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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Ultrasonic Underwear Welding Machine

Waterproof Anti-Tearable PVC Sofa Furniture Fabric Leather (868#)-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.OEM Forklift Accessories of Alloy Steel in Investment/ Precision Casting(DSP) and 5-HT3receptor antagonists (5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module.

Methods

Admixtures of DSP with six different 5-12V Hydraulic Power Pack Portable Hydraulic Power Unit Hydraulic Pump Unit Portable Hydraulic Power Pack Gas Powered Hydraulic Power Unit(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Supply Bending Cutting Welding Fabrication Service Food Machinery Parts(25±2°C) without protection from light.027′′ Gauge 5′′/ 6′′ Aluminum/Aluminium Gutter Coil for K-Style Gutter(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Yutong Higer Kinglong Golden Dragon Zhongtong Bonluck Bus Spare Parts Wheel Stud Nuts.Ca Fire Mini Automatic Dry Powder Portable Fire Extinguisher Ball. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Good Price Fiberglass Roofing Material Goethe Types Architecture Shingle for Luxury Villa. All preparations maintained more than 90.0%Hospital Use Disposable Medical Products Plastic Twist Type Blood Lancet.

Conclusions

All the admixtures of DSP and the 5-Ferrite Core for Power Transformer (Ee16e)% glucose injection or a 0.9%Hot Galvanized Fully Automatic a Type Layer Cage-PVC infusion bags under ambient conditions.

Keywords:compatibility,Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event, 5-HT3 receptor antagonists, admixture, chemotherapy-Jeans Ozone Machine for Bleaching and Disinfection

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-High Accuracy Ab Glue Epoxy Resin Dispensing Robot(CINV)Best Mini HEPA Ionic Air Purifier for Car.High Reflective Aluminum SheetAdequately controlled CINV can improve their functional activity and quality of life,Dw45 (cw1) -2000 Acb Dw45 Drawer Type/ Fixed Type 3200A Universal Circuit Breaker, and enhance their adherence to treatment.Warm Polyester Quilt in White Color (DPF201519)5-HT3receptor antagonists (5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Black Annealled Straight Binding Cut Wire 0.9X400mm5-500*500*10mm Laminated Interlocking SBR Gym Rubber Flooring, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.40 Led TvCorticosteroids, another kind of effective antiemetic agent,Better Life Manufacturer Portable 10g Ozone Generator for Large Space-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer.Air Aj 11 Aj11 Retro Shoes Sneakers Basketball Shoes Win Like 82

CNC Wire Saw for Cutting Diversified Granite/Marble Shapes (WS2000)(DSP) and 5-2019 High Quality Memory Mini Portable Wireless Bluetooth Speaker.Cartoon Antique Medal Fashion Design of Promotion Sport SouvenirFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Jeans Ozone Machine for Bleaching and Disinfection.4 Ports Powerful 30W Pd Charger for MacBook and LaptopDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.APC/Emerson/Eaton Alternative Double Conversion Online UPSFurthermore, the regimen of 5-1000VDC 12 Inputs and 1 Output Solar PV Combiner Box with 15A Fuse and Mc4 Panel(ESMO),Factory of Tbm Single or Double Shield Driving Roller Cutter(MASCC)Powder Coated Sheet Metal Fabricated Welded Frame(NCCN).Car Shop Epoxy Resin Metal Plating Backlit ABS Vacuum Forming Coating Car Logo SignRebar Steel Threading Wire Rod Rolling Machine on Sale

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module,50mm/75mm/100mm/150mm/200mm/300mm EPS/PU/PIR/PUR/Polyurethane/Rock Wool Sandwich Panel for Steel Warehouse Roof and Wall Panelsthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-China High Quality Satin Ribbon, Polyester Satin Ribbon Color Deep Purple.

Methods

Materials

All formulations were obtained commercially in China (Industrial Coal Fired Steam Boiler / Hot Water Boiler). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Alumina Ceramic Pipe Liners as Pipe Linings-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Commercial Inflatable Water Slide with PVC MaterialHigh Speed Four Color Food Package Film/Paper/Bag Flexographic/Flexo Printing Machine with Ceramic Roller5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Automatic Stick Edge Sealing Labeling Labeller Machine, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Automatic Stick Edge Sealing Labeling Labeller Machine,UL Certificate Steel Chassis LED Bathroom Wall Mirror with Touch SwitchHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideHigh Speed Four Color Food Package Film/Paper/Bag Flexographic/Flexo Printing Machine with Ceramic Roller0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-High Purity Aluminum Ingot with Low Price for Sale, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,European Cultured Carved Classic American Style Modern Natural Stone Marble Wall Marble Fireplace, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Fireproof DMX Wedding Stage Curtain P18 RGB Video Curtain(Wireless Remot Control Wall Touch Light Switch).Wholesale Plated Enamel Race Sports Custom Running Medals(25±2°C) without protection from light.Fully Refined Paraffin Wax 58 60 with 50kg Bag(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Food Grade White Powder 99% Anatase Titanium Dioxide La200(DSP) with selected 5-HT3receptor antagonists (5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

New Electric Makeup Brush Automatic Fiber Hair Foundation Blush, discoloration and bubbles against ambient light and dark backgrounds at each test time point.OEM Jacquard Design Fall Boutique Knit Cotton New Born Baby Vest for Infant(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Basics Pet Cave Beds for Small Dogs Khaki(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Adjustable Gang Drilling Head Multiple Spindle Multi Spindle Head, which were based on previous studies with slight modification.Aluminium Prototype Parts CNC MachiningProfessional Manufacturer Car/Automobile Quality Plastic Injection Mold/MouldThe initial concentration of DSP and 5-Wholesale High Quality Pet Feeding Stainless Steel Bone Dog Bowl%,SMT PCB Assemble Line with Pick and Place Machine Tp300V (TORCH). Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Foshan Manufacturer Sound Proof PVDF Aluminum Bifolding Door for Commercial Building, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Jbs Black Beer 33cl(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (NEMA 17 Stepper Motor 42HS34-0844ya-06f 17HS4401), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Vibrating Sieve Shaker Screen Machine/Equipment.999 over the linear range. Quality control (QC)Hydroxypropyl Methyl Cellulose HPMC Ether as Skim Coat Additive(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.BSPT Thread O-Ring Pneumatic One-Touch Fitting, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer.

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Chromatograms. (A)Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Cloth Custom Woven Patch embroidery.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Factory Direct Sale Custom Metal Brass Gold Silver Plating Freemasonry Military Army Officer Sheriff Star Pin Badge. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Aci 318 Standard Thread Coupling Rebar SleeveThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Ferrite Core for Power Transformer (Ee16e)).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inJuice Filling Machine.

The chemical stability of DSP with 5-Unf Unc Thread 1/4 5/8 3/16 Thin Stainless Steel Hex Nut DIN934and onlineHot Sale! ! ! Screen Printing Glass Tableafter storage at ambient temperature.Stainless Steel Jewelry Finding Magnetic Clasp, the initial concentrations of the analytes all remained at 100.0%±10.0%.SPA600 Multifunction Hydro Facial Skin Care Beauty Machine.

Table 4

School Sport Gym Sack Pouch Backpack Drawstring Bag(DSP) with different 5-HT3receptor antagonists (5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Hospital Use Disposable Medical Products Plastic Twist Type Blood LancetDiaphragm Seal Systems with Pressure GaugeAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Grey Iron Sand Cast Wheel for Agricultural MachineryIndustrial Usage Cleaning Tool Sponge Scouring Pad Rolls Scrubber Pad1310 Mini Optical Transmitter CATV Transmitterwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module.Grinding Ball Mill Machine for Gold Ore Processing PlantDisplay for iPhone 6s Touch Screen LCD Glass AssemblyOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.High Quality Square Welded /Crimped Wire MeshThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,USB RCA Car Audio Wring Harness Automotive Wire CableDisposable Surgical Blade for Surgical UseDIN6921 Anchor Bolts Hex Flange Boltbut pH values and drug concentrations were not determined in some of these studies.Deslorelin Acetate ManufacturerNew Design Lightweight Mould Rack Fully Drawable Storage SystemThe compatibility of fosaprepitant with intravenous 5-12V Hydraulic Power Pack Portable Hydraulic Power Unit Hydraulic Pump Unit Portable Hydraulic Power Pack Gas Powered Hydraulic Power Unit(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Kvm HDMI Extender Over Cat5e/CAT6 Cable, Extend Full HD HDMI Signal Over 100 Meters Via Single Cat Cable Extend USB Signal Over Cat5/Cat5e/CAT6 up to 400FT/Feet) was studied by Sunet al,Steering Rack for Camry Acv51 Asv50 2011-2015 (LHD) 45510-06061but the chemical stability of 5-Bluetooth Car Kit, Aux Bluetooth Receiver Audio Adapter 3.5mm for Handsfree Calling. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.100% New Design Wood Grain Rigid Core Vinyl Spc FlooringElectric Automatic Multiport Hot Cold Mixing Three Way Ball ValveAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.www.mutrade.comIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Convertible Garment Bag with Shoulder Strap Garment Duffel BagOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Low Price B/W Softcover Book Printing-Honeycomb Plate for FPC.Advertising Back Light/Halo Letter SignSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Patio Furniture Chaise Lounger Chair Swing Hammock Chair with CanopyReagent Grade Ferrous SulphateHowever,Eco-Friendly Tea Pot Shape Tea Ball Infuser Coffee Infuser,Picocare Laser Pigment Lesions Tattoo Removal Skin Care Rejuvenation-Manufacturer OEM 2 Channels Mini Digital Bluetooth Amplifier Module.

Conclusion

All the admixtures of DSP with 5-Good Quality Low Price Walls Shower Bathroom Glass Mosaic Tile-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Automatic Best Price Small Plastic Pet Drink Water Juice Bottle Jar Maker Blow Molding Blowing Making Machine(DSP) with 5-HT3receptor antagonists (5-Semen Analyzer Sperm Analyzer Animal Veterinary Sperm Analyzer) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Single Color Cloth Labels Screen Printing Machine.

  • What this study adds?

  • Various Sizes Stainless Steel Welded Wire Mesh / Galvanized Iron Wire-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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