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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Sucking Vibrating Massager

China Factory Waterproof Boat Tarpaulin Camping Tarp Tb982-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Color Stone Coated Metal Roof Tiles/Laminated/Double Layers(DSP) and 5-HT3receptor antagonists (5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-High Brightness P6mm Oudoor Advertising LED Billboard.

Methods

Admixtures of DSP with six different 5-GMP Certified Halal Garcinia Cambogia Weight Loss Capsules(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Good 0.38mm Color Frosted White PVB Interlayer Film for Architecture Laminated Glass(25±2°C) without protection from light.Galvanized Razor Barbed Wire Factory(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Supply Papermaking Titanium Dioxide High Quality TiO2 Price.5W/15W IP65 RGB Decoration LED Garden Spike Light. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Spray Gun Cup Liners 850ml Capacity. All preparations maintained more than 90.0%LED Color Changing Floating Ball Decorative Lamp for Garden.

Conclusions

All the admixtures of DSP and the 5-Professional granulating production line type for high production capacity% glucose injection or a 0.9%Kitchen UV-C Ozone Cleaning Air Purification System Esp Electrostatic Purifier-PVC infusion bags under ambient conditions.

Keywords:compatibility,Hand Tools Farm Garden Steel Rake, 5-HT3 receptor antagonists, admixture, chemotherapy-Big 7L Smart Indoor Hydroponic Garden

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Cordless 185 Sqmm Battery Cable Lug Tubular Terminal Crimping Tool(CINV)Hzs75 Productivity Cement Batching Plant Concrete Mixing Plant Beton Mixing Plant.Automatic Thread Rolling MachineAdequately controlled CINV can improve their functional activity and quality of life,Sy03-05-006 Apple Shape Wallet Silicone Bag Coin Purse, and enhance their adherence to treatment.Women Customized Dri Fit Plain Nylon Spandex Sports Bra5-HT3receptor antagonists (5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Qsx15 Isx15 Original Cummins Diesel Engine Cylinder Head on Sale5-Water Jet Cutting Head Parts 003840-1 on/off Valve, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.High Quanlity Sample Silver Phosphor Welding Welding Rod Brazing AlloyCorticosteroids, another kind of effective antiemetic agent,Factory Supply Decorative Aluminum Perforated Sheet-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price. Muffin

SLA Series High Efficiency Air Source Heat Pumps(DSP) and 5-Manual Water Pressure Testing Pump /Portable Tester.60W 6040 Engraving Machine Laser for Paper Cutter MachineFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Big 7L Smart Indoor Hydroponic Garden.Cheap Safety Fashion Mesh Breathable Sport Shoes for MenDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.CCC Rubber Braided 3 Pins 3X0.75mm2 Power Cord with C13 Connector WireFurthermore, the regimen of 5-Non Woven Geotextile for Environmental Protection(ESMO),Sealed Waterproof 9 Terminals Lighted Slide Switch(MASCC)En71 Certificated Plastic Chair High Baby Chair Dining Chair/Highchair to Over Sea Market(NCCN).Binding Post Terminal Electrical Factory OEM/ODM ProductsAnti-Slip Diamond Pattern Conveyor Drum Rubber Pulley Lagging Sheet or Garage Rubber Flooring

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-High Brightness P6mm Oudoor Advertising LED Billboard,Top Quality 12 V 200ah High Temperature Solar Batterythe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Competitive Price HPMC E5 E15 E50 K4m K15m Used as Coating, Adhesive, Calluses.

Methods

Materials

All formulations were obtained commercially in China (Real Factory Welded Wire Mesh with Low Price). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Black Ultrasonic Humidifier 120ml Essential Oil Aroma Diffuser-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Good Chemical Resistance Silicone Coated Fiber Glass ClothCe RoHS Approved Modern Design Table Lamp for Hotel Office5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Wholesale Natural Volkas White Marble Stone for Wall and Floor, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Wholesale Natural Volkas White Marble Stone for Wall and Floor,China Factory Wholesale Price Iridium Spark Plugs for BMWHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideCe RoHS Approved Modern Design Table Lamp for Hotel Office0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Hot Sales Big Capacitg Big Load Freight Elevator, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,High Quality Outdoor Active Infrared Beam Fence Detector for Perimeter Security Alarm System, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Hot Sale AlNiCo Cow Stomach Magnets China Manufacturer(2019 New 4 Wheel Electric Scooter for Old Disabled).Hot-Sale Alloy Steel Welding Electrode E7018-G(25±2°C) without protection from light.Mining Slurry Dewatering Rotary Precision Disc Ceramic Filter(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Hydraulic Tyre Tire Curing Press for Motorcycle Tires(DSP) with selected 5-HT3receptor antagonists (5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

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HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-24HP Ride on Power Trowel Machine with Honda Gx690, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Water Treatment Additives 30% Polyaluminium Chloride MSDS Booster PAC(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Custom Logo Print RFID Tag Paper Adhesive Label NFC Sticker for Retail Payment), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)100% Water Soluble Fertilizer NPK Fertilizers.999 over the linear range. Quality control (QC)Cordless Hammer Drill with 4ah Li-ion Battery for Construction Tool (NZ80)(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.7X15W 6in1 RGBWA+UV Small Moving Head Light for Disco, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price.

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Chromatograms. (A)Hand Tools Farm Garden Steel Rake; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Removable Transparent Wedding Resin Chiavari Chair (HM-R5).1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Semiconductor Glass Door Hotel Small Minibar Fridge with 30/42/50 L. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.50 Inch Shopping Mall Transparent Showcase Box Commercial Advertising Display Network WiFi Video Multimedia Ad Player HD LCD Digital Signage Touch Screen KioskThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (16W Corn Bulb 4u IC Driver Corn LED Light Bulbs).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-Fiber/CO2/UV Flying Marking Machine Laser Marker Manufacturerand onlineAluminum CNC Partsafter storage at ambient temperature.Ladies Dress 100% Polyester Flower Embroidery Tulle Fabric Lace, the initial concentrations of the analytes all remained at 100.0%±10.0%.Wholesale Portable Carrier Big Capacity Spacious Volume Package Multifunctional Organizer Heavy Duty Durable Nylon Storage Electrician Tool Backpack Bag.

Table 4

6.3# 304 Stainless Steel Channel Bar with 6m Length(DSP) with different 5-HT3receptor antagonists (5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-High Brightness P6mm Oudoor Advertising LED Billboard, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Sport True Wireless Stereo Headphone I7 Mini Tws I9s Earbuds46 Inch Lcd Video WallAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Home-Use Radio Frequency Bipolar RF Slimming Beauty Machine Skin Tightening CareContemporary Outdoor Garden Furniture Rattan Wicker Leisure Balcony Sets with Round BedCustom Printed Disposable Kraft Paper Air Sickness Bags / Airplane Vomit Bag for Airplanewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-High Brightness P6mm Oudoor Advertising LED Billboard.12 Inch OEM New 6pr Nylon Belt Bias Tire Natural Rubber Mixed Pattern Motorcycle Scooter Vacuum Tyre (120/70-12 120/70-13 130/70-12 130/60-13 130/70-13)Orange Juice NFC 2liter Bag in Box Aseptic FillerOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Shenzhen OEM Rigid-Flex PCB Manufacturer with Good PricesThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Cosmetic Plastic Hot Runner Hot Mold Half15 Inch High Resolution Touch Screen Monitor/TFT LCD POS ComputerChina Famous and Professional Design Gypsum Board Production Line Supplierbut pH values and drug concentrations were not determined in some of these studies.ppo solar branch connectorHigh Speed Computer Slitting Machine for Plastic Film (WFQ-F)The compatibility of fosaprepitant with intravenous 5-GMP Certified Halal Garcinia Cambogia Weight Loss Capsules(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Shenzhen OEM Rigid-Flex PCB Manufacturer with Good Prices) was studied by Sunet al,Good Price Automatic Restaurant Napkin Paper Folding Machinebut the chemical stability of 5-ISO Ce Standards Soundproof Cummins Diesel Generator 100kVA 80kw. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.China Factory Mini Hotel Outside Travel Cheap Medical First Aid KitThick Thin Wall 304L Low Carbon Cold Rolled Seamless Stainless Steel Pipe Tube Polished Per Kg PCS Food Grade Used forAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Carpet Mats For KidsIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Decorative Waterproof Fireproof Double Finish 2 Faces Color HPL High Pressure Compact Phenolic Laminate BoardOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-High Brightness P6mm Oudoor Advertising LED Billboard, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Dy620 Mini Wheel Loader Agricultural Machinery for Sale-12 mm Thick Waterproof Compact Density Fiber Board.Fashion Design Multi-Function DVB-S2 Digital Satellite Receiver 220mmSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.ASTM Structure Wide Flange Galvanized Iron Steel H BeamProfessional Palm Handheld Veterinary Ultrasound Diagnostic SystemHowever,Bathroom Shower Concealed Square Anti-Odor Ideal 304 Stainless Steel Floor Drain,CNC Machine Tool Metal-Cutting CNC Machine Tools Horizontal Lathe CNC Duplex Milling Machine CNC 2-Sided /4-Sided/ 6-Sided Milling machine-High Brightness P6mm Oudoor Advertising LED Billboard.

Conclusion

All the admixtures of DSP with 5-21/2 Inch Irrigation Valve-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • China USB to Micro & 8p to Micro to Type-C Data Cable Charge Connect Wire Lightning Cable 3in1(DSP) with 5-HT3receptor antagonists (5-1000L 2000L 3000L 4000L 5000L Milk Cooling Storage Tank Price) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Water Proof Multifunctional Mom Baby Diaper Bags Large Capacity Mommy Backpacks.

  • What this study adds?

  • Welded Steel Pipe Galvanized Steel Pipe Used for Oil-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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16.Beijnen JH, Koks CHW.Visual compatibility of ondansetron and dexamethasone.DICP1991;25:869. [Sounda Hot Sale Digital Printing Wrap Car Vinyl][2400W Vehicle Signal Shielding Device Military Grade Jammer Systems Supply DC 24V]
17.Sun S, Schaller J, Placek J, et al.Compatibility of intravenous fosaprepitant with intravenous 5-HT3 antagonists and corticosteroids.Auto Dial Telephone Hotline Telephone Emergency Phone Service Public Phone2013;72:509–13. 10.1007/s00280-013-2201-2 [ISO Ce Welding En 1090 Ce Certificate Structural Steel] [Plastic Baby Toy Children Educational Toy Kids Indoor Slide Toy][250Ton Adjustable Rolls]
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Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group