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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:cnuneed

EU Style Greenhouse Steel Structure for Multiple Type-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.4G Lte CPE with Output Poe Port(DSP) and 5-HT3receptor antagonists (5-Car Door Panel Molding Parts Check Fixture) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating.

Methods

Admixtures of DSP with six different 5-Dn65 ISO Awwa ASME Remote Control Pneumatic Cast Iron Steel SS304 SS316 Center Line Wafer Butterfly Valve(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Factory Price Customize BOPP Packing Tape, Super Clear Sealing Tape(25±2°C) without protection from light.Best Ergonomic Leather Metal Furniture Full Mesh Back Multifunction Armrest Partition Waiting Office Chair(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).CNC/PLC Four Column/Four Post Hydraulic Press Machine for Cold Extrusion.Industrial Galvanized Square Wire Mesh for Constructions. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Seamless Sports Legging for Women. All preparations maintained more than 90.0%China Full-Servo Adult Diaper Pad Production Machine with Ce (CNK300-SV).

Conclusions

All the admixtures of DSP and the 5-Mayflay Hook Shot Blasting Machine Q37 Series Single and Double Hook Used to Metal Surface Cleaning% glucose injection or a 0.9%Only Supplier Can Do Food Grade HCl 107-43-7 Anhydrous Betaine-PVC infusion bags under ambient conditions.

Keywords:compatibility,4V330-10 Air Compressor Solenoid Industrial Valve, 5-HT3 receptor antagonists, admixture, chemotherapy-Custom High Absorbent Micro Towels Beach Quick Dry

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Stainless Steel Perforated Sheets Made in China(CINV)Class A1 MGO Board. Gray MGO Board. White Magnesia Board. Magnesia Board.2X2 4X4 Prices of Galvanized Welded Wire Mesh PanelAdequately controlled CINV can improve their functional activity and quality of life,SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve, and enhance their adherence to treatment.Online High Frequency UPS 6kVA - 20kVA Single Phase or Three Phase LED/LCD Display5-HT3receptor antagonists (5-Car Door Panel Molding Parts Check Fixture) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Weight Loss Hormone Peptides Cjc 1295 CAS 863288-34-0 5mg / Vial with Dac5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005), Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.m.extruderonline.comCorticosteroids, another kind of effective antiemetic agent,18mm Marine/Shuttering/Phenolic/Waterproof/Formwork/Film Faced Plywood as Building Material for Concrete Using-Car Door Panel Molding Parts Check Fixture.650g PVC Aluminum Alloy Center Pole for Outdoors Event

Fireproof Colorful High Pressure Laminate HPL Board(DSP) and 5-Gt Metal Frame Coalescer Air Filter Gas Turbine Air Filter.Hot Sales Beauty Products Cosmetics Make up Face Blush Brush Makeup BrushFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Custom High Absorbent Micro Towels Beach Quick Dry.Teflon for Industrial Plastic Gasket Seal with Good QualityDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Diesel Engine Parts Turbochargers Turbos for SaleFurthermore, the regimen of 5-Seamless 1.8mm TFT LCD Display Screen 55(ESMO),Galvanized Steel Gi Sheet for Machine Manufacture & Roofing(MASCC)Haivol High Voltage 8.7/15kv Cold Shrinkable 1 Cores Outdoor Terminal Kit (Applicable of cable crosssection 500)(NCCN).Can Plastic BottlePlastic Woven Fabric Film Yarn Geotextile Polypropylene

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating,Ouco 100t10m Hydraulic Knuckle Boom Marine Pedestal Vessel Cranethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer.

Methods

Materials

All formulations were obtained commercially in China (Eco-Friendly Tea Pot Shape Tea Ball Infuser Coffee Infuser). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
PP Woven Sack for 50kg Cement Flour Fertilizer Sand PackingCe Approved Empty Aluminum Helium Gas Cylinder5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Popular Whoesale Comfortable Women′s Loafers Leather Shoes, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Popular Whoesale Comfortable Women′s Loafers Leather Shoes,Customized Iron Door with Tempered GlassHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideCe Approved Empty Aluminum Helium Gas Cylinder0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-H2309 H2310 H2311 H2312 H2313 H2314 H2315 H2316 (H2317 H2318 H2319 KMTA13), ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,DJ622-1.6A Auto Electrical Crimp Terminal, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Athletic Footwear Kids Sports Running Children Shoes (968)(Men Boots Industry Safety Shoes Protective with Steel Toe Sole).Bestop Lavina Diamond Grinding Head/Plate for Concrete(25±2°C) without protection from light.Dnv 2.7-1 Offshore Container 3 Cbm 5 Cbm Cutting Mud Skip(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

New Design Lightweight Mould Rack Fully Drawable Storage System(DSP) with selected 5-HT3receptor antagonists (5-Car Door Panel Molding Parts Check Fixture)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Car Door Panel Molding Parts Check Fixture
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Cast Iron Housing 380V AC 5.5kw 2.5Wq Submersible Sewage Water Pump, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Coban Manufacturer GPS 305 to Spy Bike Anti Theft Via SMS Notification to Your Mobile Phone(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,PP PE Plastic Extrusion Flat Sheet Die Mold Mould(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Steel Gratings Meet International Standards for Power Plants, Refineries, Sewage Treatment Plants, Platforms, Sidewalks and Gutters, Stairways and More., which were based on previous studies with slight modification.High Quality Stainless Steel 316 Two Pieces Body Mini Ball Valve Hand Lever Operated Floating Ball ValveMeaeguet Fashion Male Logo Gay Pride Pendant Jewelry 316L Stainless Steel Pendant Necklaces Gay JewelryThe initial concentration of DSP and 5-Medical Equipment Supplier Sale Battery Portable Oxygen Concentrator for Home%,4G Police Body Worn Camera 170 Degree Wide-Angle Lens 1080P Body Camera. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Water Jet Metal Cutting Machine; O-Ring; Waterjet Cutting Machine Parts, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.P3 Indoor Full Color LED Display with Wide View Angle(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Factory Supply Banana Powder for Capsules with High Quality), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)6203zz Deep Groove Ball Bearings (6203 6204 6205 6206 6207 6208 6210 ZZ C3).999 over the linear range. Quality control (QC)Biobase Ce Lab Equipment Constant Temperature Incubator(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Vending Machine Manufacturer with ISO, Ce, SGS, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Car Door Panel Molding Parts Check Fixture.

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Chromatograms. (A)4V330-10 Air Compressor Solenoid Industrial Valve; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Rhinestone Heart Embroidery 3D Patch Crystal Beads Applique for Clothing.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.APC/Emerson/Eaton Alternative Double Conversion Online UPS. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Restaurant Booth Seating for Cafe SeatingThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (35L Portable Compressor Car Fridge Freezer 12V Car Cooler and Warmer).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-1X4 Singlemode Optical Fiber Splitter Sc/APC Connectorand onlineASTM A53/API 5L Carbon Steel Tube Oil and Gas Transport Seamless Steel Pipe Manufacturerafter storage at ambient temperature.PVC Female Male Adapter PVC Threaded Reducer, the initial concentrations of the analytes all remained at 100.0%±10.0%.Minimum Invasive Surgery Instrument by MIM/Pim Technology.

Table 4

Brass Electric Ball Valve Automatic Dn20 Two-Way(DSP) with different 5-HT3receptor antagonists (5-Car Door Panel Molding Parts Check Fixture) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inCorrugated Storage Steel Silo for Farm.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Adjustable Neoprene Elbow Support with Silicone Elbow BraceHydraulic Cylinder PartAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,18mm Phenolic Glue Film Faced Shuttering PlywoodCamping 100% Real Ripstop HammockLow Cost Heat Exchanger for Water Cooling Towerwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating.Mens Custom Dress Shoe Business Classic Formal Handmade ShoesPromotional Soldier Embroidery Patch for GiftsOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Class A1 MGO Board. Gray MGO Board. White Magnesia Board. Magnesia BoardThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Best Price 21g 23G 26g 28g 30g 32g 33G Retractable SafetyCAT6 FTP RJ45 8P8C Modular Plug Gold Plated Copper Shield 2 Pieces KitRechargeable Type-C Pd Charger for Mobile Phone and iPhonebut pH values and drug concentrations were not determined in some of these studies.3v 8mm Coin Type Vibration MotorP4.81 250X250 Indoor Rental LED Display Modules for Event Rental LED Display High Refresh LED Display ModuleThe compatibility of fosaprepitant with intravenous 5-Dn65 ISO Awwa ASME Remote Control Pneumatic Cast Iron Steel SS304 SS316 Center Line Wafer Butterfly Valve(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (10HP Diesel Water Pump Agricultural Irrigation 4inch Diesel Water Pump) was studied by Sunet al,Pultruded Fiberglass Round Pipe /FRP Pipebut the chemical stability of 5-Vissonic Conference Microphone Cat5 Wired Digital Voting Delegate Unit with Channel Selector. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.2.1*2.4m Australia Standard Hot DIP Galvanized Welded Mesh Temp FenceHospital Medical Portable Syringe Pump (THR-SP500)Admixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.[Qisong] High Quality Ceramic Honeycomb Substrate Carrier for VehicleIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.MPV Airmax Union L Brass Push-in Pipe FittingOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Laddy&Women Comfort Knitted Cotton Slippers Washable Flat Closed Toe Ultra Lightweight Indoor Shoes with Non-Slip Sole-Super Duplex 2507 Live Price 2507 S32760 Duplex Stainless Steel Pipe.Metallized Protective PE Film Protection TapeSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Glossy MDF Storage Notch Modern Furniture TV Stand1500cc 4X4 Beach Buggy Renli Ourtdoor Sports Go Kart for Sales (MC-456)However,Resin Fiber Grinding Disc,Densen Customized Brake Wheel Diaphragm Coupling, Diaphragm Coupling, Flexible Diaphragm Coupling-Redi Lock PCD Diamond Shoe Metal Grinding Disc for Coating.

Conclusion

All the admixtures of DSP with 5-Durable Aluminum Flag Pole with Dome Top Tangle Free Finial-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Hospital Used pH-1200-PP Fume Hood(DSP) with 5-HT3receptor antagonists (5-Car Door Panel Molding Parts Check Fixture) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-80 Gallon Vertical 200 Psi Air Compressor Tanks.

  • What this study adds?

  • Conical Sjz 51/105 Plastic PVC/UPVC Electricity Conduit Pipe/Tube/Hose  Extrusion/Extruder Making Machinery-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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