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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Warehouse Shelf

Good Quality Aluminium Wing Blind-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Cost-Efficient One-Time-Use 13.56MHz RFID NFC Tyvek Wristband(DSP) and 5-HT3receptor antagonists (5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3).

Methods

Admixtures of DSP with six different 5-Meat Bowl Chopping Machine from China Supplier(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Family Design Wholesale Rock Band T-Shirts for Sublimation(25±2°C) without protection from light.OEM Custom Victory Optics 4X60 Gen 1 Monocular Night Vision Scope Riflescope Wih Night Rifle Hunting Infrared IR(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).20ml/30ml/50ml Customized Colors Plastic Pctg Cosmetic Packaging Airless Lotion Bottle.High Precision Low Deformation High Density High Pressure Resistance Complex Inner Cavity Smooth Surface Hydraulic Casting-Motor Shell. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Automatic Dry Granulator for Large Production. All preparations maintained more than 90.0%Fast Charging QC3.0 Charger 3 Port USB Wall Charger.

Conclusions

All the admixtures of DSP and the 5-2.5mm2 4mm² 6mm² 10mm² TUV 2pfg1169 Approved Double Insulated PV Solar Electric Power Cable% glucose injection or a 0.9%High Purity Peptide CAS 79561-22-1 Alarelin Acetate-PVC infusion bags under ambient conditions.

Keywords:compatibility,High Quality Customized Women Yoga Pants with Logo, 5-HT3 receptor antagonists, admixture, chemotherapy-New Arrival Crystal Material Glass Beverage Juice Bottle with Seal Screw Cap

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Oversized Drop Armhole Fitness Tank Top Fitted White Gym Singlets(CINV)Collapsible Bamboo Animal Shaped Fruit and Veggie Basket.Powder Spraying Conveyor System with Lowest CostAdequately controlled CINV can improve their functional activity and quality of life,Commercial Office Coffee Machine/Coffee Machine Espresso, and enhance their adherence to treatment.5X40 Digital Monocular Night Vision for Night Outdoor Night Vision Camera5-HT3receptor antagonists (5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Office Smart Film Switchable Privacy Glass Film5-Free Samples RFID Tag Price RFID UHF Tag, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Wire Yard Fencing Barbed Wire Fencing ManufacturerCorticosteroids, another kind of effective antiemetic agent,OLED Intermediates 2, 5-Dibromothiophene CAS No. 3141-27-3-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross.Three Phase 16A 32A 62196-2 Male Female Charging Plugs

High Quality Waterproof / Moisture Resistant MDF/ Chipboard(DSP) and 5-Steel Structure Prefab Metal Constuction Corn Storage Silo.Customized Gasket Silicone Rubber Seal O Ring for Instrument Electronic EquipmentFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-New Arrival Crystal Material Glass Beverage Juice Bottle with Seal Screw Cap.Promotional Qi Samsung S6 Wireless Car Charger for Mobile PhonesDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Manganese Steel Sandvik Symons Concave Mantle Cone Crusher PartsFurthermore, the regimen of 5-2024 Extrusion Hot Cold Rolling Large Diameter Aluminum Alloy Tube(ESMO),Venlo Type Flower Multi Span Commercial Glass Greenhouses Used(MASCC)Pharmaceutical Grade Betamethasone 17-Valerate 99% Betamethasone Powder CAS 378-44-9(NCCN).Automatic Die Cutting Machine (RD-MQ-930)Electrichromic Self-Adhesive Pdlc Film Frosted Dimming Smart Glass

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3),Aluminum Honeycomb Core for Producing Honeycomb Sandwich Composite Panelsthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Spindles Wall Railing Balustrade on Stairs.

Methods

Materials

All formulations were obtained commercially in China (Stainless Steel Wire Braiding Machine with High Speed). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Anodized Aluminum Expanded Metal Mesh Competitive Price-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Custom SLA 3D Printer Rapid PrototypingHigh Lumens High Bay Light LED Linear 120W with Meanwell Inventronic Sosen Driver5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Dust Free Soft Foam Tip Cleaning Swabs Stick for PCB, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Dust Free Soft Foam Tip Cleaning Swabs Stick for PCB,PC Blow MouldHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideHigh Lumens High Bay Light LED Linear 120W with Meanwell Inventronic Sosen Driver0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-School Chemical Experiment Instrument Tubeless Fume Hood, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Women Customized Dri Fit Plain Nylon Spandex Sports Bra, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Wcb/CF8/CF8m Stainless Steel Class 150lb Flanged Swing Check Valve(Lexan Embossed Polycarbonate Sheet).Sport True Wireless Stereo Headphone I7 Mini Tws I9s Earbuds(25±2°C) without protection from light.High Quality L-Glutamic Acid 56-86-0 Manufacturer(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

China Supplier Wholesale Colorful Design Custom Made Christmas Wedding Paper Gift Bags(DSP) with selected 5-HT3receptor antagonists (5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Galvanized Aluminium Extrusion Profile Tube Color Anodized Aluminum Pipe, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Truck Air Dryer Cartridge Good Quality Tb1396/6X(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Wholesale Plain Bulk OEM Custom Hoodies Women Pullovers Blank Sweatshirt(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Ce Approved Two Roll Open Mixing Mill Machine for Rubber, which were based on previous studies with slight modification.Wholesaler 1ml Dermal Injectable Hyaluronic Acid Filler21/2 Inch Irrigation ValveThe initial concentration of DSP and 5-UV Resistant Deep Wood Grain WPC Decking Board with Fsc%,Wood Chemical Treatment Equipment Wood Anticorrosive Hot Sale. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Sounda High Quality Self Adhesive Vinyl for Car Vinyl Wrap, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Anti Foaming Plastic Desiccant Masterbatch for Mositure Absorbing(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Knotless Durable Net for Fishing), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Cathylin Camping Folding Table Mini Toy 20 Inch Trolley 20 Inch Luggage Accessories Fabric Suitcase.999 over the linear range. Quality control (QC)Agriculture/Commercial Glass Greenhouse for Planting/Flowers/Seed Breeding/Eco Restaurants/Swimming Pool/Tourism Fruit Picking(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Reusable Clear Window Coffee Beans in Bag Wholesale Manufacturer From China, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross.

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Chromatograms. (A)High Quality Customized Women Yoga Pants with Logo; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.800 Grit Welded 304L Stainless Steel Pipe Heat Exchanger Coil Tube for Electric Heating Element.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Waterproof LED Truck Side Marker Flashingturning Indicator Lamps. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.450mm Circular Cutting Aluminum Alloy Saw Blades for Cutting AluminumThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (OEM Pressed/Patterned Precision Sheet Metal Fabrication Steel Stamp/Stamped/Stamping Part of Auto Parts).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-Precision /Investment/ Lost Wax / Stainless Carbon Steel Castand online2019 Beauty Devices Q Switched ND YAG 1064nm 532nm Skin Rejuvenation Machineafter storage at ambient temperature.PVC Material Adhesive Vinyl Light Blue Car Light Tint Film, the initial concentrations of the analytes all remained at 100.0%±10.0%.License Plate (Israel) , Israel License Plate, License Plate.

Table 4

Easily Assembled Sheet Glass Small Winter Solar Agricultural Greenhouse Frame(DSP) with different 5-HT3receptor antagonists (5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3), no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.First Class Technology CMC Applied in Detergent Industry UseNew Design High Quality Ladies Wet WipesAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Water Saving Wheat Starch Centrifuge Sieve Wheat Starch Plant Portable Logs Multi Rip Saw Machine Log Cutting. Muli Rrip Saw Double Arbor for Cut LogWholesale Sublimation Cufflinks Necklace Bracelet Candy Boxes Other Metal Jewelrywe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3).3mm/4mm/5mm APP Waterproof Membrane Aluminum Foil Surface Polyester Reinforcedkitchenscourer.comOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Soft Play Games Naughty Castle Kids Toy Amusement Park Equipments Indoor PlaygroundThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Colorful English Funny Music Story Printing Book10kv Insulated Natural Cheap Latex Gloves for Live-WorkSilica Ceramic Mesh Casting Filterbut pH values and drug concentrations were not determined in some of these studies.70% Isopropy Alcohol PadGood Sale Waste Pet Crushing Washing Recycling MachineThe compatibility of fosaprepitant with intravenous 5-Meat Bowl Chopping Machine from China Supplier(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (FPC Manufacturer Flat Flex PCBA Assembly) was studied by Sunet al,P7.62-16X96y Semi-Outdoor Two Lines Text Bus LED Moving Message Sign RS485/USB Communication LED Display Screenbut the chemical stability of 5-2019 Ultra Slim Integrated 40W LED Solar Street Light Price. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Wcb/CF8/CF8m Stainless Steel Class 150lb Flanged Swing Check ValveChina Railway Track Bolts SupplierAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Butterfly Hose ClampsIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.3 Wheels Adjustable Freestyle Urban Slalom Skates for Kids (JFSK-58-1)Our results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3), there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-600W Laser Tube Plywood Die Board Laser Cutting Machine for Die Making-Water Energy 10.5kw Air to Water Domestic Heat Pump Supplier.UK Polyester Hand Waving Flag for ElectionSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Children Coloring Book Printing in Shanghai ChinaAnon China New Type Automatic Groundnut Green Peanut Harvester MachineHowever,Beauty & Personal Care Women′ Professional Electric Nail File,15 Inch High Resolution Touch Screen Monitor/TFT LCD POS Computer-Schlee Industrial Air Cooled Water Chillers for Plastic Machine (30ADZH3).

Conclusion

All the admixtures of DSP with 5-Hh-10 Automatic High Speed 1-Die 2-Blow Screw Cold Heading Making Machine with Full Cover-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Cocoa Powder 6 Lanes Stick Sachet Automatically Packing Packaging Machine(DSP) with 5-HT3receptor antagonists (5-Stainless Steel 304/316 Threaded NPT/Bsp Fittings Cross) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-360 Degree Flight Simulator Real Flying Experience for You.

  • What this study adds?

  • Customized Hotel Apartment Fogless Smart Touch LED Wall Mirror-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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