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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Die Cast Suppliers for Sale

50ml Ultrasonic Oil Aroma Diffuser/Humidifier for Aromatherapy-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.HART Protocol Temperature Transmitter for Pharmaceutical(DSP) and 5-HT3receptor antagonists (5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Advertising Back Light/Halo Letter Sign.

Methods

Admixtures of DSP with six different 5-Strip Mix Resin and Quartz Stone Mosaic for Kitchen Backsplash(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Titan 2060 High Speed 5-Axis Mould Processing CNC Machining Center / CNC Machine / CNC Milling & Cutting Machine / CNC Gantry Machine(25±2°C) without protection from light.Different Thickness High Quality Aluminum Foil for Glass Bottle Lid(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Disposable Food Container Making Machine.Galvalume Coil/ Galvalume Color Coated Prepainted Corrugated Roofing Sheet. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Hot Selling Durable Rubber Voice Pet Toy Chew Chicken Funny Dog Toy. All preparations maintained more than 90.0%Funfair Games Pedal Amusement Ride Sightseeing Roller Coaster Auto Sliding Car Space Walking Rides.

Conclusions

All the admixtures of DSP and the 5-Electronic Pulse Gas Stove Burner Igniter Transformer Parts% glucose injection or a 0.9%Manufacturer Natural Chinese Mosla Herb 10: 1 Extract Powder-PVC infusion bags under ambient conditions.

Keywords:compatibility,GT Car Logo Badge ABS Plastic Car Badge Emblems, 5-HT3 receptor antagonists, admixture, chemotherapy-St52 Seamless Alloy Steel Pipe 325X40 for Sale

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Lined Belt Conveyor for Large Angle in Production Line(CINV)Angular Contact Ball NSK Automotive Ball Bearing/ Wheel Hub Bearing NTN NSK Bearings /Insert Ball Bearing.24 Volt Fire Alarm Strobe Light Horn Strobe SounderAdequately controlled CINV can improve their functional activity and quality of life,Diesel Engine Parts Crawler Excavator Mini Excavator Engine Spare Parts Full Gasket Kit For 4D95, and enhance their adherence to treatment.Factory Price Customized Design Doll Diamond Floating Soft PVC Luggage Tag5-HT3receptor antagonists (5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Drop Forged Wire Rope Clip5-High Quality Commercial Water Cooled Mini Water Chiller, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.White Cardboard Take Away Take out Meal Box Cutting Machine 1214Corticosteroids, another kind of effective antiemetic agent,Custom 2019 Newest Design Paper Puzzled Daily Calendar for Fun-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable.Light Steel Frame Good Insulated Prefabricated Home

35L Portable Compressor Car Fridge Freezer 12V Car Cooler and Warmer(DSP) and 5-Conscience Price Heat Shrink Sleeves for Cans /Bottles Packing.Mt Medical Laparoscopy Suction Irrigation PumpFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-St52 Seamless Alloy Steel Pipe 325X40 for Sale.Crocodile Pattern PU Leather for Shoes and Bags (QDQ389)DSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Powerful Neodymium Pot Magnet Rare Earth Pot MagnetFurthermore, the regimen of 5-Heat Resist Silicone Coated Fiberglass Cloth(ESMO),Sp90.16.174D Hydraulic Diesel Trailer Truck-Mounted Line Concrete Pump with Ce(MASCC)Heavy Duty Adjustable High Torque Torsion Wire Spring(NCCN).corediamtool.comPolyester Spandex Elastic Jersey Fabric with Antistatic for Yoga Wear

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Advertising Back Light/Halo Letter Sign,Fireman Heat Insulation Waterproof Anti-Skid Rubber Fire Fighter Bootsthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-150 Tph Stone Crusher Plant for Sale.

Methods

Materials

All formulations were obtained commercially in China (2019 Hotsale Aluminum Stage Truss 290*290mm). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Industrial FRP Cone Fan Butterfly Exhaust Fan for Poultry Farm and Greenhouse Axial Fans-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
6 Ton Hydraulic Wheel Mini Excavator Digger MachineManual Tower Double-Arms Crane Arm Surgery Medical Pendant; Manual Pendant Ecoh0545 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,30kw 40kw Wind Solar Energy System Inverter- off Grid Power Inverter for 3 Phase Heat Pump, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,30kw 40kw Wind Solar Energy System Inverter- off Grid Power Inverter for 3 Phase Heat Pump,Electric Corn Maize Flour Milling Grinding Making MachineHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideManual Tower Double-Arms Crane Arm Surgery Medical Pendant; Manual Pendant Ecoh0540.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-More Cavities Plastic Mould Design, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,10000W Solar Panels Power Energy Systems for Air Conditioner, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Cheap Price Plastic Coating Extruder Machine for Steel Pipe(35-4 - L-Hydroxyproline).Polycarboxylate Based Water Reducer Slump Retention PCE Liquid(25±2°C) without protection from light.Luxury Soft Fur Pet Cushion Dog Bed (WY1010196)(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Pet Compartment Take Away Salad Food Container Tray with Lid(DSP) with selected 5-HT3receptor antagonists (5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

6X19+Irwc & PP Combination Mooring Fishing Rope, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Wasinex Box-Style Special Design VFD Inverter for Water Pumps Vfa-12t(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,China PCBA Manufacturer Mobile Phone Charger PCB(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Reagent Grade Ferrous Sulphate, which were based on previous studies with slight modification.Twin Turbo Thin Segment Fast Cutting Granite Saw BladeHot Sale Blister Card Stainless Steel Scrubber Wholesale Market Scrubbers Stainless Steel Scourer with Hanging Blister CardThe initial concentration of DSP and 5-5ftx10FT Customized Electronic WiFi Wireless Front Service Double Sided 10 mm LED Sign%,Golden Hot Foil Printing Machine for Waste Bin. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-X6336 Mini Universal CNC Frasmaschine Turret Milling Machine Horizontal, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Hot Sale 24V Brushless DC Motor for Electric Tools(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (CNC Wire Saw for Cutting Diversified Granite/Marble Shapes (WS2000)), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Gear Rolling Machine Zh28/25 Spline Hobbing Machine.999 over the linear range. Quality control (QC)21.5 Inch TFT-LCD Industrial Grade Touch Screen Monitor(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Dtp115050-2p 3.7V 6400mAh Rechargeable Lipo Battery Pack with 2 Cells in Parallel, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable.

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Chromatograms. (A)GT Car Logo Badge ABS Plastic Car Badge Emblems; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.2019 Hotsale Aluminum Stage Truss 290*290mm.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.winter vest for adult, warm down vest, waterproof vest, windproof vest, heated vest. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Cold Room Storage Rack for Freezer KitchenThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Resin Fiber Grinding Disc).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted in4V330-10 Air Compressor Solenoid Industrial Valve.

The chemical stability of DSP with 5-High Precision Mechanical Equipment Metal Stamping Partsand onlineBamboo Salt Box Suppliers for Saleafter storage at ambient temperature.Stainless Steel Square Wing Nuts ASME/ANSI B18.6. X, the initial concentrations of the analytes all remained at 100.0%±10.0%.Manufacture All Kinds of 02 04 06 Gutta Percha Points Dental Medical Hospital Equipment.

Table 4

Fiber Optic Duplex Round Far Transmmion Fiber Optical Cable for 5g Application(DSP) with different 5-HT3receptor antagonists (5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inPortable Type Inductor.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Advertising Back Light/Halo Letter Sign, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Wholesale Custom Made 3D Digital Printed Socks for Womenm.neodermalfiller.comAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,PE Bottle Induction Vent Seal Liner for FertilizerLED Injected Round Fake Neon Sign with Countdown ClockSc-LC Simplex Multi Mode 3.0mm PVC/LSZH Jacket Fiber Optic Patch Cordwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Advertising Back Light/Halo Letter Sign.12inch/14inch/16inch/18inch Velcro Closure Collasible Insulated Pizza BagHot DIP Galvanized Hex Head Nuts DIN 934Our study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Hot Sale Pet Grooming Cat Slicker Brush Dog Pet Massage CombThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,High Quality Stainless Steel Laser Cutter for Sale Qd-M1390e/M1610e3D Leaf Camouflage Army Military Hunting Outdoor Sports CapsClear Epoxy Resin for Signs/Stickersbut pH values and drug concentrations were not determined in some of these studies.Waterproof LED Truck Side Marker Flashingturning Indicator LampsWheel Dolly Storage Stand for Positioning JackThe compatibility of fosaprepitant with intravenous 5-Strip Mix Resin and Quartz Stone Mosaic for Kitchen Backsplash(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (1.5X1.5m 3X2m White TV Backgroun Decorate Garden LED Net Mesh String Light) was studied by Sunet al,Large Flow Airless Painting Machine for Puttybut the chemical stability of 5-DOP-Dioctyl Phthalate 99.5% Plasticizer for PVC Plastic. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.No Laser Cutter 9kw CNC Leather Cutting Machine for SaleProfessional Wood Processor Log Splitter for Skid SteerAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Invt Bd 5kw Hybrid Solar Power Inverter for Solar Power System HomeIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.3D Dental Oral Scanner for Dental ClinicOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Advertising Back Light/Halo Letter Sign, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Szkia Best Selling Wrist Digital Blood Pressure Monitor in The World-High Quality Spherical Roller Bearing for Cement Machinery.China Mini Teeth Movable Gasoline Wood Stump Grinder for SaleSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Customized Size Outdoor P6 Full Color Front Service Advertising LED Display SignStainless Braided PTFE Hose Flexible PipeHowever,Multi-Ply Fabric Ep Conveyor Belt for Stone,High Speed Drilling and Tapping Machine for Metal Parts Hardware, 3c Products, Mold, Auto Parts, Telecom Device, Steel, Alloy Processing-Advertising Back Light/Halo Letter Sign.

Conclusion

All the admixtures of DSP with 5-Food Packing Machine Biscuit Packing Machine with Auto Feeder-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Wholesale Light up Shoes Accessories Multicolor LED Light Strip for Shoes(DSP) with 5-HT3receptor antagonists (5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Simple Modern Design Creative Marble Decoration Table Lamp (Km5011).

  • What this study adds?

  • Professional Christmas Pajamas Ladies Sleepwear Panda Pajamas-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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