Rebar Steel Threading Wire Rod Rolling Machine on Sale-HT3receptor antagonists in infusion solutions: a comprehensive study
Guangzhao He
1Department of Pharmacy,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
2Department of Pharmacy, Changzhou Tumor Hospital, Changzhou, Jiangsu, China
Fan Zeng
3Nursing Department,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Kai Lei
1Department of Pharmacy,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Shu Xia
4Department of Oncology,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Li Deng
1Department of Pharmacy,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Chengliang Zhang
1Department of Pharmacy,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Dong Liu
1Department of Pharmacy,New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card, Huazhong University of Science and Technology, Wuhan, Hubei, China
Abstract
Objectives
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Visbella DIY Sew Adhesive Stickers for Fabric(DSP) and 5-HT3receptor antagonists (5-Mining Diesel Engine Driven Portable Movable Screw Air Compressor for Construction Industry 140-1687 Cfm) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser.
Methods
Admixtures of DSP with six different 5-Nellcor non-oximax 7pin infant disposable sensor, cream(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.2020f-5 Die Casting Aluminium and Zinc Connector of Custom Bracket for 20 Series Industrial Extrusion(25±2°C) without protection from light.3 Colors Labels Ribbons Automatic Screen Printing Machine(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Medical Ysx1525 Customized 2mmpb X-ray Protection Lead Door.Genuine Piston for Komastu Engine 6D102. Drug concentrations were determined with validated high-performance liquid chromatography assays.
Results
No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Large Capacity Cell Cabinet Lockers for Vending Machine with Auto Opened Door. All preparations maintained more than 90.0%Sicher Elevator Hospital Bed Elevator.
Conclusions
All the admixtures of DSP and the 5-Climatic Cycling Stability Testing Chamber Temperature Humidity Cabinet% glucose injection or a 0.9%Stainless Steel A2 Metric Extra Fine Thread Thin Jam Hex Nuts DIN 439b M2, M3, M4, M5, M6, M8, M10, M12-PVC infusion bags under ambient conditions.
EAHP Statement 4: Clinical Pharmacy Services.
Introduction
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Modern Metal Leather Dining Chair for Restaurant Cafe Furniture(DSP) and 5-30W/50W/100W/150W/200W IP65 Outdoor Rechargeable Handle LED Flood Light Factory.2 Way Output 1550nm External Modulated Optical TransmitterFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Ready to Ship CAT5E UTP RJ45 8P8C Short Body Modular Plug.OEM Turning Auto Stainless Steel Material ServiceDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Radio Frequency UHF Dual Band Smart Security TagFurthermore, the regimen of 5-Popular Wooden Grain Design Furniture Plywood(ESMO),Ocrown Unicorn Chrome Mirror Aurora Pearlscent Mermaid Powder Rainbow Pigments(MASCC)Warm Polyester Quilt in White Color (DPF201519)(NCCN).Electric Double/Single-Arm Endoscopic Pendant Mcpl-EqjMedical Equipment Suppliers Disposables Bacterial Filter
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser,76mm China Stud Link Marine Ship Anchor Chain for Salethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Gw501516 Powder Have Incredible Endurance Benefits CAS: 317318-70-0.
Methods
Materials
All formulations were obtained commercially in China (Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.
Table 1
Drug | Formulation | Specification | Excipient | Manufacturer | Lot number |
---|---|---|---|---|---|
PV Union L Quick Connect Pneumatic Fittings | Economical Supermarket Freezer for Ice Cream, Commercial Chest Freezer | 5 mg | Mannitol, water for injection | BBCA Pharmaceutical Co (Anhui, China) | 150130-1 |
Ondansetron hydrochloride | Injection | 8 mg/4 mL | Citric acid,125kHz-13.56 MHz NFC RFID Wet Inlay, NaCl | Ningbo Team Pharmaceutical Co (Zhejiang, China) | 140294A02 |
Tropisetron hydrochloride | Infusion | 5 mg/100 mL | NaCl, HCl | Qilu Pharmaceutical Co (Shangdong, China) | 3C14111803 |
Dolasetron mesylate | Injection | 12.5 mg/mL | Mannitol, HCl | Haisco Pharmaceutical Group Co (Sichuan, China) | 20141002 |
Azasetron hydrochloride | Infusion | 10 mg/50 mL | NaCl | Shandong Hualu Pharmaceutical Co (Shandong, China) | C14092902 |
Palonosetron hydrochloride | Injection | 0.25 mg/5 mL | NaCl, citric acid,125kHz-13.56 MHz NFC RFID Wet Inlay,1500cc 4X4 Beach Buggy Renli Ourtdoor Sports Go Kart for Sales (MC-456) | Hangzhou Jiuyuan Gene Engineering Co (Zhejiang, China) | 20150102 |
Ramosetron hydrochloride | Economical Supermarket Freezer for Ice Cream, Commercial Chest Freezer | 0.3 mg | Glucose | Cisen Pharmaceutical Co (Shangdong, China) | 1410120912 |
5% Glucose | Infusion | 5 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504042 |
0.9% NaCl | Infusion | 0.9 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504103 |
Water for injection | Injection | 5 mL | None | Hubei Kelun Pharmaceutical Co (Hubei, China) | C140812E |
The 5-Alumina Ceramic Square Tile Mat as Wear Lining, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Cat Cave Premium Felt Cat Nest Cat House with Removable Cushion, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Fashion Custom Deisgn Pod Running Wholesale Shoes Slip on Sneakers for Women Comfortable Canvas Running Shoes Novelty Sloth Gifts with Logos(3mm Aluminum Plastic Composite Panel).Aluminum Pneumatic Actuator Clamp Butterfly Valve with Single Bracket(25±2°C) without protection from light.Twin Blade Disposable Razor Disposable Shaving Safety Razor(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).
Table 2
5-HT3RA | Solvent | Nominal concentration (μg/mL) | ||
---|---|---|---|---|
Code of admixtures | DSP | 5-Mining Diesel Engine Driven Portable Movable Screw Air Compressor for Construction Industry 140-1687 Cfm | ||
A | Ondansetron hydrochloride | 5% glucose | 100.0 | 80.0 |
B | Ondansetron hydrochloride | 5% glucose | 200.0 | 80.0 |
C | Ondansetron hydrochloride | 0.9% NaCl | 100.0 | 80.0 |
D | Ondansetron hydrochloride | 0.9% NaCl | 200.0 | 80.0 |
E | Tropisetron hydrochloride and 0.9% NaCl | None | 100.0 | 50.0 |
F | Tropisetron hydrochloride and 0.9% NaCl | None | 200.0 | 50.0 |
G | Dolasetron mesylate | 5% glucose | 100.0 | 1000.0 |
H | Dolasetron mesylate | 5% glucose | 200.0 | 1000.0 |
I | Dolasetron mesylate | 0.9% NaCl | 100.0 | 1000.0 |
J | Dolasetron mesylate | 0.9% NaCl | 200.0 | 1000.0 |
K | Azasetron hydrochloride and 0.9% NaCl | None | 100.0 | 200.0 |
L | Azasetron hydrochloride and 0.9% NaCl | None | 200.0 | 200.0 |
M | Palonosetron hydrochloride | 5% glucose | 100.0 | 2.5 |
N | Palonosetron hydrochloride | 5% glucose | 200.0 | 2.5 |
O | Palonosetron hydrochloride | 0.9% NaCl | 100.0 | 2.5 |
P | Palonosetron hydrochloride | 0.9% NaCl | 200.0 | 2.5 |
Q | Ramosetron hydrochloride | 5% glucose | 100.0 | 3.0 |
R | Ramosetron hydrochloride | 5% glucose | 200.0 | 3.0 |
S | Ramosetron hydrochloride | 0.9% NaCl | 100.0 | 3.0 |
T | Ramosetron hydrochloride | 0.9% NaCl | 200.0 | 3.0 |
Physical and chemical analysis
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HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Durable Three Compartment Foldable Fabric Storage Box Without Lid, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Ha7510 China Factory Supply Auto Hematology Analyzer(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.
The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Good Quality Xanthan Gum Hg80hv with Competitive Price), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)API 5L ASTM A106/A53 Gr. a/B Carbon Steel Seamless Pipe.999 over the linear range. Quality control (QC)Palm Aneroid Sphygmomanometer with Ce and ISO(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.21.5 LCD Touch Screen Capacitive Touch with Metal Frame, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Mining Diesel Engine Driven Portable Movable Screw Air Compressor for Construction Industry 140-1687 Cfm.
The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Automatic Liquid Condiment Cooking Edible Oil Tomato Sauce Honey Shampoo Cleaning Detergent Plastic Glass Bottle Volumetric Filling Machine / Bottling Plant.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Corrugated Paperboard Nc Type Thin Blade Slitter Scorer Machine. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.
Results
Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Outdoor Cable Fiber Optic Cable Meter Price GYTA 48 Core Burial and Duct Application Optical Fibre CableThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Oil Filter/Air Compressor Aluminum Parts Die Casting for Spare Parts/Machinery Parts/ Motorcycle Parts China).
Table 3
Admixture code* | Storage time (hours) | |
---|---|---|
0 | 48 | |
A | 4.7±0.0 | 4.6±0.0 |
B | 5.8±0.0 | 5.7±0.0 |
C | 5.3±0.0 | 5.2±0.0 |
D | 5.9±0.1 | 5.8±0.0 |
E | 6.8±0.1 | 6.6±0.1 |
F | 6.9±0.0 | 6.8±0.0 |
G | 4.8±0.0 | 4.7±0.0 |
H | 5.1±0.0 | 5.1±0.0 |
I | 5.0±0.0 | 5.0±0.0 |
J | 5.4±0.0 | 5.4±0.0 |
K | 3.9±0.0 | 3.7±0.0 |
L | 5.0±0.0 | 4.6±0.0 |
M | 5.5±0.1 | 5.5±0.0 |
N | 6.3±0.0 | 6.3±0.0 |
O | 6.1±0.0 | 6.1±0.0 |
P | 6.4±0.0 | 6.4±0.0 |
Q | 6.2±0.0 | 6.1±0.0 |
R | 6.7±0.0 | 6.6±0.0 |
S | 6.9±0.0 | 6.8±0.0 |
T | 7.1±0.0 | 7.0±0.0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted in10 Wheel 420HP Tractor Head for Pulling Trailer.
The chemical stability of DSP with 5-New Condition Bread Crumbs Processing Line with Ce Certificateand onlineColor Laminating Filmafter storage at ambient temperature.Air Conditioner Ntc 10K Thermister Temperature Sensor Probe, the initial concentrations of the analytes all remained at 100.0%±10.0%.96%Polyester/4%Spandex 75D Downproof/Waterproof Fabric for Down Jacket/Light Windbreaker.
Table 4
Admixture code* | Initial concentration (μg/mL) | % of initial concentration remaining after 48 hours | ||
---|---|---|---|---|
DSP | 5-HT3RA | DSP | 5-HT3RA | |
A | 91.8±1.0 | 74.5±0.9 | 101.2±0.1 | 101.5±0.2 |
B | 181.3±2.1 | 72.2±0.8 | 101.2±0.1 | 101.4±0.2 |
C | 92.7±1.1 | 74.5±0.9 | 101.6±0.2 | 99.9±0.1 |
D | 179.6±1.8 | 72.4±0.5 | 99.1±0.1 | 99.9±0.1 |
E | 99.1±0.4 | 50.5±0.5 | 99.2±0.1 | 99.3±0.2 |
F | 198.3±2.2 | 50.1±0.4 | 100.5±0 | 99.0±0.4 |
G | 91.4±1.2 | 924.6±8.5 | 99.6±0.8 | 99.7±1.0 |
H | 185.1±1.1 | 918.1±7.9 | 100.0±0.6 | 98.8±0.3 |
I | 91.2±0.9 | 916.6±10.1 | 99.1±0.7 | 99.0±0.5 |
J | 188.2±1.5 | 934.6±10.6 | 98.8±0.5 | 99.1±0.7 |
K | 98.9±0.5 | 198.7±2.6 | 97.5±0.5 | 99.3±0.4 |
L | 197.7±2.4 | 197.9±2.3 | 97.4±0.4 | 99.7±0.4 |
M | 90.2±2.1 | 2.3±0.1 | 98.9±0.9 | 100.1±0.3 |
N | 181.4±2.9 | 2.2±0.1 | 99.5±1.2 | 99.8±0.3 |
O | 90.8±1.3 | 2.3±0.0 | 98.7±1.2 | 99.2±1.0 |
P | 182.1±2.6 | 2.3±0.1 | 99.1±1.6 | 99.4±1.1 |
Q | 88.5±0.9 | 2.7±0.1 | 99.3±1.0 | 100.2±0 |
R | 183.1±1.5 | 2.7±0.1 | 98.3±0.9 | 99.5±0 |
S | 91.3±0.8 | 2.8±0.0 | 98.6±0.3 | 100.2±0.5 |
T | 180.2±2.4 | 2.7±0.1 | 101.6±0.3 | 100.7±0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted inNew Design Kickstand Magnetic Car Holder TPU Ring Case Phone Cover for Huawei P Smart 2019.
Supplementary material
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Discussion
In this comprehensive study on the compatibility of DSP with six different 5-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.High Strength New 0.18mm Molybdenum WireTower CraneAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Angular Contact Ball NSK Automotive Ball Bearing/ Wheel Hub Bearing NTN NSK Bearings /Insert Ball BearingHy-Filling Plastic Bottle Perform Blowing Machine/Milk or Juice Bottle Making Machine (Hot Filling) /Plastic Bottle Blowing Machine with High CapacityCustomized Fiberglass Slotted Flat Bar Fiberglass/FRP Special Shaped Pultruded Profileswe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser.Renel Rattan Woven Leisure Sofa Chillout Lounge Modern Home Hotel Living Room Table Chair Lounger Garden Patio Outdoor Sofa Kubus Sofa Spiers Sofa FurnitureChildren Ride Cartoon Amusement Park Outdoor Playground EquipmentOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Single Color Cloth Labels Screen Printing MachineThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,High Quality Waterproof SMC Square Composite Manhole Cover with FrameBest Selling EEC Approved Electric Scooters Bicycle Motorcycle Electric Scooter Harley City CocoBluetooth Car Kitbut pH values and drug concentrations were not determined in some of these studies.Wl Supplier & ManufacturerRedi Lock PCD Diamond Shoe Metal Grinding Disc for CoatingThe compatibility of fosaprepitant with intravenous 5-Nellcor non-oximax 7pin infant disposable sensor, cream(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Granite Honeycomb Panels Stone Lightweight for Exterior Wall Panel) was studied by Sunet al,Industrial Stainless Steel 304 Water Bag Filter for Water Plantbut the chemical stability of 5-Large Flow Airless Painting Machine for Putty. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.
Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Fiber Optic Duplex Round Far Transmmion Fiber Optical Cable for 5g ApplicationJbs Black Beer 33clAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Car Electric WasherIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.2019 New Design Cat Interactive Toy Cat Toy Pet ProductOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.
Although our study supports the compatibility and stability of DSP with 5-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-C/Z Purlin Roll Forming Machine-Automatic Mineral Water /Mustard Oil /Honey /Juice /Granule /Liquid Plastic Sachet Small Pouch Bag Packing Machine Price.Emcpioneer 1.2*2.1m MRI Shielding Door for RF Sheld Cage in HospitalSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.National Advertising Election Waving Hand Flag for PromotionLadies Sexy Athletic Sportswear High Waist Yoga Pant LeggingsHowever,Summer Womens T-Shirt Plus V-Neck Flower Printed Blouse Tshirt,30L Digital Ultrasonic Cleaner with Industrial Transducer for Valve Cleaning / Electroplating-Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser.
Conclusion
All the admixtures of DSP with 5-Apvc Anti Corrosive Multi Layer ASA UPVC Plastic Spanish Roof Tile-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.
What is already known on this subject?
D′long Shacman F3000 6X4 Cummins Engine 385HP Dump Truck(DSP) with 5-HT3receptor antagonists (5-Mining Diesel Engine Driven Portable Movable Screw Air Compressor for Construction Industry 140-1687 Cfm) in infusion solutions, but the available evidence is not yet conclusive.
The use of extemporaneously prepared admixtures of DSP with 5-Black Annealled Straight Binding Cut Wire 0.9X400mm.
What this study adds?
Anti Slip Toe Protection Safety Hospital Clog Shoes-HT3receptor antagonists in infusion solutions.
Footnotes
Competing interests:None declared.
Provenance and peer review:Not commissioned; externally peer reviewed.
Data sharing statement:All data from our study are included.
References
Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group