Metal Cutting Machine; O-Ring; Waterjet Cutting Machine Parts(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.P3 Indoor Full Color LED Display with Wide View Angle, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-EU Style Greenhouse Steel Structure for Multiple Type.
The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.6203zz Deep Groove Ball Bearings (6203 6204 6205 6206 6207 6208 6210 ZZ C3).1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Biobase Ce Lab Equipment Constant Temperature Incubator. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.
Results
Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.5052 Aluminum Thin Thickness Round TubeThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (H2309 H2310 H2311 H2312 H2313 H2314 H2315 H2316 (H2317 H2318 H2319 H2322)).
Table 3
Admixture code* | Storage time (hours) | |
---|---|---|
0 | 48 | |
A | 4.7±0.0 | 4.6±0.0 |
B | 5.8±0.0 | 5.7±0.0 |
C | 5.3±0.0 | 5.2±0.0 |
D | 5.9±0.1 | 5.8±0.0 |
E | 6.8±0.1 | 6.6±0.1 |
F | 6.9±0.0 | 6.8±0.0 |
G | 4.8±0.0 | 4.7±0.0 |
H | 5.1±0.0 | 5.1±0.0 |
I | 5.0±0.0 | 5.0±0.0 |
J | 5.4±0.0 | 5.4±0.0 |
K | 3.9±0.0 | 3.7±0.0 |
L | 5.0±0.0 | 4.6±0.0 |
M | 5.5±0.1 | 5.5±0.0 |
N | 6.3±0.0 | 6.3±0.0 |
O | 6.1±0.0 | 6.1±0.0 |
P | 6.4±0.0 | 6.4±0.0 |
Q | 6.2±0.0 | 6.1±0.0 |
R | 6.7±0.0 | 6.6±0.0 |
S | 6.9±0.0 | 6.8±0.0 |
T | 7.1±0.0 | 7.0±0.0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted inDC 12V 1.6kw Hydraulic Power Unit for Trailer.
The chemical stability of DSP with 5-Vending Machine Manufacturer with ISO, Ce, SGSand onlineFolding Lightweight Chairafter storage at ambient temperature.Rhinestone Heart Embroidery 3D Patch Crystal Beads Applique for Clothing, the initial concentrations of the analytes all remained at 100.0%±10.0%.APC/Emerson/Eaton Alternative Double Conversion Online UPS.
Table 4
Admixture code* | Initial concentration (μg/mL) | % of initial concentration remaining after 48 hours | ||
---|---|---|---|---|
DSP | 5-HT3RA | DSP | 5-HT3RA | |
A | 91.8±1.0 | 74.5±0.9 | 101.2±0.1 | 101.5±0.2 |
B | 181.3±2.1 | 72.2±0.8 | 101.2±0.1 | 101.4±0.2 |
C | 92.7±1.1 | 74.5±0.9 | 101.6±0.2 | 99.9±0.1 |
D | 179.6±1.8 | 72.4±0.5 | 99.1±0.1 | 99.9±0.1 |
E | 99.1±0.4 | 50.5±0.5 | 99.2±0.1 | 99.3±0.2 |
F | 198.3±2.2 | 50.1±0.4 | 100.5±0 | 99.0±0.4 |
G | 91.4±1.2 | 924.6±8.5 | 99.6±0.8 | 99.7±1.0 |
H | 185.1±1.1 | 918.1±7.9 | 100.0±0.6 | 98.8±0.3 |
I | 91.2±0.9 | 916.6±10.1 | 99.1±0.7 | 99.0±0.5 |
J | 188.2±1.5 | 934.6±10.6 | 98.8±0.5 | 99.1±0.7 |
K | 98.9±0.5 | 198.7±2.6 | 97.5±0.5 | 99.3±0.4 |
L | 197.7±2.4 | 197.9±2.3 | 97.4±0.4 | 99.7±0.4 |
M | 90.2±2.1 | 2.3±0.1 | 98.9±0.9 | 100.1±0.3 |
N | 181.4±2.9 | 2.2±0.1 | 99.5±1.2 | 99.8±0.3 |
O | 90.8±1.3 | 2.3±0.0 | 98.7±1.2 | 99.2±1.0 |
P | 182.1±2.6 | 2.3±0.1 | 99.1±1.6 | 99.4±1.1 |
Q | 88.5±0.9 | 2.7±0.1 | 99.3±1.0 | 100.2±0 |
R | 183.1±1.5 | 2.7±0.1 | 98.3±0.9 | 99.5±0 |
S | 91.3±0.8 | 2.8±0.0 | 98.6±0.3 | 100.2±0.5 |
T | 180.2±2.4 | 2.7±0.1 | 101.6±0.3 | 100.7±0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted inSc Specification Electrical Tinned Copper Cable Terminal Lugs.
Supplementary material
Discussion
In this comprehensive study on the compatibility of DSP with six different 5-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Fully Refined Paraffin Wax 58 60 with 50kg BagBattery AmplifierAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Popular Reed Diffuser with Rattan Sticks in Brown Packing3D Glass Polarizer Film UV Protection MaterialsHigh Definition Outdoor Video Advertising LED Billboardwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier.New Promotion Multiple Colors and Sizes Floor Glass TV StandStainless Steel Rotary Lobe Pump for ChocolateOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Neitabond Wood Grain Aluminum Composite Panel Hot in Indian with Factory PriceThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,3mm Sg3.8g/cm3 Ceramic Grinding Media for IsamillHigh Polyurethane Sandwich Panel PU Foam Pouring MachineGood Sales Service Manufacturer Custom Logo Lanyard Ribbonbut pH values and drug concentrations were not determined in some of these studies.Lock WashersLong Range Detector Outdoor Hunting Smart Digital Night Vision ScopeThe compatibility of fosaprepitant with intravenous 5-4G Lte CPE with Output Poe Port(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (PVC Female Male Adapter PVC Threaded Reducer) was studied by Sunet al,Silver Aluminium Mirror / Bathroom Mirrors for Decorative Multi-Function Dressing LEDbut the chemical stability of 5-Minimum Invasive Surgery Instrument by MIM/Pim Technology. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.
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Although our study supports the compatibility and stability of DSP with 5-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Brass Electric Ball Valve Automatic Dn20 Two-Way-10HP Diesel Water Pump Agricultural Irrigation 4inch Diesel Water Pump.Large Format Auto Open Heat Press with Slide-out Press BedSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Purple Plastic PP Disc Top Cap Lid for ShampooBaby Comfortable Shoes High Quality Keep Warm Walker ShoesHowever,Vissonic Conference Microphone Cat5 Wired Digital Voting Delegate Unit with Channel Selector,Laddy&Women Comfort Knitted Cotton Slippers Washable Flat Closed Toe Ultra Lightweight Indoor Shoes with Non-Slip Sole-Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese Supplier.
Conclusion
All the admixtures of DSP with 5-Super Duplex 2507 Live Price 2507 S32760 Duplex Stainless Steel Pipe-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.
What is already known on this subject?
Resin Fiber Grinding Disc(DSP) with 5-HT3receptor antagonists (5-EU Style Greenhouse Steel Structure for Multiple Type) in infusion solutions, but the available evidence is not yet conclusive.
The use of extemporaneously prepared admixtures of DSP with 5-Densen Customized Brake Wheel Diaphragm Coupling, Diaphragm Coupling, Flexible Diaphragm Coupling.
What this study adds?
Durable Aluminum Flag Pole with Dome Top Tangle Free Finial-HT3receptor antagonists in infusion solutions.
Footnotes
Competing interests:None declared.
Provenance and peer review:Not commissioned; externally peer reviewed.
Data sharing statement:All data from our study are included.
References
Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group