Steyr 150HP Boat Motor Weichai Inboard Marine Diesel Engine Price-HT3receptor antagonists in infusion solutions: a comprehensive study
Guangzhao He
1Department of Pharmacy,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
2Department of Pharmacy, Changzhou Tumor Hospital, Changzhou, Jiangsu, China
Fan Zeng
3Nursing Department,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Kai Lei
1Department of Pharmacy,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Shu Xia
4Department of Oncology,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Li Deng
1Department of Pharmacy,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Chengliang Zhang
1Department of Pharmacy,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Dong Liu
1Department of Pharmacy,Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, Huazhong University of Science and Technology, Wuhan, Hubei, China
Associated Data
Abstract
Objectives
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.China Aluminum Alloy Wire Mesh/Aluminum Insect Screen/Aluminum Mosquito Net for Sale(DSP) and 5-HT3receptor antagonists (5-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Portable Type Inductor.
Methods
Admixtures of DSP with six different 5-Construction Equipment Robin Engine Water Pumps Price(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Fiberglass Fiber Glass Cloth, Tape, Vermiculite, Titanium Rope Cloth, Glass Fiber Rope(25±2°C) without protection from light.Outdoor LCD Display Touch Screen Kiosk for Advertising(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).1580551---89023368--Cooling-Fan-Motor--for-Chevrolet-Silverado-Suburban-Gmc-Sierra.Sulfur Recovery Catalyst in Oil Refinery Industry with Lowest Price. Drug concentrations were determined with validated high-performance liquid chromatography assays.
Results
No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,CNC Milling Parts Machine Tool Accessories. All preparations maintained more than 90.0%Ysb-U3V Full Digital Mechanical Sector Ultrasonic Diagnostic Instrument.
Conclusions
All the admixtures of DSP and the 5-4 Ports Powerful 30W Pd Charger for MacBook and Laptop% glucose injection or a 0.9%Plastic Exterior Wall Decorative Panel-PVC infusion bags under ambient conditions.
EAHP Statement 4: Clinical Pharmacy Services.
Introduction
Chemotherapy-Bonfiglioli Ta Series Helical Gearing Arrangement Gearbox(CINV)Laser Infrared Active Detector Sensor Infrared Beam Detector Active Infrared 4 Beam Detector.Outdoor Portable Travel Automatic Water Feeder for Pet&Dog&CatAdequately controlled CINV can improve their functional activity and quality of life,Cheap UV Shading Net, Privacy Pool Shade Cover Coating Film Shade Sails, and enhance their adherence to treatment.High Strength Continuous Filament Polyester Nonwoven Geotextile for Construction5-HT3receptor antagonists (5-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Climatic Cycling Stability Testing Chamber Temperature Humidity Cabinet5-Professional Cosmetic Makeup Box with 4 Trays (HB-2203), Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Best Price Lvl PlankCorticosteroids, another kind of effective antiemetic agent,Aluminium Profile/Shell/Housing for T5/T8 LED Tube Light (SQ-H0077)-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack.Male Female Waterproof M18 Circular Connector
Professional Wood Processor Log Splitter for Skid Steer(DSP) and 5-Hot Sale Magnetic Strip Inserting Making Machine.Longyi Crimping Types Cable Terminal LugsFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Customized Size Outdoor P6 Full Color Front Service Advertising LED Display Sign.Tianjin Manufacturer Supply Good Price Aluminum Capillary Tube/PipeDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Stainless Steel Pipe ManufacturersFurthermore, the regimen of 5-Wedding Digital Interactive RGB Super Bright LED Dancing Party Floor(ESMO),High Defination Round HDMI Cable for 2.0V 4K*2K 1080P (008PC)(MASCC)Fluorescent Tape Black Arrow Reflective Guiding Tape Safety(NCCN).yishanjiushe.comCockroach House Cockroach Glue Trap
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Portable Type Inductor,Visbella DIY Sew Adhesive Stickers for Fabricthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-S3 Anchor for Post Tensioning.
Methods
Materials
All formulations were obtained commercially in China (4mm 6mm Limestone Honeycomb Aluminum Composite Panel for Indoor/Outdoor Wall Cladding). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.
Table 1
Drug | Formulation | Specification | Excipient | Manufacturer | Lot number |
---|---|---|---|---|---|
Anon Sesame Cutter Mini Manual Harvester for Rice Wheat Bean | Black Steel Square Pipe, Bright Surface for Furniture, Rectangular Black Pipe | 5 mg | Mannitol, water for injection | BBCA Pharmaceutical Co (Anhui, China) | 150130-1 |
Ondansetron hydrochloride | Injection | 8 mg/4 mL | Citric acid,B0401 Cheap EMS System Electro Stimulation Slimming Machine for Sale, NaCl | Ningbo Team Pharmaceutical Co (Zhejiang, China) | 140294A02 |
Tropisetron hydrochloride | Infusion | 5 mg/100 mL | NaCl, HCl | Qilu Pharmaceutical Co (Shangdong, China) | 3C14111803 |
Dolasetron mesylate | Injection | 12.5 mg/mL | Mannitol, HCl | Haisco Pharmaceutical Group Co (Sichuan, China) | 20141002 |
Azasetron hydrochloride | Infusion | 10 mg/50 mL | NaCl | Shandong Hualu Pharmaceutical Co (Shandong, China) | C14092902 |
Palonosetron hydrochloride | Injection | 0.25 mg/5 mL | NaCl, citric acid,B0401 Cheap EMS System Electro Stimulation Slimming Machine for Sale,Precision Plastic Bluetooth Earphone Accessories Automotive Parts by Injection Molding | Hangzhou Jiuyuan Gene Engineering Co (Zhejiang, China) | 20150102 |
Ramosetron hydrochloride | Black Steel Square Pipe, Bright Surface for Furniture, Rectangular Black Pipe | 0.3 mg | Glucose | Cisen Pharmaceutical Co (Shangdong, China) | 1410120912 |
5% Glucose | Infusion | 5 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504042 |
0.9% NaCl | Infusion | 0.9 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504103 |
Water for injection | Injection | 5 mL | None | Hubei Kelun Pharmaceutical Co (Hubei, China) | C140812E |
The 5-Plastic HDPE Pipe Extrusion Machine, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Pgz1000 Crystal Industry Pneumatic Scraper Bottom Discharge Flat Basket Filter Centrifugal Separator, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Sc Specification Electrical Tinned Copper Cable Terminal Lugs(Wooden Music Boxes).Special Design Greenhouse Steel Structure for EU Type(25±2°C) without protection from light.Stainless Steel Seamless Coiled Tubing Tube(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).
Table 2
5-HT3RA | Solvent | Nominal concentration (μg/mL) | ||
---|---|---|---|---|
Code of admixtures | DSP | 5-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack | ||
A | Ondansetron hydrochloride | 5% glucose | 100.0 | 80.0 |
B | Ondansetron hydrochloride | 5% glucose | 200.0 | 80.0 |
C | Ondansetron hydrochloride | 0.9% NaCl | 100.0 | 80.0 |
D | Ondansetron hydrochloride | 0.9% NaCl | 200.0 | 80.0 |
E | Tropisetron hydrochloride and 0.9% NaCl | None | 100.0 | 50.0 |
F | Tropisetron hydrochloride and 0.9% NaCl | None | 200.0 | 50.0 |
G | Dolasetron mesylate | 5% glucose | 100.0 | 1000.0 |
H | Dolasetron mesylate | 5% glucose | 200.0 | 1000.0 |
I | Dolasetron mesylate | 0.9% NaCl | 100.0 | 1000.0 |
J | Dolasetron mesylate | 0.9% NaCl | 200.0 | 1000.0 |
K | Azasetron hydrochloride and 0.9% NaCl | None | 100.0 | 200.0 |
L | Azasetron hydrochloride and 0.9% NaCl | None | 200.0 | 200.0 |
M | Palonosetron hydrochloride | 5% glucose | 100.0 | 2.5 |
N | Palonosetron hydrochloride | 5% glucose | 200.0 | 2.5 |
O | Palonosetron hydrochloride | 0.9% NaCl | 100.0 | 2.5 |
P | Palonosetron hydrochloride | 0.9% NaCl | 200.0 | 2.5 |
Q | Ramosetron hydrochloride | 5% glucose | 100.0 | 3.0 |
R | Ramosetron hydrochloride | 5% glucose | 200.0 | 3.0 |
S | Ramosetron hydrochloride | 0.9% NaCl | 100.0 | 3.0 |
T | Ramosetron hydrochloride | 0.9% NaCl | 200.0 | 3.0 |
Physical and chemical analysis
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HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Precision Investment Casting Engineering Machinery Parts CNC Machining, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Portable Glass Beads Waterborne Road Marking Paint(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.
The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Wholesale Profile Airport Luggage PVC Conveyor Belt Made in China), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Outdoor Portable Travel Automatic Water Feeder for Pet&Dog&Cat.999 over the linear range. Quality control (QC)Yokistar Truck Spray Booth Bus Paint Booth Manufacturer(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Hand Washing Liquid Bottle Machines, Pet Plastic Bottle Making Machine, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack.
The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Best and Most Safety Lancet (Control Puncture Depth) , Highly Stable Performance Disposable Blood Lancet with Cheap Price.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Waterproof Nylon Spinner Wheels Soft Travel Durable Trolley Luggage Bag Suitcase Ks004e. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.
Results
Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.10ml Essential Oil Perfume Bottle Automotive Perfume Pendant Bottle Glass VialThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Classic Bone Drill Medical Electric Surgical Instrument Orthopedic Drilling Power Tool).
Table 3
Admixture code* | Storage time (hours) | |
---|---|---|
0 | 48 | |
A | 4.7±0.0 | 4.6±0.0 |
B | 5.8±0.0 | 5.7±0.0 |
C | 5.3±0.0 | 5.2±0.0 |
D | 5.9±0.1 | 5.8±0.0 |
E | 6.8±0.1 | 6.6±0.1 |
F | 6.9±0.0 | 6.8±0.0 |
G | 4.8±0.0 | 4.7±0.0 |
H | 5.1±0.0 | 5.1±0.0 |
I | 5.0±0.0 | 5.0±0.0 |
J | 5.4±0.0 | 5.4±0.0 |
K | 3.9±0.0 | 3.7±0.0 |
L | 5.0±0.0 | 4.6±0.0 |
M | 5.5±0.1 | 5.5±0.0 |
N | 6.3±0.0 | 6.3±0.0 |
O | 6.1±0.0 | 6.1±0.0 |
P | 6.4±0.0 | 6.4±0.0 |
Q | 6.2±0.0 | 6.1±0.0 |
R | 6.7±0.0 | 6.6±0.0 |
S | 6.9±0.0 | 6.8±0.0 |
T | 7.1±0.0 | 7.0±0.0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted in10000W Solar Panels Power Energy Systems for Air Conditioner.
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Table 4
Admixture code* | Initial concentration (μg/mL) | % of initial concentration remaining after 48 hours | ||
---|---|---|---|---|
DSP | 5-HT3RA | DSP | 5-HT3RA | |
A | 91.8±1.0 | 74.5±0.9 | 101.2±0.1 | 101.5±0.2 |
B | 181.3±2.1 | 72.2±0.8 | 101.2±0.1 | 101.4±0.2 |
C | 92.7±1.1 | 74.5±0.9 | 101.6±0.2 | 99.9±0.1 |
D | 179.6±1.8 | 72.4±0.5 | 99.1±0.1 | 99.9±0.1 |
E | 99.1±0.4 | 50.5±0.5 | 99.2±0.1 | 99.3±0.2 |
F | 198.3±2.2 | 50.1±0.4 | 100.5±0 | 99.0±0.4 |
G | 91.4±1.2 | 924.6±8.5 | 99.6±0.8 | 99.7±1.0 |
H | 185.1±1.1 | 918.1±7.9 | 100.0±0.6 | 98.8±0.3 |
I | 91.2±0.9 | 916.6±10.1 | 99.1±0.7 | 99.0±0.5 |
J | 188.2±1.5 | 934.6±10.6 | 98.8±0.5 | 99.1±0.7 |
K | 98.9±0.5 | 198.7±2.6 | 97.5±0.5 | 99.3±0.4 |
L | 197.7±2.4 | 197.9±2.3 | 97.4±0.4 | 99.7±0.4 |
M | 90.2±2.1 | 2.3±0.1 | 98.9±0.9 | 100.1±0.3 |
N | 181.4±2.9 | 2.2±0.1 | 99.5±1.2 | 99.8±0.3 |
O | 90.8±1.3 | 2.3±0.0 | 98.7±1.2 | 99.2±1.0 |
P | 182.1±2.6 | 2.3±0.1 | 99.1±1.6 | 99.4±1.1 |
Q | 88.5±0.9 | 2.7±0.1 | 99.3±1.0 | 100.2±0 |
R | 183.1±1.5 | 2.7±0.1 | 98.3±0.9 | 99.5±0 |
S | 91.3±0.8 | 2.8±0.0 | 98.6±0.3 | 100.2±0.5 |
T | 180.2±2.4 | 2.7±0.1 | 101.6±0.3 | 100.7±0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted in M10.
Discussion
In this comprehensive study on the compatibility of DSP with six different 5-Portable Type Inductor, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.High Quality Women Fitness Wear Sport Yoga Suit Sportswear3tier Metal Table Top Wine Holder Stand Rack for Home Bar CabinetAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Unf Unc Thread 1/4 5/8 3/16 Thin Stainless Steel Hex Nut DIN93455kw 65kw Industrial Air Cooled Water Chiller UnitTune Manufacturer for Mango Fruit Washing Waxing and Grading Machinewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Portable Type Inductor.Customized Printing Beverage Juice Liquid Food Packaging Bag with SpoutNapkin Holder For RestaurantsOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Summer Womens T-Shirt Plus V-Neck Flower Printed Blouse TshirtThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,9 Inch Fabric Ice Pack for Hot and Cold Therapy10 Inch UL FM Sch10 Fire Fighting Steel PipesWholesale Plated Enamel Race Sports Custom Running Medalsbut pH values and drug concentrations were not determined in some of these studies.Laboratory Microscope Polarised Light Microscopy for Hot SaleStainless Steel Perforated Sheets Made in ChinaThe compatibility of fosaprepitant with intravenous 5-Construction Equipment Robin Engine Water Pumps Price(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Medical Ce Approved Fast Hair Removal IPL Shr Beauty Machine for Sale (HS-310)) was studied by Sunet al, Organic Fertilizerbut the chemical stability of 5-Galvanized Platform Steel Bar Grating for Floor. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.
Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Shs/Rhs Ss400 En10219 ASTM A500 Gr-a or BPortable RF Bio Light SPA Deep Cleansing Facial Oxygen Water Dermabrasion MachineAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.100ml Bottle Black Suppliers for SaleIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Good Quality Wall-Mounted Ozone Generator with 10g/H OzoneOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.
Although our study supports the compatibility and stability of DSP with 5-Portable Type Inductor, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Fr4 Camera PCB Fr4 Double Layer PCB-Double Pawls 1 Ton Chain Block Good Price India.Low Frequency Converter 0.75kw-2.2kw 1 Phase Input 3 Phase Output Frequency Inverter 50Hz to 60HzSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.IP44 Waterproof 16A 220V 3 Pin Electrical Male and Female Industrial Plug and Socket2s3p 7.4V 4500mAh 18650 Li-ion Battery PackHowever,Laptop Desktop Computer Motherboard PCB Circuit Board Assembly PCBA,Made for You Universal Wireless RF Remote Control Duplicator Yet088-Portable Type Inductor.
Conclusion
All the admixtures of DSP with 5-Rental Series P5 SMD Outdoor Full Color Display LED Screen-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.
What is already known on this subject?
Low Frequency Converter 0.75kw-2.2kw 1 Phase Input 3 Phase Output Frequency Inverter 50Hz to 60Hz(DSP) with 5-HT3receptor antagonists (5-2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack) in infusion solutions, but the available evidence is not yet conclusive.
The use of extemporaneously prepared admixtures of DSP with 5-20 Years Warranty A2 3mm ACP Sheet Price.
What this study adds?
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Footnotes
Competing interests:None declared.
Provenance and peer review:Not commissioned; externally peer reviewed.
Data sharing statement:All data from our study are included.
References
Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group