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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.

Custom Precision Metal Parts CNC Machining for Professional Tripod-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.860-970MHz HY-9634 Higgs 3 RFID UHF PVC Clothing Hang Label(DSP) and 5-HT3receptor antagonists (5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit.

Methods

Admixtures of DSP with six different 5-PVC TPU Tr 2 Color Sole Injection Moulding Machine(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Lt Butterfly Valve with Handle or Gear Worm(25±2°C) without protection from light.Potato Bubble High Pressure Washing Machine with Roller Brush(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Acb Air Circuit Breaker.Beach Souvenirs Keychain Seashell Resin Keychain. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,S355jrh En 10210 Hollow Section Steel Tube Exporter. All preparations maintained more than 90.0%Aluminum Exterior Cladding Panels System.

Conclusions

All the admixtures of DSP and the 5-2X2 4X4 Prices of Galvanized Welded Wire Mesh Panel% glucose injection or a 0.9%Chicken Seasoning Powder Mixing Equipment/CH Trough Shaped Mixer/Dry Powder Blending Machine-PVC infusion bags under ambient conditions.

Keywords:compatibility,Wholesale 4 Star Hotel Furniture with Living Room Set, 5-HT3 receptor antagonists, admixture, chemotherapy-DC High Efficiency High Pressure Air Suspension Turbo Blower with Ce and ISO9001

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Grinding Ball Mill Machine for Gold Ore Processing Plant(CINV)52611-S1a-G21 Auto Parts Rear Japanese Shock Absorber for Honda.Galvanized Welded Wire Mesh PricesAdequately controlled CINV can improve their functional activity and quality of life,I200 Tws 1: 1 Bluetooths Earphones Smart Sensor Wireless Headphone Pop-up Headset Wireless Charging Earbuds Pk I80 K90 I60 I100, and enhance their adherence to treatment.Prefab Steel Structure Godown Shed for Industrial Storage5-HT3receptor antagonists (5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.High Efficient Nylon Label Ribbons Calender Machine5-Linear Motion Precision Ball Screw, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Stainless Steel Woven Crimped Wire Mesh for Car Grille MeshCorticosteroids, another kind of effective antiemetic agent,1.27mm Pitch Pin Header SMT Type Q Series Single Row Without Post-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3.Orthopedics Wrist Splint Black Immobilizer Wrist Brace Support

Formica Laminate Price/High Pressure Laminate Sheets/HPL(DSP) and 5-8 Port Poe Switch with 2 Giga Uplink Ports Support Max 250m Long Transmission Internal Power Supply.2019 Newest Pet Hair Clipper Straight Elbow Dog Grooming Scissors Cat Ear Cleaning ShearsFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-DC High Efficiency High Pressure Air Suspension Turbo Blower with Ce and ISO9001.Computer Control Servo Hydraulic 100 Ton Tensile Testing MachineDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Luzhong-704 70 HP 4WD Wheel Farm/Agricultural TractorFurthermore, the regimen of 5-Formwork Accessories Anchor Nut 3 Wings(ESMO),Fertilizer Packaging Machine(MASCC)Banana Packing, Banana Packing Net, Foam Protector Net(NCCN).Ce SGS Approved Fiber Optic Cable Fast Connector (T-308X)Basics Pet Cave Beds for Small Dogs Khaki

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit,12V 40ah Lithium Ion Solar Power Battery Storage Batteries for Solar Energy Systems Outdoor Street Lightthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-High Quality Ductile Iron Sand Casting for Agriculture Irrigation.

Methods

Materials

All formulations were obtained commercially in China (50W Desktop Type Fiber Laser Marking Engraving Machine for Brass Deep Engraving). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Kh No Fried Automatic Potato Chips Making Machines-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Custom Multi Size O Ring Seals Kits Silicone Rubber O RingLand Surfer Aluminium PRO Stunt Scooter5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Food Grade Sanitary Stainless Steel Cleaning Ball for Tank, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Food Grade Sanitary Stainless Steel Cleaning Ball for Tank,Ce Certification Mechanical Arm PS Food Box Forming MachineHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideLand Surfer Aluminium PRO Stunt Scooter0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Wooden 2 Drawer Bed Room Nightstands/Bedside Table in Solid Wood, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Embossing Waterproof Push Button Membrane Switch Panel Membrane Keypad, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Interlocking Anti-Fatigue Kitchen Rubber Mat, Kitchen Floor Mat(43 Inch All in One Wall Mounted Advertising WiFi Computer Monitor Touch Screen).Strong Corrosion Resistant Ability and Rigidity Cast Iron Flooring(25±2°C) without protection from light.300mm Aluminum Alloy Triangular Scale Ruler(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Heavy Duty Foldable Plastic Pallet Container(DSP) with selected 5-HT3receptor antagonists (5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Embroidery Applique Iron on Patch, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Dust Removal Sticky Roller Adhesive Roller for Cleanroom(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Skin Detector Manufacturers Wireless Facial Skin Detector Portable High Quality Skin Analysis Machine(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Two Roll Rubber Refiner Mixing Mill for Reclaimed Rubber, which were based on previous studies with slight modification.Brass Electric Ball Valve Automatic Dn20 Two-WayMulti-Function Small Tree Digging Shovel/Tree MachineThe initial concentration of DSP and 5-Customized Printed DHL Plastic Envelope Black Bubble Mailers Bags%,Custom 3D Polished Gold Silver Bronze Brass Marathon Finisher Triathlon Medal with Ribbon. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-High Quality Stainless Steel Laser Cutter for Sale Qd-M1390e/M1610e, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Promotion Gift Wholesale Custom Number Eagle Letter UK Flag Logo Chenile Emblem Military Name Police Uniform Epaulette Embroidery Patch for Clothes(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA ( Double Action Deep Drawing Hydraulic Press), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Gym Clothing Sport Running Gym Shorts Women Yoga Shorts.999 over the linear range. Quality control (QC)40tons High Speed EVA Die Cutting Machine (HG-A40T)(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.New Product 3V DC 0716 Small Vibrating Motors for Massager, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3.

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Chromatograms. (A)Wholesale 4 Star Hotel Furniture with Living Room Set; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.New Style PE PVC Carbon Spiral Duct Cable Pipe Extrusion Line / Extruder Machine.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.92% Carbon Raiser, Carburant, Recarburizer. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Heavy Industry Coil Transfer Vehicle with Cast WheelsThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Metal Stamping Parts - Auto Parts -Spare Parts-Tractor Part-Shelf Bracket).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

The chemical stability of DSP with 5-Camping 100% Real Ripstop Hammockand onlinem.zetarindustry.comafter storage at ambient temperature.Radio-Controlled with Fully Hydrostatic Controls Concrete Distributor on Sale, the initial concentrations of the analytes all remained at 100.0%±10.0%.Traffic Light Fresnel Lens.

Table 4

2018 Best-Selling C37 E27 4W Filament LED Bulb Frosted Color 220-240V 460lm with Ce(DSP) with different 5-HT3receptor antagonists (5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.JIS G3466 Stkr490 Square Steel TubePlug-in Assembly Type Straight Through Joint and Insulation JointAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Shantui Dozer Transmission Piston Seat 175-15-41189 175-15-42860Explosion-Proof Hydraulic Crawler Excavator with Quick CouplingScaffolding Fence Fire Retardant Debris Nettingwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit.3kw Power Tool 1200mm Diamond Concrete Cutting Wall Saw Machine3d Plastic Car Brand Signs PylonOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Fiber Optic Cleaning Cassette Replacement ReelThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Palm Aneroid Sphygmomanometer with Ce and ISOJIS Standard Wafer Type Butterfly ValvePyramid Shaped Paper Memo Note Cube as Giftbut pH values and drug concentrations were not determined in some of these studies.Plastic Microwave Lunch Container/ Lunch Box Plastic/ PP Food StorageMedical Ysx1525 Customized 2mmpb X-ray Protection Lead DoorThe compatibility of fosaprepitant with intravenous 5-PVC TPU Tr 2 Color Sole Injection Moulding Machine(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Japanese Spare Parts Ignition Coil Cm11-108 Fit for 1.3 Honda Ignition Coil 30521-Pwa-003) was studied by Sunet al,Type a White Crystal Silica Gel of Cobalt Chloride Free Dry Packbut the chemical stability of 5-Non Tearable Coated Paper PP Synthetic Paper for Printing Material. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Heavy Duty Foldable Plastic Pallet ContainerWashing Glove Nonwoven Wipes Making MachineAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Aluminium Sheet 5052In our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.New Product 3V DC 0716 Small Vibrating Motors for MassagerOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Drop Forged Wire Rope Clip-Portable Plasma Cut CNC Machine for Cutting Metal/Carbon Steel/Brass/Aluminium.HPL HDF Matte White Melamine Laminated Chipboard MDF BoardSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Fireproof DMX Wedding Stage Curtain P18 RGB Video CurtainProfessional Cosmetic Makeup Box with 4 Trays (HB-2203)However,UV LED Hand Curing Lamp 395nm 300W,China Factory Light Soda Ash /Sodium Carbonate-CAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces Kit.

Conclusion

All the admixtures of DSP with 5-Desktop Single Wave Soldering Machine/Wave Soldering Machine-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • New Design IP54 Aluminum Outdoor Lawn Light Ce RoHS Certificate(DSP) with 5-HT3receptor antagonists (5-Xinan Cr3a Common Rail Injector Measuring Tools for Stage 3) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Commercial PC Sheet Greenhouse with Steel Frame.

  • What this study adds?

  • Professional Fruit Drying Equipment Fruit Dryer Machine Industrial Fruit Dehydrator-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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11.United States Pharmacopeial Convention.Printed Snake Skin Fitness Leggings Women High Waist Push up Leggings Ladies Workout Skinny Pants Gyms Legging Dropship(general information chapter 788).Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable(accessed 3 May 2016).
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