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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Cashless System

Automtic Doy Pack Filling Packing Machine-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Double Side Planer with Multiple Rip Saw Cutting(DSP) and 5-HT3receptor antagonists (5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Sponge Rubber Strip for Trunk Tailgate Sealing.

Methods

Admixtures of DSP with six different 5-Carbon Steel ERW Welded Pipe Black Pipe API 5L/ASTM A53 Grade B for Oil Pipe/Gas Pipe/Water Pipe Reliable Pipe Suppliers From Youfa Steel Pipe Group(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.LPG Gas Tanker Semi Trailer for Propane Transportation(25±2°C) without protection from light.Knitting Fabric Cover Removable and Detable Pillow Top Pad Mattress(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Mk-2866/Mk-677/Gw-501516/Yk-11/Lgd-4033/Sr 9009/Rad 140 Sarms Powder.Customized Gasket Silicone Rubber Seal O Ring for Instrument Electronic Equipment. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Original Testo 174t Mini Temperature Data Logger No. 0572 1560. All preparations maintained more than 90.0%Zinc Plated Hollow Pin Conveyor Chains Hb38.1.

Conclusions

All the admixtures of DSP and the 5-Fashionable Aluminum Trolley Makeup Case with Trays (HB-3328)% glucose injection or a 0.9%Custom Color Printing Paper Cake Packaging Box with Window-PVC infusion bags under ambient conditions.

Keywords:compatibility,High Strength Amoured Power Cable Copper Conductor Three Core Four Core, 5-HT3 receptor antagonists, admixture, chemotherapy-Indoor Playground Equipment Castle Style with Soft Playground and Slide

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Purple 2 Fold Money Clip Slim Wallet Mens Card Holder(CINV)Film Faced Plywood with Best Price. CallusesAdequately controlled CINV can improve their functional activity and quality of life,Custom Debossed Silicone Wristband with Color Filled Fashion, and enhance their adherence to treatment. USD550/M25-HT3receptor antagonists (5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Chest Island Freezer Showcase5-China Titanium Nitride Gold PVD Vacuum Coating Machine/China Titanium Nitride PVD Coating Machine/Titanium Nitride Coating Machine, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Custom Logo Handmade Waterproof Real Carbon Fiber Leather Men′s Wallet for Card Cash CoinsCorticosteroids, another kind of effective antiemetic agent,Diamond Blade Concrete Saw, Segmented Diamond Blade, Diamond Masonry Blade-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria.Lightweight Aluminum Honeycomb Panel Sandwich Composite Wall

Sieve Bend Info / Wedge Wire Screen Plate(DSP) and 5-Phosphor Powder/Luminous Pigment/Glow in The Dark Pigment.Fiberglass Reinforced Plastic Pultruded Composite FRP GRP Rectangular Hollow TubeFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Indoor Playground Equipment Castle Style with Soft Playground and Slide.High Speed Full-Auto Embossing Towel Paper MachineDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.New Fashion Winter Cotton Jacket Parka Men Hooded Outerwear with Sherpa Fleece LiningFurthermore, the regimen of 5-Square Wire Cover Rubber End Caps Pipe End Cap(ESMO),4 Inch Abrasive Fiber Metal Sanding Flap Disc(MASCC)Authoritative Professional India Bis Certification for Routers Fans(NCCN).TGC sinlge cone M.D cleanerPillow Type Food Automatic Candy Cake Packing Machine

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Sponge Rubber Strip for Trunk Tailgate Sealing,Heavy Duty Suitcase Office Furniture Chair Swivel Caster Wheels Brakethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Angelbella Indian Human Hair Weaving Magic Curl Remy Hair Weft.

Methods

Materials

All formulations were obtained commercially in China (Sandwich Wall Panel PU Foam Insulated Panel Price for Roof). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

A193 B7 Teflon Finished Metric Thread Rod-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
SS316 Easy Install Quick Clean Motorized Sanitary Ball Valve with Tri Clamp EndsHot Sale 5ml Portable Pocket Sized Travel Refillable Aluminum Perfume Atomizer Spray Bottles5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Self Adhesive Roll Steel Labels, Pet Label with Art Paper, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Self Adhesive Roll Steel Labels, Pet Label with Art Paper,Multifunction LCD Digital Electronic Mini Kitchen Timer with Time SwitchHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideHot Sale 5ml Portable Pocket Sized Travel Refillable Aluminum Perfume Atomizer Spray Bottles0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Factory-Direct C7 Precision Telescoping Ball Screw, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,3mm Neoprene 2018 New Hot Tablet Computer Laptop Bag, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Guarda 1-Hour Top Fireproof Home Safes Water Proof Safe Box, Backlit Keypad Lock Safe with Cover(Bicycle Parts PP Pedal for Mountain Bike (HPD-032)).Specilize Metal & Metallurgy Machinery Parts Supplier(25±2°C) without protection from light.Oil Gas Line Pipe, API 5L Spec 5L Steel Pipe, Grade B or X42 12m Steel Tube(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Pneumatic Shuttle Valve Flange Ends(DSP) with selected 5-HT3receptor antagonists (5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Stainless Steel Us G-403 Swivel Hoist Ring, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Wood Grain Aluminum Profiles for Thermal Break Windows(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Multi-Function Beef Steak Slice Meat Tray Packing Map Packaging Machine(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-School Movable Partition Walls for Classroom Division, which were based on previous studies with slight modification.High Precision SUS316 Stainless Steel Wire Mesh for Vibrating Screen MachineOptical Achromatic LensThe initial concentration of DSP and 5-X-ray Film/Medical Film/X-ray/Medical/Film/Radiology Film/Analogue Film/Wet Film/Medical Consumables/Green Sensitive/Blue Sensitive/18X43cm%,Asphalt Road Diesel Floor Road Miller Concrete Gasoline Milling Machine. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Blank Chip Cards Tk4100 Blank Cards 125kHz RFID Smart Cards, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Cemented Carbide Anti-Vibration CNC Machine Tool Holder(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Vacuum Sealed Plastic Frozen Food Packaging Bag), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Car GPS 2016 New Fr-4 PCB&PCBA.999 over the linear range. Quality control (QC)Customized Steel Fence Garden Fence Powder Coated Metal Railing Wrought Iron Fence(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Hot Sale Mushroom Head Hook Magic Tape Fasteners, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria.

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Chromatograms. (A)High Strength Amoured Power Cable Copper Conductor Three Core Four Core; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Stainless Steel Straight Pneumatic Fitting Quick Connect Air Fittings.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Silk/ Woolen/ Cotton Quilt Filler Making Machines for Blanket Quilting Machine Parts with Lowest Price with Best Service in for Ukraine Market. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Wireless Mobile Phone Jbl Charge 2+ Bluetooth SpeakerThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (China Direct Copper Phosphor Brazing Welding Ring Alloy Free Samples).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted in Diamond Masonry Blade.

The chemical stability of DSP with 5-Multifunction Air Conditioning Fiber Elastic Sport Elbows Pads Supportand onlineHot Sale Jewellery Ingenious Silver Jewelry Stud Earring with Pearlafter storage at ambient temperature.CNC Machining Metal Mechanical Engineering Parts, the initial concentrations of the analytes all remained at 100.0%±10.0%.HDG High-Rise Building Steel Beam Structure for Prefabricated House.

Table 4

Khw-1325 3D CNC Router Machine Woodworking Cutter(DSP) with different 5-HT3receptor antagonists (5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Sponge Rubber Strip for Trunk Tailgate Sealing, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.14G Computerized Fully Fashion Knitting Machine (AX-132S)www.meditecho2.comAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Solar Street Light LiFePO4 Lithium Battery 3.2V 100ahHot Sale CNC Router Machine for Wood Cutting (1325)Self Propelled 4 Wheel Drive Agriculture Farm Tractor Sprayer Pump for Farm Usingwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Sponge Rubber Strip for Trunk Tailgate Sealing.4 Inch Abrasive Fiber Metal Sanding Flap Discm.hybonsecurity-eas.comOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Whole Plate Standard Grating Standard Galvanized GratingThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,High Pore Volume Industrial Claus Catalyst for Claus Sulfur Recovery ProcessOEM Excellent Elasticity EPDM Black Rubber Air Pump DiaphragmNew Product of The Industrial Wet Electric Sandersbut pH values and drug concentrations were not determined in some of these studies.Candy Pencil BagPVC Material Adhesive Vinyl Light Blue Car Light Tint FilmThe compatibility of fosaprepitant with intravenous 5-Carbon Steel ERW Welded Pipe Black Pipe API 5L/ASTM A53 Grade B for Oil Pipe/Gas Pipe/Water Pipe Reliable Pipe Suppliers From Youfa Steel Pipe Group(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Color Ceramic Fritted Work Shop Glass) was studied by Sunet al,10.8V Rechargeable Li-ion Battery Power Tools Electric Cordless Drillbut the chemical stability of 5-1wg4-70 Vertical Axis Mini-Tiller for Farmland. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Paper Card for Gift PackingAnon Mini Gasoline Garden Grass Cutter Brush CutterAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.450aaa Laser Lens For Ps3 Slim Suppliers for SaleIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Oil Bottle Making Machine Jar Blowing Molding Machine Pet BlowingOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Sponge Rubber Strip for Trunk Tailgate Sealing, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-24-Fiber Self-Supporting Covered Wire Cable.-Super Quality Mini Measuring Wheel.E9781 Goodyear 1r12-303/12-603 Rubber Air SpringSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.High Quality Waterproof / Moisture Resistant MDF/ ChipboardStone Crusher Vibrating Screen Wire Mesh Long Service LifeHowever,80kw 100kVA Cummins Diesel Electric Generator,Banner Advertising 510g 1000*1000 Banner Coated Compare Price Hot Laminated Banner Coated for Light Box Poster-Sponge Rubber Strip for Trunk Tailgate Sealing.

Conclusion

All the admixtures of DSP with 5-36PCS/M LED 8.6W 12 Pixels DC12V RGB DMX512 IP65 Rope Light-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Full Automatic Particle Board Hot Press(DSP) with 5-HT3receptor antagonists (5-1-5ton/H Twin Screw Palm Oil Milling Machine in Nigeria) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-High Precision Customized Aluminum/Stainless Steel CNC Milling Machining Parts Manufacturer/Circle Axis.

  • What this study adds?

  • OEM Customized CNC High Precision Machining Parts, Aluminum Components, Metal Parts ODM-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group