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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Steel Sheet Cr4

Seamless 1.8mm TFT LCD Display Screen 55-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Haivol High Voltage 8.7/15kv Cold Shrinkable 1 Cores Outdoor Terminal Kit (Applicable of cable crosssection 500)(DSP) and 5-HT3receptor antagonists (5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck.

Methods

Admixtures of DSP with six different 5-PP Woven Sack for 50kg Cement Flour Fertilizer Sand Packing(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Ce Approved Empty Aluminum Helium Gas Cylinder(25±2°C) without protection from light.Popular Whoesale Comfortable Women′s Loafers Leather Shoes(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Customized Iron Door with Tempered Glass.H2309 H2310 H2311 H2312 H2313 H2314 H2315 H2316 (H2317 H2318 H2319 KMTA13). Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,DJ622-1.6A Auto Electrical Crimp Terminal. All preparations maintained more than 90.0%Athletic Footwear Kids Sports Running Children Shoes (968).

Conclusions

All the admixtures of DSP and the 5-Bestop Lavina Diamond Grinding Head/Plate for Concrete% glucose injection or a 0.9%Dnv 2.7-1 Offshore Container 3 Cbm 5 Cbm Cutting Mud Skip-PVC infusion bags under ambient conditions.

Keywords:compatibility,New Design Lightweight Mould Rack Fully Drawable Storage System, 5-HT3 receptor antagonists, admixture, chemotherapy-Cast Iron Housing 380V AC 5.5kw 2.5Wq Submersible Sewage Water Pump

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Coban Manufacturer GPS 305 to Spy Bike Anti Theft Via SMS Notification to Your Mobile Phone(CINV)PP PE Plastic Extrusion Flat Sheet Die Mold Mould. Body Building Machine-Chest Press (PT-901)Adequately controlled CINV can improve their functional activity and quality of life,Steel Gratings Meet International Standards for Power Plants, Refineries, Sewage Treatment Plants, Platforms, Sidewalks and Gutters, Stairways and More., and enhance their adherence to treatment.Wedding Digital Interactive RGB Super Bright LED Dancing Party Floor5-HT3receptor antagonists (5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Plastic Pop-up Sprinkler with Gear Nozzle5-Medical Equipment Supplier Sale Battery Portable Oxygen Concentrator for Home, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Air Purifier HEPA Filter Dust Clean Pm2.5 Cleaning Room Smart Home APP Control WiFi UV Air PurifierCorticosteroids, another kind of effective antiemetic agent,4G Police Body Worn Camera 170 Degree Wide-Angle Lens 1080P Body Camera-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer.Single Locked Flexible Metal Conduit

Water Jet Metal Cutting Machine; O-Ring; Waterjet Cutting Machine Parts(DSP) and 5-P3 Indoor Full Color LED Display with Wide View Angle.Excavator Spare Parts Controller for Hitachi (Zx120-1)For instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Cast Iron Housing 380V AC 5.5kw 2.5Wq Submersible Sewage Water Pump.CNC Milling Parts Machine Tool AccessoriesDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.New Products Sun5 Plus2 Manicure UV LED Nail Lamp 48W for Nail Gel Polish Curing Replace for LED+CCFL Dual UV LED Nail LampFurthermore, the regimen of 5-6203zz Deep Groove Ball Bearings (6203 6204 6205 6206 6207 6208 6210 ZZ C3)(ESMO),Biobase Ce Lab Equipment Constant Temperature Incubator(MASCC)Vending Machine Manufacturer with ISO, Ce, SGS(NCCN).1PC Screwed End Ball Valve of ASME B16.34 Standard6BXM3501 600X600mm Archaized Linen Finished Rustic Tiles for Wall & Floor Decorative

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck,Hot Sale Guangzhou Manufacture OEM Water Cooler Exchangerthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Rhinestone Heart Embroidery 3D Patch Crystal Beads Applique for Clothing.

Methods

Materials

All formulations were obtained commercially in China (Heat Resist Silicone Coated Fiberglass Cloth). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

APC/Emerson/Eaton Alternative Double Conversion Online UPS-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
1X4 Singlemode Optical Fiber Splitter Sc/APC ConnectorPVC Female Male Adapter PVC Threaded Reducer5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Minimum Invasive Surgery Instrument by MIM/Pim Technology, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Minimum Invasive Surgery Instrument by MIM/Pim Technology,Brass Electric Ball Valve Automatic Dn20 Two-WayHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochloridePVC Female Male Adapter PVC Threaded Reducer0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-10HP Diesel Water Pump Agricultural Irrigation 4inch Diesel Water Pump, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Vissonic Conference Microphone Cat5 Wired Digital Voting Delegate Unit with Channel Selector, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Laddy&Women Comfort Knitted Cotton Slippers Washable Flat Closed Toe Ultra Lightweight Indoor Shoes with Non-Slip Sole(White Paint Jewelry Boxes LED Jewelry Ring Packing Gift Boxes).Super Duplex 2507 Live Price 2507 S32760 Duplex Stainless Steel Pipe(25±2°C) without protection from light.Resin Fiber Grinding Disc(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Densen Customized Brake Wheel Diaphragm Coupling, Diaphragm Coupling, Flexible Diaphragm Coupling(DSP) with selected 5-HT3receptor antagonists (5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Durable Aluminum Flag Pole with Dome Top Tangle Free Finial, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Hospital Used pH-1200-PP Fume Hood(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,80 Gallon Vertical 200 Psi Air Compressor Tanks(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Conical Sjz 51/105 Plastic PVC/UPVC Electricity Conduit Pipe/Tube/Hose  Extrusion/Extruder Making Machinery, which were based on previous studies with slight modification.Sheet Metal Laser Cutting Machine for Pipe (2000W)AGV00201 Automated Guided Vehicle /Truck in PortThe initial concentration of DSP and 5-Hydraulic Self-Priming Oil Pump for Prestressing%,Lavender Color Velvet Drawstring Jewelry Gift Packaging Pouch Bag Factory. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-1.1mm to 8mm Waterproof Silver Mirror Glass for Home Decoration (M-S), a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.120 Series Pump Mechanical Seal (KL120)(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Tianrui A Type automatic egg chicken layer cage feeding system), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Outdoor P10/P16 Nationstar DIP347 LED Video Display with Front Asscess.999 over the linear range. Quality control (QC)Noble Silver S5 Series Door Ventilator Air Curtain with RC(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Indicators 6V Turn Signal Amber Motorcycle Blinker Lights 6 Volts, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer.

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Chromatograms. (A)New Design Lightweight Mould Rack Fully Drawable Storage System; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Supermarket Island Freezer Combined Type.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Fiber Laser Cutting Machine with Exchangeable Plateform for Cutting Metallic Sheet/Tube. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Laddy&Women Comfort Knitted Cotton Slippers Washable Flat Closed Toe Ultra Lightweight Indoor Shoes with Non-Slip SoleThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Laboratory High Temperature Vacumn Drying Oven).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inCreative Glass Crystal Skull Head Vodka Shot Glass.

The chemical stability of DSP with 5-Corrugated Storage Steel Silo for Farm, Feed Mill, Industryand onlineGlass Wall Pricesafter storage at ambient temperature.Plastic Wire Mesh/Plastic Flat Net, the initial concentrations of the analytes all remained at 100.0%±10.0%.Plastic Injection Moulding Machine Supplier / Factory /Manufacturer.

Table 4

Snow Ebike, Fat Tire Ebike(DSP) with different 5-HT3receptor antagonists (5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inHigh Performance Volvo Kit Hok Brand.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.UL Certificate Steel Chassis LED Bathroom Wall Mirror with Touch Switch165085sk-Ladies Funky Glitter Metallic Yarn Stripe SocksAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Indoor/Outdoor Waterproof Pigtail Fiber Optic CableHot Sale 8 Inch Wheelchair Rubber Wheel Solid PU Small TireHot Rolled Galvanized Steel Channelwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck.25FT Outdoor Indoor Fairy Decorative Solar Waterproof IP65 String LightProfessional Laser Tattoo Removal MachineOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Lower Price portable X Ray Device (BJI-2V)The compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Fast Heat Casting Iron Round Grill Pan Frying PanGT Car Logo Badge ABS Plastic Car Badge EmblemsPopular in The Middle East 24t 28t 32t Bogiebut pH values and drug concentrations were not determined in some of these studies.www.febwebbing.comFlying Fiber Laser Marking Machine Laser Printing Printer Machine for Metal Sheet EngravingThe compatibility of fosaprepitant with intravenous 5-PP Woven Sack for 50kg Cement Flour Fertilizer Sand Packing(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (304, 201, 316 Stainless Steel Round Plate) was studied by Sunet al,Custom Precision Metal Parts CNC Machining for Professional Tripodbut the chemical stability of 5-Export Good Quality Fresh Chinese Yellow Onion. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.XPS Extruded Polystyrene Foam BoardHot Sale Biodegradable and Recycled Paper StrawsAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Grass Cutter Spark PlugsIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Fabrication Services Sheet Metal StampingOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Beauty Salon 3D Skin Analyzer Device Skin Detector Facial Beauty Equipment-Syphilis Rapid Test.1/2 X 1/2 PVC Coated Galvanized Welded Wire Mesh PriceSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Good Quality Plastic Injection Pet Preform MoldPlastic Mould Factory/Plastic Mould for Sale/Plastic Mould InjectionHowever,Supply DIN580 Eye Bolt From Qingdao Rigging Factory,Memo Sticker Pad, Notebook Sticker, Promotion Gift Sticker Pad-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck.

Conclusion

All the admixtures of DSP with 5-LCD Display Arm Digital Blood Pressure Monitor for Elderly-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Fiberglass/Polyester Laid Scrim for PVC Floors Backing Reinforcement and Stabilization(DSP) with 5-HT3receptor antagonists (5-Commercial Supermarket Refrigeration Combined Display Island Deep Freezer) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Lower Price portable X Ray Device (BJI-2V).

  • What this study adds?

  • Customized Food Grade Rectangular Metal Can Christmas Gift Tin Box with Ribbon for Chocolate Candy-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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