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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:Gouging Carbon Rod

Cutting Hard Alloy Kentanium Disc Abrasive Disc for Quartz Stone-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.High Quality Metal Roofing Fasteners/Self Drilling Screw(DSP) and 5-HT3receptor antagonists (5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip.

Methods

Admixtures of DSP with six different 5-Quartz Silica Polished Fused Quartz Plate High Quality Quartz Disc(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Full Color Outdoor/Indoor Rental LED Screen Panel/LED Sign/LED Display P5.95 P4.81 P3.91 for LED TV Video Wall Billboard Modules 500*500/500*1000 mm Cabinet(25±2°C) without protection from light.Home Use Portable Slimming Beauty Device Ultrasonic Facial Massager(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Stainless Steel Aluminum Bending Sheet Metal Fabrication Welding Parts.Stainless Steel Pipe Manufacturers. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,CNC Machine Parts Aluminum and ABS Mock up Prototypes. All preparations maintained more than 90.0%Semi-Automatic Charcoal Bagging Machine.

Conclusions

All the admixtures of DSP and the 5-2017 Internal Screwed Tungsten Carbide Boring Bar with Cooling Hole% glucose injection or a 0.9%Efficient Powder Coating Line with Manual Spray Booth-PVC infusion bags under ambient conditions.

Keywords:compatibility,High Strength Cr12MOV Stainless Steel Plate&Sheet for Thread Rolling Die, 5-HT3 receptor antagonists, admixture, chemotherapy-High Quality Fully Automatic Aluminium Foil Container Production Line Ce ISO Certified

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Permanent Magnets Neodymium for Fishing Tools 20*10*2mm(CINV)Factory Price and High Quality R32 45mm Rock Drill Button Bits for Mining Quarrying Tunneling.Tire Tyre Curing Press with ISO BV SGSAdequately controlled CINV can improve their functional activity and quality of life,XPE Camping Mat Crawling Folding Mat Baby Play Mat, and enhance their adherence to treatment.JIS G3466 Stkr490 Square Steel Tube5-HT3receptor antagonists (5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Shantui Dozer Transmission Piston Seat 175-15-41189 175-15-428605-Used Rotary Horizontal Directional Drilling Rig Machine, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Yuchai Yc6K6000b-N Engine Parts PistonCorticosteroids, another kind of effective antiemetic agent,Higo Factory Price Metal Eyeglasses with Clip on Magnetic Sunglasses for Driving-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy.Explosion-Proof Hydraulic Crawler Excavator with Quick Coupling

Rebar Steel Threading Wire Rod Rolling Machine on Sale(DSP) and 5-New Product 125kHz Em&Tk4100 RFID Card/RFID Smart Card.Scaffolding Fence Fire Retardant Debris NettingFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-High Quality Fully Automatic Aluminium Foil Container Production Line Ce ISO Certified.3kw Power Tool 1200mm Diamond Concrete Cutting Wall Saw MachineDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Fiber Optic Cleaning Cassette Replacement ReelFurthermore, the regimen of 5-Visbella DIY Sew Adhesive Stickers for Fabric(ESMO),Mining Diesel Engine Driven Portable Movable Screw Air Compressor for Construction Industry 140-1687 Cfm(MASCC)Square Milky PC LED Light Housing with Linear Polycarbonate Linear Diffuser(NCCN).Process Cooling ChillerPalm Aneroid Sphygmomanometer with Ce and ISO

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip,JIS Standard Wafer Type Butterfly Valvethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Nellcor non-oximax 7pin infant disposable sensor, cream.

Methods

Materials

All formulations were obtained commercially in China (Pyramid Shaped Paper Memo Note Cube as Gift). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

2020f-5 Die Casting Aluminium and Zinc Connector of Custom Bracket for 20 Series Industrial Extrusion-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
3 Colors Labels Ribbons Automatic Screen Printing MachineMedical Ysx1525 Customized 2mmpb X-ray Protection Lead Door5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Genuine Piston for Komastu Engine 6D102, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Genuine Piston for Komastu Engine 6D102,Large Capacity Cell Cabinet Lockers for Vending Machine with Auto Opened DoorHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideMedical Ysx1525 Customized 2mmpb X-ray Protection Lead Door0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Sicher Elevator Hospital Bed Elevator, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Climatic Cycling Stability Testing Chamber Temperature Humidity Cabinet, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Stainless Steel A2 Metric Extra Fine Thread Thin Jam Hex Nuts DIN 439b M2, M3, M4, M5, M6, M8, M10, M12(Diamond Tools Continous Saw Blade Segment Bldes Turbo Saw Blades Brazed Welded Saw Blades).Disposable Medical Ventilator Breathing Circuit Anesthesia Smoothbore Corrugated Watertraps(25±2°C) without protection from light.Ready to Ship CAT5E UTP RJ45 8P8C Short Body Modular Plug(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Sinotruk HOWO Truck Spare Parts Cooling Water Outlet Pipe (Wg9719530227)(DSP) with selected 5-HT3receptor antagonists (5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Printing Number Women Sports and Fitness Wear, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Customized Export Standard Galvanized Triangle Roller Carrier Manufacturer/Frame/Steel Bracket(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Small Stainless Steel Food Grade Juice Circulating Transfer Pump(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Detachable 8 in 1 Sandwich Toaster Waffle Maker Grill with Timer, which were based on previous studies with slight modification.Heavy Duty Foldable Plastic Pallet ContainerWashing Glove Nonwoven Wipes Making MachineThe initial concentration of DSP and 5-Modern Metal Leather Dining Chair for Restaurant Cafe Furniture%,30W/50W/100W/150W/200W IP65 Outdoor Rechargeable Handle LED Flood Light Factory. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Popular Wooden Grain Design Furniture Plywood, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Ocrown Unicorn Chrome Mirror Aurora Pearlscent Mermaid Powder Rainbow Pigments(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (New Product 3V DC 0716 Small Vibrating Motors for Massager), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Warm Polyester Quilt in White Color (DPF201519).999 over the linear range. Quality control (QC)Gw501516 Powder Have Incredible Endurance Benefits CAS: 317318-70-0(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Ce Certification All Terrain Track Mini Dumper, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy.

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Chromatograms. (A)High Strength Cr12MOV Stainless Steel Plate&Sheet for Thread Rolling Die; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.PV Union L Quick Connect Pneumatic Fittings.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Economical Supermarket Freezer for Ice Cream, Commercial Chest Freezer. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.HPL HDF Matte White Melamine Laminated Chipboard MDF BoardThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Fireproof DMX Wedding Stage Curtain P18 RGB Video Curtain).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inOutdoor LED Spot Stage Light Wall Washer.

The chemical stability of DSP with 5-125kHz-13.56 MHz NFC RFID Wet Inlayand onlineCustom High Precision Plastic Injection Molding Small Partsafter storage at ambient temperature.1500cc 4X4 Beach Buggy Renli Ourtdoor Sports Go Kart for Sales (MC-456), the initial concentrations of the analytes all remained at 100.0%±10.0%.Alumina Ceramic Square Tile Mat as Wear Lining.

Table 4

Cat Cave Premium Felt Cat Nest Cat House with Removable Cushion(DSP) with different 5-HT3receptor antagonists (5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.4 Bearing Ball Heavy Duty Stainless Steel Door Hinge for TruckPedestal Sump PumpAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,2020f-5 Die Casting Aluminium and Zinc Connector of Custom Bracket for 20 Series Industrial ExtrusionBottle Cap Liner Making Machine/PE Foam Sheet Extrusion MachineFC Upc APC Single Mode Multi-Mode Simplex Fiber Optic Couplerwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip.PP Sediment Water Filter Cartridge for RO SystemCo2 Laser Tube Refill 100wOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Powful Painting Machine for PuttyThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,HPMC for Construction Industry/ Wall Coating /Putty PowderMetal Lathe CZ1324G Precision Mini Lathe Cheap Ben Lathe CZ1324GOutdoor Spaces and Pool House Interiors Innovative Design in Classical Rattan Woven Modular Armless Lounge Sofa Centre Unitbut pH values and drug concentrations were not determined in some of these studies.Custom Made High Pressure Cold Forging Blind FlangeDie Casting Precision Customized Mini LED Aluminum RadiatorThe compatibility of fosaprepitant with intravenous 5-Quartz Silica Polished Fused Quartz Plate High Quality Quartz Disc(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Fashion Custom Deisgn Pod Running Wholesale Shoes Slip on Sneakers for Women Comfortable Canvas Running Shoes Novelty Sloth Gifts with Logos) was studied by Sunet al,Factory Price Customize BOPP Packing Tapebut the chemical stability of 5-Aluminum Pneumatic Actuator Clamp Butterfly Valve with Single Bracket. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Stainless Steel Closed Body Turnbuckle AluminumAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.IR Tunnel Dryer for Non-Woven WipesIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication CableOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Twin Blade Disposable Razor Disposable Shaving Safety Razor-Energy Saving Brazed Plate Heat Exchanger, Air Heat Exchanger.40tons High Speed EVA Die Cutting Machine (HG-A40T)Second, the investigated duration in other reports was much longer than the 48 hours used in our study.Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456Disposable Medical Blood Collection Needle Lancet Pen TypeHowever,3D Dental Oral Scanner for Dental Clinic,High Quality Women Fitness Wear Sport Yoga Suit Sportswear-Shaft Elastic Retaining Ring Cirsnap Ring Elastic Collarclip.

Conclusion

All the admixtures of DSP with 5-Concrete Nail Making Machine Production Line/Coil Nail Making Machine and Nail Thread Rolling Machine/Nail Twisting Machine-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Star Shaped LED Lights String Curtain Window Bedroom Xmas Fairy Lamp Home Deco(DSP) with 5-HT3receptor antagonists (5-Patio Furniture Chaise Lounger Chair Swing Hammock Chair with Canopy) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-China Manufacturer Supply Roll Pass Shot Blast Cleaning Machine for Steel Plate.

  • What this study adds?

  • Hot Sale Children Pop-up Book Printing, 3D Children Board Book, Hard Cover Children Pop-up Book-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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