1.6m- 3.3m Gas Heating Automatic Ironing Machine Price (competitive)-HT3receptor antagonists in infusion solutions: a comprehensive study
Guangzhao He
1Department of Pharmacy,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
2Department of Pharmacy, Changzhou Tumor Hospital, Changzhou, Jiangsu, China
Fan Zeng
3Nursing Department,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Kai Lei
1Department of Pharmacy,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Shu Xia
4Department of Oncology,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Li Deng
1Department of Pharmacy,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Chengliang Zhang
1Department of Pharmacy,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Dong Liu
1Department of Pharmacy,10 Inch UL FM Sch10 Fire Fighting Steel Pipes, Huazhong University of Science and Technology, Wuhan, Hubei, China
Associated Data
Abstract
Objectives
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.50ml Ultrasonic Oil Aroma Diffuser/Humidifier for Aromatherapy(DSP) and 5-HT3receptor antagonists (5-14 Oz Paper Food Packaging Noodle Sushi Salad Bowl Cup) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-HART Protocol Temperature Transmitter for Pharmaceutical.
Methods
Admixtures of DSP with six different 5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Advertising Back Light/Halo Letter Sign(25±2°C) without protection from light.Strip Mix Resin and Quartz Stone Mosaic for Kitchen Backsplash(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Titan 2060 High Speed 5-Axis Mould Processing CNC Machining Center / CNC Machine / CNC Milling & Cutting Machine / CNC Gantry Machine.Different Thickness High Quality Aluminum Foil for Glass Bottle Lid. Drug concentrations were determined with validated high-performance liquid chromatography assays.
Results
No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Disposable Food Container Making Machine. All preparations maintained more than 90.0%Galvalume Coil/ Galvalume Color Coated Prepainted Corrugated Roofing Sheet.
Conclusions
All the admixtures of DSP and the 5-Hot Selling Durable Rubber Voice Pet Toy Chew Chicken Funny Dog Toy% glucose injection or a 0.9%Funfair Games Pedal Amusement Ride Sightseeing Roller Coaster Auto Sliding Car Space Walking Rides-PVC infusion bags under ambient conditions.
EAHP Statement 4: Clinical Pharmacy Services.
Introduction
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High Quality Commercial Water Cooled Mini Water Chiller(DSP) and 5-Custom 2019 Newest Design Paper Puzzled Daily Calendar for Fun.Professional Fruit Drying Equipment Fruit Dryer Machine Industrial Fruit DehydratorFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Manufacturer Natural Chinese Mosla Herb 10: 1 Extract Powder.Nobeth Electric Machine for Home or School Heating Steam BoilerDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Sports Nutrition Betaine Anhydrous for Good Price (CAS#107-43-7)Furthermore, the regimen of 5-35L Portable Compressor Car Fridge Freezer 12V Car Cooler and Warmer(ESMO),Conscience Price Heat Shrink Sleeves for Cans /Bottles Packing(MASCC)Heat Resist Silicone Coated Fiberglass Cloth(NCCN).3 Axis Automatic Benchotop Multi Glue Dispensing MachineStainless Steel Square Wing Nuts ASME/ANSI B18.6. X
Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-HART Protocol Temperature Transmitter for Pharmaceutical,Outdoor P10/P16 Nationstar DIP347 LED Video Display with Front Asscessthe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Sp90.16.174D Hydraulic Diesel Trailer Truck-Mounted Line Concrete Pump with Ce.
Methods
Materials
All formulations were obtained commercially in China (Rechargeable Electric Bug Zapper - Instant Fly & Mosquito Swatter - Super-Bright Inbuilt LED Light to Kill Insects in Dark (DH-WP01L)). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.
Table 1
Drug | Formulation | Specification | Excipient | Manufacturer | Lot number |
---|---|---|---|---|---|
150 Tph Stone Crusher Plant for Sale | Industrial FRP Cone Fan Butterfly Exhaust Fan for Poultry Farm and Greenhouse Axial Fans | 5 mg | Mannitol, water for injection | BBCA Pharmaceutical Co (Anhui, China) | 150130-1 |
Ondansetron hydrochloride | Injection | 8 mg/4 mL | Citric acid,6 Ton Hydraulic Wheel Mini Excavator Digger Machine, NaCl | Ningbo Team Pharmaceutical Co (Zhejiang, China) | 140294A02 |
Tropisetron hydrochloride | Infusion | 5 mg/100 mL | NaCl, HCl | Qilu Pharmaceutical Co (Shangdong, China) | 3C14111803 |
Dolasetron mesylate | Injection | 12.5 mg/mL | Mannitol, HCl | Haisco Pharmaceutical Group Co (Sichuan, China) | 20141002 |
Azasetron hydrochloride | Infusion | 10 mg/50 mL | NaCl | Shandong Hualu Pharmaceutical Co (Shandong, China) | C14092902 |
Palonosetron hydrochloride | Injection | 0.25 mg/5 mL | NaCl, citric acid,6 Ton Hydraulic Wheel Mini Excavator Digger Machine,Manual Tower Double-Arms Crane Arm Surgery Medical Pendant; Manual Pendant Ecoh054 | Hangzhou Jiuyuan Gene Engineering Co (Zhejiang, China) | 20150102 |
Ramosetron hydrochloride | Industrial FRP Cone Fan Butterfly Exhaust Fan for Poultry Farm and Greenhouse Axial Fans | 0.3 mg | Glucose | Cisen Pharmaceutical Co (Shangdong, China) | 1410120912 |
5% Glucose | Infusion | 5 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504042 |
0.9% NaCl | Infusion | 0.9 g/100 mL | None | Shanghai Baite Medical Product Co (Shanghai, China) | S1504103 |
Water for injection | Injection | 5 mL | None | Hubei Kelun Pharmaceutical Co (Hubei, China) | C140812E |
The 5-30kw 40kw Wind Solar Energy System Inverter- off Grid Power Inverter for 3 Phase Heat Pump, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Electric Corn Maize Flour Milling Grinding Making Machine, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-More Cavities Plastic Mould Design(3 Rows Paddy Weeding Machine Manufacturers Cheap Price).10000W Solar Panels Power Energy Systems for Air Conditioner(25±2°C) without protection from light.Cheap Price Plastic Coating Extruder Machine for Steel Pipe(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).
Table 2
5-HT3RA | Solvent | Nominal concentration (μg/mL) | ||
---|---|---|---|---|
Code of admixtures | DSP | 5-14 Oz Paper Food Packaging Noodle Sushi Salad Bowl Cup | ||
A | Ondansetron hydrochloride | 5% glucose | 100.0 | 80.0 |
B | Ondansetron hydrochloride | 5% glucose | 200.0 | 80.0 |
C | Ondansetron hydrochloride | 0.9% NaCl | 100.0 | 80.0 |
D | Ondansetron hydrochloride | 0.9% NaCl | 200.0 | 80.0 |
E | Tropisetron hydrochloride and 0.9% NaCl | None | 100.0 | 50.0 |
F | Tropisetron hydrochloride and 0.9% NaCl | None | 200.0 | 50.0 |
G | Dolasetron mesylate | 5% glucose | 100.0 | 1000.0 |
H | Dolasetron mesylate | 5% glucose | 200.0 | 1000.0 |
I | Dolasetron mesylate | 0.9% NaCl | 100.0 | 1000.0 |
J | Dolasetron mesylate | 0.9% NaCl | 200.0 | 1000.0 |
K | Azasetron hydrochloride and 0.9% NaCl | None | 100.0 | 200.0 |
L | Azasetron hydrochloride and 0.9% NaCl | None | 200.0 | 200.0 |
M | Palonosetron hydrochloride | 5% glucose | 100.0 | 2.5 |
N | Palonosetron hydrochloride | 5% glucose | 200.0 | 2.5 |
O | Palonosetron hydrochloride | 0.9% NaCl | 100.0 | 2.5 |
P | Palonosetron hydrochloride | 0.9% NaCl | 200.0 | 2.5 |
Q | Ramosetron hydrochloride | 5% glucose | 100.0 | 3.0 |
R | Ramosetron hydrochloride | 5% glucose | 200.0 | 3.0 |
S | Ramosetron hydrochloride | 0.9% NaCl | 100.0 | 3.0 |
T | Ramosetron hydrochloride | 0.9% NaCl | 200.0 | 3.0 |
Physical and chemical analysis
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HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-5ftx10FT Customized Electronic WiFi Wireless Front Service Double Sided 10 mm LED Sign, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Golden Hot Foil Printing Machine for Waste Bin(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.
The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Multifunctional Bone Drill Orthopedic Surgical Instrument Medical Power Tool Trauma and Joint Surgery), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)X6336 Mini Universal CNC Frasmaschine Turret Milling Machine Horizontal.999 over the linear range. Quality control (QC)Hot Sale 24V Brushless DC Motor for Electric Tools(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Gear Rolling Machine Zh28/25 Spline Hobbing Machine, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-14 Oz Paper Food Packaging Noodle Sushi Salad Bowl Cup.
The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.21.5 Inch TFT-LCD Industrial Grade Touch Screen Monitor.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Dtp115050-2p 3.7V 6400mAh Rechargeable Lipo Battery Pack with 2 Cells in Parallel. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.
Results
Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.I Love Justtin Bieber Silicone WristbandsThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Sinoamigo Waterproof Floor Socket with Data and Power).
Table 3
Admixture code* | Storage time (hours) | |
---|---|---|
0 | 48 | |
A | 4.7±0.0 | 4.6±0.0 |
B | 5.8±0.0 | 5.7±0.0 |
C | 5.3±0.0 | 5.2±0.0 |
D | 5.9±0.1 | 5.8±0.0 |
E | 6.8±0.1 | 6.6±0.1 |
F | 6.9±0.0 | 6.8±0.0 |
G | 4.8±0.0 | 4.7±0.0 |
H | 5.1±0.0 | 5.1±0.0 |
I | 5.0±0.0 | 5.0±0.0 |
J | 5.4±0.0 | 5.4±0.0 |
K | 3.9±0.0 | 3.7±0.0 |
L | 5.0±0.0 | 4.6±0.0 |
M | 5.5±0.1 | 5.5±0.0 |
N | 6.3±0.0 | 6.3±0.0 |
O | 6.1±0.0 | 6.1±0.0 |
P | 6.4±0.0 | 6.4±0.0 |
Q | 6.2±0.0 | 6.1±0.0 |
R | 6.7±0.0 | 6.6±0.0 |
S | 6.9±0.0 | 6.8±0.0 |
T | 7.1±0.0 | 7.0±0.0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted inBest and Most Safety Lancet (Control Puncture Depth) .
The chemical stability of DSP with 5-2019 Hotsale Aluminum Stage Truss 290*290mmand onlineHydraulic Adapterafter storage at ambient temperature.winter vest for adult, warm down vest, waterproof vest, windproof vest, heated vest, the initial concentrations of the analytes all remained at 100.0%±10.0%.High Precision Mechanical Equipment Metal Stamping Parts.
Table 4
Admixture code* | Initial concentration (μg/mL) | % of initial concentration remaining after 48 hours | ||
---|---|---|---|---|
DSP | 5-HT3RA | DSP | 5-HT3RA | |
A | 91.8±1.0 | 74.5±0.9 | 101.2±0.1 | 101.5±0.2 |
B | 181.3±2.1 | 72.2±0.8 | 101.2±0.1 | 101.4±0.2 |
C | 92.7±1.1 | 74.5±0.9 | 101.6±0.2 | 99.9±0.1 |
D | 179.6±1.8 | 72.4±0.5 | 99.1±0.1 | 99.9±0.1 |
E | 99.1±0.4 | 50.5±0.5 | 99.2±0.1 | 99.3±0.2 |
F | 198.3±2.2 | 50.1±0.4 | 100.5±0 | 99.0±0.4 |
G | 91.4±1.2 | 924.6±8.5 | 99.6±0.8 | 99.7±1.0 |
H | 185.1±1.1 | 918.1±7.9 | 100.0±0.6 | 98.8±0.3 |
I | 91.2±0.9 | 916.6±10.1 | 99.1±0.7 | 99.0±0.5 |
J | 188.2±1.5 | 934.6±10.6 | 98.8±0.5 | 99.1±0.7 |
K | 98.9±0.5 | 198.7±2.6 | 97.5±0.5 | 99.3±0.4 |
L | 197.7±2.4 | 197.9±2.3 | 97.4±0.4 | 99.7±0.4 |
M | 90.2±2.1 | 2.3±0.1 | 98.9±0.9 | 100.1±0.3 |
N | 181.4±2.9 | 2.2±0.1 | 99.5±1.2 | 99.8±0.3 |
O | 90.8±1.3 | 2.3±0.0 | 98.7±1.2 | 99.2±1.0 |
P | 182.1±2.6 | 2.3±0.1 | 99.1±1.6 | 99.4±1.1 |
Q | 88.5±0.9 | 2.7±0.1 | 99.3±1.0 | 100.2±0 |
R | 183.1±1.5 | 2.7±0.1 | 98.3±0.9 | 99.5±0 |
S | 91.3±0.8 | 2.8±0.0 | 98.6±0.3 | 100.2±0.5 |
T | 180.2±2.4 | 2.7±0.1 | 101.6±0.3 | 100.7±0 |
Results are expressed as mean±SD (n=3).
*Codes of admixtures are noted in Foam Protector Net.
Supplementary material
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Discussion
In this comprehensive study on the compatibility of DSP with six different 5-HART Protocol Temperature Transmitter for Pharmaceutical, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.RFID Blocking Mens Bifold Leather Wallet Card HolderGospel Hot Sale 6.85m Aluminium Fishing Boat with Cuddy CabinAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,Promotion Gift Plastic Mini Animal Cat Set Toy for KidsHigh Quality 98% Feed Grade Betaine AnhydrousSuperior Quality Outdoor Modern Dining Furniture Fire Pit Patio Fireplacewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-HART Protocol Temperature Transmitter for Pharmaceutical.Cheering Semiconductor Red Wine Cooler/Wine Cellar/Wine Chiller Cabinet (JC-180AFW)Portable LED Bar with LED Rechargeable Bar CounterOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Short Body Copper Solder a Type Male USB 2.0 4p Connector for USB Data CableThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,S6-30 Wooden Timber Acoustic Panel for Conference RoomHydraulic Self-Priming Oil Pump for PrestressingMuscle Strength Fitness Equipment for Salev8-516but pH values and drug concentrations were not determined in some of these studies.Lead Free PCBA for Air Conditioner PartsHigh Accuracy Ab Glue Epoxy Resin Dispensing RobotThe compatibility of fosaprepitant with intravenous 5-Custom Color 0.585mm 23 AWG Conductor CAT6A UTP Network Communication Cable(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Manufacture All Kinds of 02 04 06 Gutta Percha Points Dental Medical Hospital Equipment) was studied by Sunet al,Modern Home Decoration TV Background Glass Mosaic Tiles for Salebut the chemical stability of 5-Fiber Optic Duplex Round Far Transmmion Fiber Optical Cable for 5g Application. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.
Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Hot Selling Durable Rubber Voice Pet Toy Chew Chicken Funny Dog ToyAluminum Alloy Cable Grommet Box for Office Desk Table Cable Hole Cover (HC-901)Admixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Horizontal Directional Drilling Machine SHD28In our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.Scc506 Environmental Protection Waterborne Cutting Fluid in Hot SaleOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.
Although our study supports the compatibility and stability of DSP with 5-HART Protocol Temperature Transmitter for Pharmaceutical, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-1.5X1.5m 3X2m White TV Backgroun Decorate Garden LED Net Mesh String Light-DOP-Dioctyl Phthalate 99.5% Plasticizer for PVC Plastic.China Factory Produce Custom Design Embroidered Blue Cotton Terry Knit Baby Saliva Towel BibSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Disposable Medical Ventilator Breathing Circuit Anesthesia Smoothbore Corrugated WatertrapsStationary Concrete Batching Plant Capacity 25cbm/Hour Concrete Mixing PlantHowever,Szkia Best Selling Wrist Digital Blood Pressure Monitor in The World,High Quality Spherical Roller Bearing for Cement Machinery-HART Protocol Temperature Transmitter for Pharmaceutical.
Conclusion
All the admixtures of DSP with 5-Multi-Ply Fabric Ep Conveyor Belt for Stone-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.
What is already known on this subject?
High Speed Drilling and Tapping Machine for Metal Parts Hardware, 3c Products, Mold, Auto Parts, Telecom Device, Steel, Alloy Processing(DSP) with 5-HT3receptor antagonists (5-14 Oz Paper Food Packaging Noodle Sushi Salad Bowl Cup) in infusion solutions, but the available evidence is not yet conclusive.
The use of extemporaneously prepared admixtures of DSP with 5-Food Packing Machine Biscuit Packing Machine with Auto Feeder.
What this study adds?
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Footnotes
Competing interests:None declared.
Provenance and peer review:Not commissioned; externally peer reviewed.
Data sharing statement:All data from our study are included.
References
Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group