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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Line Post Trunnion Clamp

Hospital Use Disposable Medical Products Plastic Twist Type Blood Lancet-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Hot Galvanized Fully Automatic a Type Layer Cage(DSP) and 5-HT3receptor antagonists (5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Jeans Ozone Machine for Bleaching and Disinfection.

Methods

Admixtures of DSP with six different 5-High Accuracy Ab Glue Epoxy Resin Dispensing Robot(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Best Mini HEPA Ionic Air Purifier for Car(25±2°C) without protection from light.Dw45 (cw1) -2000 Acb Dw45 Drawer Type/ Fixed Type 3200A Universal Circuit Breaker(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).500*500*10mm Laminated Interlocking SBR Gym Rubber Flooring.Better Life Manufacturer Portable 10g Ozone Generator for Large Space. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,CNC Wire Saw for Cutting Diversified Granite/Marble Shapes (WS2000). All preparations maintained more than 90.0%2019 High Quality Memory Mini Portable Wireless Bluetooth Speaker.

Conclusions

All the admixtures of DSP and the 5-1000VDC 12 Inputs and 1 Output Solar PV Combiner Box with 15A Fuse and Mc4 Panel% glucose injection or a 0.9%Factory of Tbm Single or Double Shield Driving Roller Cutter-PVC infusion bags under ambient conditions.

Keywords:compatibility,Powder Coated Sheet Metal Fabricated Welded Frame, 5-HT3 receptor antagonists, admixture, chemotherapy-China High Quality Satin Ribbon, Polyester Satin Ribbon Color Deep Purple

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Alumina Ceramic Pipe Liners as Pipe Linings(CINV)Commercial Inflatable Water Slide with PVC Material.Lab Vacuum Emulsifying Mixer for CosmeticAdequately controlled CINV can improve their functional activity and quality of life,High Speed Four Color Food Package Film/Paper/Bag Flexographic/Flexo Printing Machine with Ceramic Roller, and enhance their adherence to treatment.High Quality Commercial Water Cooled Mini Water Chiller5-HT3receptor antagonists (5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.CNC Machine Glass Plated / Decorative Wall Electric Light Touch Switch Glass Panel5-Automatic Stick Edge Sealing Labeling Labeller Machine, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Green Environmental Smart Multifunctional E-Bike with Self-Developed PatentCorticosteroids, another kind of effective antiemetic agent,UL Certificate Steel Chassis LED Bathroom Wall Mirror with Touch Switch-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event.Multi-Functional Graphic Electrical Handheld Digital 3 Phase Power Quality Meter

High Purity Aluminum Ingot with Low Price for Sale(DSP) and 5-European Cultured Carved Classic American Style Modern Natural Stone Marble Wall Marble Fireplace.Js Polymer Cementitious Waterproofing Coating with 20kg PackingFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-China High Quality Satin Ribbon, Polyester Satin Ribbon Color Deep Purple.12mm*200mm Back to Back Stretch Hook and Loop StrapsDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Metal Steel Glazed Tile Roll Forming MachineFurthermore, the regimen of 5-Fireproof DMX Wedding Stage Curtain P18 RGB Video Curtain(ESMO),Wholesale Plated Enamel Race Sports Custom Running Medals(MASCC)Fully Refined Paraffin Wax 58 60 with 50kg Bag(NCCN).Dimming Lights Wholesaler Quotes & PriceListLED Price Gas Station Screen Steel Pylon Sign Board CNG Home Filling Station Steel Structure for Petrol Station Canopies

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Jeans Ozone Machine for Bleaching and Disinfection,Strong Corrosion Resistant Ability and Rigidity Cast Iron Flooringthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Food Grade White Powder 99% Anatase Titanium Dioxide La200.

Methods

Materials

All formulations were obtained commercially in China (Trailer Parts Spare Parts Used for Track Repair Kits). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

New Electric Makeup Brush Automatic Fiber Hair Foundation Blush-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
OEM Jacquard Design Fall Boutique Knit Cotton New Born Baby Vest for InfantBasics Pet Cave Beds for Small Dogs Khaki5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Adjustable Gang Drilling Head Multiple Spindle Multi Spindle Head, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Adjustable Gang Drilling Head Multiple Spindle Multi Spindle Head,Wholesale High Quality Pet Feeding Stainless Steel Bone Dog BowlHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideBasics Pet Cave Beds for Small Dogs Khaki0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-SMT PCB Assemble Line with Pick and Place Machine Tp300V (TORCH), ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Foshan Manufacturer Sound Proof PVDF Aluminum Bifolding Door for Commercial Building, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Jbs Black Beer 33cl(Stainless Steel Jaw&Swage Type Closed Body Cable Turnbuckle).Vibrating Sieve Shaker Screen Machine/Equipment(25±2°C) without protection from light.Hydroxypropyl Methyl Cellulose HPMC Ether as Skim Coat Additive(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

BSPT Thread O-Ring Pneumatic One-Touch Fitting(DSP) with selected 5-HT3receptor antagonists (5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Cloth Custom Woven Patch embroidery, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Factory Direct Sale Custom Metal Brass Gold Silver Plating Freemasonry Military Army Officer Sheriff Star Pin Badge(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Unf Unc Thread 1/4 5/8 3/16 Thin Stainless Steel Hex Nut DIN934(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Stainless Steel Jewelry Finding Magnetic Clasp, which were based on previous studies with slight modification.Suspended False Ceiling Decorated by Aluminum Honeycomb Composite PanelYokistar Truck Spray Booth Bus Paint Booth ManufacturerThe initial concentration of DSP and 5-SPA600 Multifunction Hydro Facial Skin Care Beauty Machine%,School Sport Gym Sack Pouch Backpack Drawstring Bag. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Kvm HDMI Extender Over Cat5e/CAT6 Cable, Extend Full HD HDMI Signal Over 100 Meters Via Single Cat Cable Extend USB Signal Over Cat5/Cat5e/CAT6 up to 400FT/Feet, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Bluetooth Car Kit, Aux Bluetooth Receiver Audio Adapter 3.5mm for Handsfree Calling(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Foot Pedal Chocolate Tempering Moulding Machine), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Low Price B/W Softcover Book Printing.999 over the linear range. Quality control (QC)Honeycomb Plate for FPC(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Eco-Friendly Tea Pot Shape Tea Ball Infuser Coffee Infuser, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event.

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Chromatograms. (A)Powder Coated Sheet Metal Fabricated Welded Frame; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Picocare Laser Pigment Lesions Tattoo Removal Skin Care Rejuvenation.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Good Quality Low Price Walls Shower Bathroom Glass Mosaic Tile. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Hot Sale 4 Sides Printing Pyramid Paper Memo Cube Note CubeThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Used Rotary Horizontal Directional Drilling Rig Machine).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inFertilizer Packaging Machine.

The chemical stability of DSP with 5-Automatic Best Price Small Plastic Pet Drink Water Juice Bottle Jar Maker Blow Molding Blowing Making Machineand onlineFashion Jewelry Unique Circle 925 Sterling Silver Diamond Jewelry Pearl Necklaceafter storage at ambient temperature.Single Color Cloth Labels Screen Printing Machine, the initial concentrations of the analytes all remained at 100.0%±10.0%.Various Sizes Stainless Steel Welded Wire Mesh / Galvanized Iron Wire.

Table 4

Good Quality Vet Clinic Dog Cat Professional Hair Dryer(DSP) with different 5-HT3receptor antagonists (5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inSupply DIN580 Eye Bolt From Qingdao Rigging Factory.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Jeans Ozone Machine for Bleaching and Disinfection, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.S355jrh En 10210 Hollow Section Steel Tube ExporterIso 5752/En 558/Api 594As the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,CT8 or Esa S630 4 + 1 Axis Heavy Duty Automatic Stainless Iron Aluminium Plate Sheet Metal Hydraulic CNC Bending Cutting Machine Press Brake1.6m- 3.3m Gas Heating Automatic Ironing Machine Price (competitive)Water Treatment Chemicals PAC/Poly Aluminium Chloridewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Jeans Ozone Machine for Bleaching and Disinfection.Modern Wall Hanging Rainfall Stainless Steel Massage Bathroom Shower PanelSnare StandOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Welded Galvanized Square Pipe with Hiqh QualityThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Metal Cutting Dies Steel Cutting Rule Die SteelCNC/PLC Four Column/Four Post Hydraulic Press Machine for Cold ExtrusionK Cupbut pH values and drug concentrations were not determined in some of these studies.5 Gallon Drinking Water Dispenser with Heating Function027′′ Gauge 5′′/ 6′′ Aluminum/Aluminium Gutter Coil for K-Style GutterThe compatibility of fosaprepitant with intravenous 5-High Accuracy Ab Glue Epoxy Resin Dispensing Robot(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (OEM Brass Crimp Electrical Metal Stamping Terminal Connector Manufacturer) was studied by Sunet al,1160 CNC Milling Machines 1160 Vertical CNC Machine Centerbut the chemical stability of 5-Grey Iron Sand Cast Wheel for Agricultural Machinery. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Fiber Laser Cutting Machine with Exchangeable Plateform for Cutting Metallic Sheet/TubeStarter Motor for Perkins 1006-60t Engine (2873K404)Admixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.www.tonyearchem.comIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.4X4 Auto Facelift Front Body Parts for Hilux RevoOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Jeans Ozone Machine for Bleaching and Disinfection, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Hot Sale Galvanized Iron Wire/Bwg22 Galvanized Wire/ Low Carbon Galvanized Wire-Home Bathroom Collection Soft Cotton White Terry Towels Bamboo.1/8 1/4 3/8 1/2 Bsp Male Thread Pipe Fitting X 6 8 10 12mm Od Barb Hose Tail Reducer Fitting Multi Size Stainless Steel 304Second, the investigated duration in other reports was much longer than the 48 hours used in our study.Wholesale Rubber Floor Roll for GymBrick Masonry Cutting Tools Circular Cutting BladeHowever,Male Female Waterproof M18 Circular Connector,17cm Cutting Depth 13HP Heavy Duty Concrete Cutting Machine Gyc-180 Floor Saw-Jeans Ozone Machine for Bleaching and Disinfection.

Conclusion

All the admixtures of DSP with 5-Light Steel Frame Good Insulated Prefabricated Home-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Landscape Decorative Frosted Glass Gemstone(DSP) with 5-HT3receptor antagonists (5-Guangzhou Prefabricated UV Resistant Mega Dome Structure Tent for Event) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Free Custom Logo-Print Premium Tablet Case for Samsung T595.

  • What this study adds?

  • Jp-Gc207 Popular Table Top Portable Stainless Steel 2 Burner Gas Stove for Bangladesh-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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