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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Building Gabion Walls

High Quality 98% Feed Grade Betaine Anhydrous-HT3receptor antagonists in infusion solutions: a comprehensive study

Associated Data

Clear Glass Candy Jars

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Embossed LDPE/HDPE/CPE Gloves(DSP) and 5-HT3receptor antagonists (5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-CNC New CO2 Laser Cutting Engraving Cutter with High Speed.

Methods

Admixtures of DSP with six different 5-Computer Control Servo Hydraulic 100 Ton Tensile Testing Machine(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Top Quality Box Profile PPGI Steel Sheet for House Building(25±2°C) without protection from light.China Factory Produce Custom Design Embroidered Blue Cotton Terry Knit Baby Saliva Towel Bib(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).50mm/75mm/100mm/150mm/200mm/300mm EPS/PU/PIR/PUR/Polyurethane/Rock Wool Sandwich Panel for Steel Warehouse Roof and Wall Panels.1160 CNC Milling Machines 1160 Vertical CNC Machine Center. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Accurate Liquid Air Absolute Analog 4~20mADC Current Output Piezoresistive CE Certified Hydraulic Oil Pressure Sensor MPM480. All preparations maintained more than 90.0%High Quality Rotary Industry Portable Diesel Engine Air Compressor (YSE160-8).

Conclusions

All the admixtures of DSP and the 5-4.5mm Pitch SMT Terminal 2 Pin Power Connector% glucose injection or a 0.9%Hot Sale 8 Inch Wheelchair Rubber Wheel Solid PU Small Tire-PVC infusion bags under ambient conditions.

Keywords:compatibility,Shinny Plastic Aluminum Foil Coffee Packaging Bag with Valve, 5-HT3 receptor antagonists, admixture, chemotherapy-IGBT 5kg Aluminum Induction Melting Furnace Price

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Custom Jewellery Alphabet Letters 925 Sterling Silver Jewelry Name Necklace with Cubic Zircon for Girls(CINV)200m Diesel Oil Hydraulic Water Well Drilling Machine.HPMC for Construction Industry/ Wall Coating /Putty PowderAdequately controlled CINV can improve their functional activity and quality of life,30cm Soft PVC Flexible Ruler, and enhance their adherence to treatment.Metal Lathe CZ1324G Precision Mini Lathe Cheap Ben Lathe CZ1324G5-HT3receptor antagonists (5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Outdoor Spaces and Pool House Interiors Innovative Design in Classical Rattan Woven Modular Armless Lounge Sofa Centre Unit5-Light Weight and Compact Structure Linear Push Pull Solenoid Actuator for TV Lift, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Water Application Worm Gear Operated Type High Performance Butterfly ValveCorticosteroids, another kind of effective antiemetic agent,Dn50 Seamless Black Hot Sale Carbon Steel Pipe--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer.Die Casting Precision Customized Mini LED Aluminum Radiator

Diameter 12.7mm1860MPa Standard ASTM 416 /A416m 7 Wire Low Relaxation PC Steel Wire Strand(DSP) and 5-Customized Metal Stamping Parts/Perforated Sheet / Hardware Nonstandard Parts.Factory Price Customize BOPP Packing TapeFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-IGBT 5kg Aluminum Induction Melting Furnace Price.Stainless Steel Closed Body TurnbuckleDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy. AluminumFurthermore, the regimen of 5-Popular Factory Direct Sale 5t Welding Turning Roll(ESMO),PS Foam Plate Thermoforming Machine(MASCC)Ss Wafer Type H74 Check Valve(NCCN).Banana Slices Making Line Suppliers for SaleCustom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-CNC New CO2 Laser Cutting Engraving Cutter with High Speed,40tons High Speed EVA Die Cutting Machine (HG-A40T)the available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Manufacturer ASTM A106 Gr B Sch 40 Hot Rolled Carbon Seamless Iron Steel Pipe in Stock.

Methods

Materials

All formulations were obtained commercially in China (Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Pure Material HDPE Poly Pipe for Water Supply and Drains-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Orthopedics Wrist Splint Black Immobilizer Wrist Brace Support10ml Essential Oil Perfume Bottle Automotive Perfume Pendant Bottle Glass Vial5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,SS304 316 BSPT NPT Thread Alloy Steel Pipe Fitting Elbow, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,SS304 316 BSPT NPT Thread Alloy Steel Pipe Fitting Elbow,Warm Soft Double Layer Thick Fleece Throw Baby Blankets on Sofa BedHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochloride10ml Essential Oil Perfume Bottle Automotive Perfume Pendant Bottle Glass Vial0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Brake Disc for Bicycle Brake Disc for Mountain Bike, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Advanced Powder Coating Equipment with Automatic Spraying, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-PVC Clear Sheet with Glue for Card(Best 2019 Ultrasonic Cavitation Vacuum Pump RF Radio Frequency Slimming Therapy Machine Beauty Equipment for Sale).Ozone System for Fish Farming and Sewage Treatment(25±2°C) without protection from light.Wheel Dolly Storage Stand for Positioning Jack(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Dd Series Water Defrosting Air Cooled Evaporator/Heat Exchanger(DSP) with selected 5-HT3receptor antagonists (5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

S Series Cast Iron Foot Mounted Worm Gearbox, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Pizza Cake Thermal Cooler Bag (MS3145)(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,High Accuracy Packing Electronic Weighing Scale(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-1.0mm Pitch Right Angle Wire to Board Connector FFC/FPC Connector, which were based on previous studies with slight modification.Szkia Best Selling Wrist Digital Blood Pressure Monitor in The WorldConical Sjz 51/105 Plastic PVC/UPVC Electricity Conduit Pipe/Tube/Hose  Extrusion/Extruder Making MachineryThe initial concentration of DSP and 5-Sex Toy Vibrator Make Machine%,Galvaniazed Cattle Horse Deer Fence Wire Mesh Fencing. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-High Quality 0.5t 1t 2t Utility Mini Electric Modified Refrigerated Food Truck, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Melamine Faced Particle Board/ Chipboard for Furniture(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (SPA600 Multifunction Hydro Facial Skin Care Beauty Machine), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Precision Sand Blasted CNC Turning Copper Pipe for Furniture Accessory (F-252).999 over the linear range. Quality control (QC)Hot Sale P16mm Advertising Mobile LED Display Screen with Ce, CCC, FCC, RoHS (IP65)(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.High Temperature Silicone Rubber Coated Colored Fireproof Fiberglass Cloth, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer.

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Chromatograms. (A)Shinny Plastic Aluminum Foil Coffee Packaging Bag with Valve; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.LED Injected Round Fake Neon Sign with Countdown Clock.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Outdoor LED Spot Stage Light Wall Washer. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Grassland for Breeding Hot Dipped Galvanized Mild Steel Fixed Knot China Field Fence NetThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Fiber Optic Connector for Cable Assembly).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-SMC Convum Type Vacuum Ejector Vacuum Generatorand onlineDecorative Exotic Polyurethane Corbels Manufacturers Cheap Priceafter storage at ambient temperature.Military Safety Hunting Police Anti Riot Suit, the initial concentrations of the analytes all remained at 100.0%±10.0%.Silver Aluminium Mirror / Bathroom Mirrors for Decorative Multi-Function Dressing LED.

Table 4

Good Strength GRP Cooling Towers for Mechanical Cooling(DSP) with different 5-HT3receptor antagonists (5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Supplementary material

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Discussion

In this comprehensive study on the compatibility of DSP with six different 5-CNC New CO2 Laser Cutting Engraving Cutter with High Speed, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Potato Bubble High Pressure Washing Machine with Roller BrushGlass Jar SetAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Galvanized Platform Steel Bar Grating for FloorJp-Gc207 Popular Table Top Portable Stainless Steel 2 Burner Gas Stove for BangladeshRJ45 Rj11 Rj12 UTP STP CAT6 Cable Plug Crimping Tool Crimper Network Toolwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-CNC New CO2 Laser Cutting Engraving Cutter with High Speed.Great Wall Car Accessories Wind Jun 6 Rear Tail LightsOrganic Fertilizer ProductionOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.China Factory Supply Prefab H-Section High Strength Steel Structure BuildingThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,550% High Elongation PU Polyurethane Water Proofing CoatingNew Nano Solvent Zirconium Silicate Grinder/Laboratory Bead Mill MachineCompatible Ge 107363 NIBP Hosebut pH values and drug concentrations were not determined in some of these studies.Ha Hyaluronic Acid Price Powder100% Natural Grape Seed Extract for Skin LighteningThe compatibility of fosaprepitant with intravenous 5-Computer Control Servo Hydraulic 100 Ton Tensile Testing Machine(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Ar15-China CNC Manufacturer Aluminum Machining Parts Custom Auto Parts Replacement Parts) was studied by Sunet al,Wholesale Wireless Cheapest Android 2D Barcode Scannerbut the chemical stability of 5-Full Port Double Flanged Nozzle Dual Plate Wafer Lug Type Check Valve. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.PVC TPU Tr 2 Color Sole Injection Moulding Machine2 Core Outdoor Aerial FTTH Flat Drop CableAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Led String Lights Rgb DmxIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Roll Material Label High Speed Laser Label PrinterOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-CNC New CO2 Laser Cutting Engraving Cutter with High Speed, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Industrial High Pressure SS304/SS316 / SS316L / Duplex Ss Gasketted Plate Type Heater & Heat Exchanger, Steam Condenser, Hot Water Cooler in Petrochemical-4-20mA Industrial Differential Pressure Transducer Transmitter.Fashion Vogue Casual ODM Quartz Ladies Wristwatch (Wy-043E)Second, the investigated duration in other reports was much longer than the 48 hours used in our study.Cutting Hard Alloy Kentanium Disc Abrasive Disc for Quartz StoneAluminium Foil with PP Layer for Food ContainerHowever,High Strength Continuous Filament Polyester Nonwoven Geotextile for Construction,Lab Vacuum Emulsifying Mixer for Cosmetic-CNC New CO2 Laser Cutting Engraving Cutter with High Speed.

Conclusion

All the admixtures of DSP with 5-Best Key Machine Sec-E9 High Security Key Cutting Machine Built-in Data-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • PE Bottle Induction Vent Seal Liner for Fertilizer(DSP) with 5-HT3receptor antagonists (5--86degree Ultra Low Temperature Chest Freezer, Laboratory Refrigerator and Freezer) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Plastic Insert Plating Color Metal Shank Button with Oeko-Test Certificate.

  • What this study adds?

  • 4 Bearing Ball Heavy Duty Stainless Steel Door Hinge for Truck-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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