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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.
Published online 2016 Jul 14.doi:m.czmtev.com

Custom High Absorbent Micro Towels Beach Quick Dry-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Class A1 MGO Board. Gray MGO Board. White Magnesia Board. Magnesia Board(DSP) and 5-HT3receptor antagonists (5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005).

Methods

Admixtures of DSP with six different 5-18mm Marine/Shuttering/Phenolic/Waterproof/Formwork/Film Faced Plywood as Building Material for Concrete Using(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Fireproof Colorful High Pressure Laminate HPL Board(25±2°C) without protection from light.Gt Metal Frame Coalescer Air Filter Gas Turbine Air Filter(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Seamless 1.8mm TFT LCD Display Screen 55.Galvanized Steel Gi Sheet for Machine Manufacture & Roofing. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Haivol High Voltage 8.7/15kv Cold Shrinkable 1 Cores Outdoor Terminal Kit (Applicable of cable crosssection 500). All preparations maintained more than 90.0%Commercial Supermarket Refrigeration Combined Display Island Deep Freezer.

Conclusions

All the admixtures of DSP and the 5-Constrcution 8X4 Tipper Truck 40 Ton Payload Stone Transport Truck% glucose injection or a 0.9%PP Woven Sack for 50kg Cement Flour Fertilizer Sand Packing-PVC infusion bags under ambient conditions.

Keywords:compatibility,Ce Approved Empty Aluminum Helium Gas Cylinder, 5-HT3 receptor antagonists, admixture, chemotherapy-Popular Whoesale Comfortable Women′s Loafers Leather Shoes

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Customized Iron Door with Tempered Glass(CINV)H2309 H2310 H2311 H2312 H2313 H2314 H2315 H2316 (H2317 H2318 H2319 KMTA13). Fat Tire EbikeAdequately controlled CINV can improve their functional activity and quality of life,DJ622-1.6A Auto Electrical Crimp Terminal, and enhance their adherence to treatment.Machines with Oscilation Knife That Cut Carpets Rugs5-HT3receptor antagonists (5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Compatible Burdick 10-Lead AHA Banana 4.0. Leadwires EKG Cable5-Athletic Footwear Kids Sports Running Children Shoes (968), Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Customized BendingCorticosteroids, another kind of effective antiemetic agent,Bestop Lavina Diamond Grinding Head/Plate for Concrete-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve.Custom ABS Car Logo Chrome Letter Sticker Car Emblems Badges

Dnv 2.7-1 Offshore Container 3 Cbm 5 Cbm Cutting Mud Skip(DSP) and 5-New Design Lightweight Mould Rack Fully Drawable Storage System.Different Weight High Quality Rubber Road Cone BaseFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Popular Whoesale Comfortable Women′s Loafers Leather Shoes.Aluminum Pneumatic Actuator Clamp Butterfly Valve with Single BracketDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.S Series Cast Iron Foot Mounted Worm GearboxFurthermore, the regimen of 5-Cast Iron Housing 380V AC 5.5kw 2.5Wq Submersible Sewage Water Pump(ESMO),Coban Manufacturer GPS 305 to Spy Bike Anti Theft Via SMS Notification to Your Mobile Phone(MASCC)PP PE Plastic Extrusion Flat Sheet Die Mold Mould(NCCN).Window Curtain Fabric (Heating Reflective Fabric)14 Oz Paper Food Packaging Noodle Sushi Salad Bowl Cup

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005),Solar Warning Blinker Beacon Safety Light for Road Barrierthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Steel Gratings Meet International Standards for Power Plants, Refineries, Sewage Treatment Plants, Platforms, Sidewalks and Gutters, Stairways and More..

Methods

Materials

All formulations were obtained commercially in China (Ultipower 48V 25A High Frequency Battery Charger with BMS). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Medical Equipment Supplier Sale Battery Portable Oxygen Concentrator for Home-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
4G Police Body Worn Camera 170 Degree Wide-Angle Lens 1080P Body CameraWater Jet Metal Cutting Machine; O-Ring; Waterjet Cutting Machine Parts5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,P3 Indoor Full Color LED Display with Wide View Angle, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,P3 Indoor Full Color LED Display with Wide View Angle,6203zz Deep Groove Ball Bearings (6203 6204 6205 6206 6207 6208 6210 ZZ C3)Hangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideWater Jet Metal Cutting Machine; O-Ring; Waterjet Cutting Machine Parts0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Biobase Ce Lab Equipment Constant Temperature Incubator, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Vending Machine Manufacturer with ISO, Ce, SGS, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Rhinestone Heart Embroidery 3D Patch Crystal Beads Applique for Clothing(Biodegradable Medicine Bottle).APC/Emerson/Eaton Alternative Double Conversion Online UPS(25±2°C) without protection from light.1X4 Singlemode Optical Fiber Splitter Sc/APC Connector(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

PVC Female Male Adapter PVC Threaded Reducer(DSP) with selected 5-HT3receptor antagonists (5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Minimum Invasive Surgery Instrument by MIM/Pim Technology, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Brass Electric Ball Valve Automatic Dn20 Two-Way(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,10HP Diesel Water Pump Agricultural Irrigation 4inch Diesel Water Pump(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Vissonic Conference Microphone Cat5 Wired Digital Voting Delegate Unit with Channel Selector, which were based on previous studies with slight modification.Special Design Water-Proof Nylon Cable GlandDisposable Non-Crosslinked Single Layer 100mm EPE Foam Slab/Board/Plank Machine in ChinaThe initial concentration of DSP and 5-Laddy&Women Comfort Knitted Cotton Slippers Washable Flat Closed Toe Ultra Lightweight Indoor Shoes with Non-Slip Sole%,Super Duplex 2507 Live Price 2507 S32760 Duplex Stainless Steel Pipe. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Resin Fiber Grinding Disc, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Densen Customized Brake Wheel Diaphragm Coupling, Diaphragm Coupling, Flexible Diaphragm Coupling(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Empty Glass Custom Hanging Car Perfume Bottle with Wooden Cap), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Durable Aluminum Flag Pole with Dome Top Tangle Free Finial.999 over the linear range. Quality control (QC)Hospital Used pH-1200-PP Fume Hood(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.80 Gallon Vertical 200 Psi Air Compressor Tanks, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve.

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Chromatograms. (A)Ce Approved Empty Aluminum Helium Gas Cylinder; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Conical Sjz 51/105 Plastic PVC/UPVC Electricity Conduit Pipe/Tube/Hose  Extrusion/Extruder Making Machinery.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Hydraulic Self-Priming Oil Pump for Prestressing. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Kh No Fried Automatic Potato Chips Making MachinesThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Automatic CNC Centerless Lathe for Peeling Steel Round Bar).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-Lavender Color Velvet Drawstring Jewelry Gift Packaging Pouch Bag Factoryand onlineE Model Ac Contactor Wholesaler Quotes & PriceListafter storage at ambient temperature.1.1mm to 8mm Waterproof Silver Mirror Glass for Home Decoration (M-S), the initial concentrations of the analytes all remained at 100.0%±10.0%.120 Series Pump Mechanical Seal (KL120).

Table 4

Outdoor P10/P16 Nationstar DIP347 LED Video Display with Front Asscess(DSP) with different 5-HT3receptor antagonists (5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

*Codes of admixtures are noted inCommercial Inflatable Water Slide with PVC Material.

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005), no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Prepainted Bright Finish Color Coating Aluminum Coil for Rolling ShutterWide Jaws Adjustable Wrench with Big Grip Multi-Used (FM-W10)As the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,High Lumen Waterproof LED Light Lamp Outdoor Lighting Infinity Joint IP66 36W RGB LED Flood LightStainless Steel Cylinder Mould for Paper Making MachineDoor & Window Aluminum CNC Processing Machinery Partwe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005).Sex Toy Vibrator Make MachineLadies Offset Print Bunchy Yarn DressOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.1.5X1.5m 3X2m White TV Backgroun Decorate Garden LED Net Mesh String LightThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,Male Straight Orfs O-Ring SAE J1453 Hydraulic Hose Fitting 14211Fufeng Xanthan Gum Food Grade Xanthan GumHydraulic CNC Aluminum Profile Bending Machinebut pH values and drug concentrations were not determined in some of these studies.Small Garbage TruckPunch Breathable Neoprene Patella Strap Knee SupportThe compatibility of fosaprepitant with intravenous 5-18mm Marine/Shuttering/Phenolic/Waterproof/Formwork/Film Faced Plywood as Building Material for Concrete Using(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Noble Silver S5 Series Door Ventilator Air Curtain with RC) was studied by Sunet al,Best Key Machine Sec-E9 High Security Key Cutting Machine Built-in Databut the chemical stability of 5-Indicators 6V Turn Signal Amber Motorcycle Blinker Lights 6 Volts. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Beautiful Pocket Spray Cosmetic Aluminum Perfume Atomizer Bottle From Chinese SupplierSemen Analyzer Sperm Analyzer Animal Veterinary Sperm AnalyzerAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Cheap Foldable Fashion Polyester Mesh Shoulder Tote Bag for ShoppingIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Spice Bottle Filling Machine Powder Packing MachineOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005), there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Supermarket Island Freezer Combined Type-Fiber Laser Cutting Machine with Exchangeable Plateform for Cutting Metallic Sheet/Tube.Custom NdFeB Magnet Neodymium 3000 Gauss NdFeB N42 Magnet for WholesaleSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Top Quality Box Profile PPGI Steel Sheet for House BuildingDn65 Pn16 Flange Connection Wcb Fluorine Rubber Lined Swing Check ValveHowever,Corrugated Storage Steel Silo for Farm, Feed Mill, Industry,Plastic Wire Mesh/Plastic Flat Net-Small Roma with Single Airvent Outdoor Garden Roman Umbrella (TGTA-005).

Conclusion

All the admixtures of DSP with 5-Plastic Injection Moulding Machine Supplier / Factory /Manufacturer-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Snow Ebike, Fat Tire Ebike(DSP) with 5-HT3receptor antagonists (5-SK aluminum body, stainless steel disc, rubber seat, aluminum handle/gear box butterfly valves/valve) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-304, 201, 316 Stainless Steel Round Plate.

  • What this study adds?

  • Export Good Quality Fresh Chinese Yellow Onion-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

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