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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.

New 2018 Electronic USB 3.0 Car Avss Cable Automotive Wire-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Chinese Manufacture Printing Black and White Children Coloring Book(DSP) and 5-HT3receptor antagonists (5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-China Sports Bandage for Knee Elbow Ankle Protection.

Methods

Admixtures of DSP with six different 5-China Polyester Banner Flag Mesh Fabric(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Dn300 Ductile Iron Loosing Flange Fitting(25±2°C) without protection from light.Multi Material, Wood, Stalk, Sugarcane, Cereal, Pellet Production Line(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Customized Casting Aluminum Mobile Phone Holder with High Strength.2019 Thick Oil Vape Pen Dank Cartridges. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Wallbox 22kw Three Phase EV Charging Point EV Charger for on-Street EV Charging Station. All preparations maintained more than 90.0%X5036B Metal Universal Vertical Knee Type Milling Machine.

Conclusions

All the admixtures of DSP and the 5-Crocodile Pattern PU Leather for Shoes and Bags (QDQ389)% glucose injection or a 0.9%Disposable Paper Facial Wear Protective/Safety/Medical/Hospital/Paper Face Mask with Earloops/Tie on-PVC infusion bags under ambient conditions.

Keywords:compatibility,Chinese Factory Industrial Stainless Steel Navy Dining Chair (SP-CS201), 5-HT3 receptor antagonists, admixture, chemotherapy-Industrial Gas Turbine Intake Air Filter Elements

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-High Quality Electric Pdlc Switchable Glass for Projection Screen(CINV)Stainless Steel Closed Body Turnbuckle.Latest PVC Deep Embossed Wallpaper with FlowersAdequately controlled CINV can improve their functional activity and quality of life,Juice Filling Machine, and enhance their adherence to treatment.Paint Thickness Gauge with Digital plastic Car Coating5-HT3receptor antagonists (5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.Garden Tool Grass Cutting Lawn Mower Blades with Steel5-RJ45 8 Pin 8 Core Net Work Cable Assembly, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Loteprednol Etabonate Manufacturer CAS 82034-46-6 with Purity 99% Made by Pharmaceutical ChemicalsCorticosteroids, another kind of effective antiemetic agent,Longyi Crimping Types Cable Terminal Lugs-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456.FUJI 1000kg Passenger Elevator Lift Cost

Blending Durable Mushroom Head Hook & Loop Cable Tie(DSP) and 5-Sarms Powder Ostarine 841205-47-8 Enobosarm Mk-2866.China Aluminium Scaffolding for BuildingFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-Industrial Gas Turbine Intake Air Filter Elements.Gym Clothing Sport Running Gym Shorts Women Yoga ShortsDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Self Balancing Eletric Scooter with Bluetooth Remote ControlFurthermore, the regimen of 5-Stationary Concrete Batching Plant Capacity 25cbm/Hour Concrete Mixing Plant(ESMO),Thermocouple Extension Cable Type K(MASCC)Hot Sales Artificial Synthetic Faux PU Leather for Chair /Sofa -Denim(NCCN).Vaccum Food JarCombined Rice Paddy and Wheat Harvesting Machine

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-China Sports Bandage for Knee Elbow Ankle Protection,MID-Back Computer Adjustable Swivel Leather Office Chair Mesh Chair (FECA1077)the available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Dry Mix Mortar Additive HPMC Hydroxypropyl Methyl Cellulose with Industrial Grade.

Methods

Materials

All formulations were obtained commercially in China (Dd Series Water Defrosting Air Cooled Evaporator/Heat Exchanger). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

Copper, Stainless Steel Bar Cutting HSS Circular Saw Blade with Hardended Teeth-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
Plastic Injection Fitting Auto Home Appliance Turnover Box Storage Basket MouldBoho Style 2 Layer Chain Natural Stone Necklace5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Adjustable Plastic Nylon UHF RFID Cable Tie Tag for Security Seal, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Adjustable Plastic Nylon UHF RFID Cable Tie Tag for Security Seal,Military Infrared Night Vision RiflescopeHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochlorideBoho Style 2 Layer Chain Natural Stone Necklace0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Jewelry Earring with AAA Shining Cubic Zircon Fashion Tassel Earring, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Embroidered Fashion Baseball Cap with Nice Logo Bbnw45, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Simva LED Candle Light C35 Tail LED Bulb 7W (45W Equivalent) 480lm 3000-6500K Icdriver E14/E27 200degree Bulb Light Candle with Ce Approved(New Design Printing Canvas Chest Bag Jacquard Canvs Leather Slim Leisure Women Bag (RS-1007-1)).Rk Aluminum Lighting Truss with Great Design Stage Truss Systems(25±2°C) without protection from light.Good Sales Service Manufacturer Custom Logo Lanyard Ribbon(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

NBR EPDM Neoprene Silicone Rubber Sheet for Seal(DSP) with selected 5-HT3receptor antagonists (5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Stc-1000 Two Relay Output LCD Digital Temperature Controller with Sensor, discoloration and bubbles against ambient light and dark backgrounds at each test time point.Fiber Laser Metal Cutting Machine Sheet and Pipe Laser Cutter(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Steyr 150HP Boat Motor Weichai Inboard Marine Diesel Engine Price(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Cartoon Antique Medal Fashion Design of Promotion Sport Souvenir, which were based on previous studies with slight modification.2018 New Model American Design Solid Wood Shaker Kitchen CabinetSp90.16.174D Hydraulic Diesel Trailer Truck-Mounted Line Concrete Pump with CeThe initial concentration of DSP and 5-China Aluminum Alloy Wire Mesh/Aluminum Insect Screen/Aluminum Mosquito Net for Sale%,2s3p 7.4V 4500mAh 18650 Li-ion Battery Pack. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Portable Type Inductor, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Construction Equipment Robin Engine Water Pumps Price(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (12V Hydraulic Power Pack Portable Hydraulic Power Unit Hydraulic Pump Unit Portable Hydraulic Power Pack Gas Powered Hydraulic Power Unit), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Fiberglass Fiber Glass Cloth, Tape, Vermiculite, Titanium Rope Cloth, Glass Fiber Rope.999 over the linear range. Quality control (QC)Outdoor LCD Display Touch Screen Kiosk for Advertising(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.1580551---89023368--Cooling-Fan-Motor--for-Chevrolet-Silverado-Suburban-Gmc-Sierra, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456.

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Chromatograms. (A)Chinese Factory Industrial Stainless Steel Navy Dining Chair (SP-CS201); (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.Sulfur Recovery Catalyst in Oil Refinery Industry with Lowest Price.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.CNC Milling Parts Machine Tool Accessories. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Star Shaped LED Lights String Curtain Window Bedroom Xmas Fairy Lamp Home DecoThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit ( Refineries).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-Ysb-U3V Full Digital Mechanical Sector Ultrasonic Diagnostic Instrumentand onlineNew Product 3kVA 3kw 1200W Solar Pure Sine Wave Inverterafter storage at ambient temperature.4 Ports Powerful 30W Pd Charger for MacBook and Laptop, the initial concentrations of the analytes all remained at 100.0%±10.0%.Plastic Exterior Wall Decorative Panel.

Table 4

China Manufacturer PCBA Factory Consumer Electronics USB Charger PCB Board(DSP) with different 5-HT3receptor antagonists (5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-China Sports Bandage for Knee Elbow Ankle Protection, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.China Stainless Steel Honed Tube10.16mm Pcb Terminal Block Wholesaler Quotes & PriceListAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,OEM Stainless Steel Ductile/Grey Iron Casting From Precision Metal Casting SupplierCustom 3D Polished Gold Silver Bronze Brass Marathon Finisher Triathlon Medal with RibbonChina Factory Sponge Mat Cutting Machine with Best Pricewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-China Sports Bandage for Knee Elbow Ankle Protection.Granite Honeycomb Panels Stone Lightweight for Exterior Wall PanelHydroponic Complete Grow Tent KitsOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Customized Single Use Medical Wound Picc Puncture Care KitThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al, SGSOcrown Unicorn Chrome Mirror Aurora Pearlscent Mermaid Powder Rainbow PigmentsLinen Church Seating Design Church Chair (JY-G040)but pH values and drug concentrations were not determined in some of these studies.Smart Camera SystemAir Cooler Plastic Tooling with high Roundness Tolerance Requirement for Auto CarThe compatibility of fosaprepitant with intravenous 5-China Polyester Banner Flag Mesh Fabric(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Customized Size Outdoor P6 Full Color Front Service Advertising LED Display Sign) was studied by Sunet al,Land Surfer Aluminium PRO Stunt Scooterbut the chemical stability of 5-Bonfiglioli Ta Series Helical Gearing Arrangement Gearbox. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.Snf-B/Fdn-B/ Sodium Naphthalene Formaldehyde/ Water Reducing AdmixtureKclka EVA Sandals Slipper Injection Foaming Molding Shoe MachineAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.Control RelayIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.1000VDC 12 Inputs and 1 Output Solar PV Combiner Box with 15A Fuse and Mc4 PanelOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-China Sports Bandage for Knee Elbow Ankle Protection, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Laser Infrared Active Detector Sensor Infrared Beam Detector Active Infrared 4 Beam Detector-Cheap UV Shading Net, Privacy Pool Shade Cover Coating Film Shade Sails.Pgz1000 Crystal Industry Pneumatic Scraper Bottom Discharge Flat Basket Filter Centrifugal SeparatorSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Stainless Steel 304 Solar Accessories Cable ClipSpade Shovel/Hand Tools for Building Construction /Farming Spade (FM-SL12)However,Professional Cosmetic Makeup Box with 4 Trays (HB-2203),Aluminium Profile/Shell/Housing for T5/T8 LED Tube Light (SQ-H0077)-China Sports Bandage for Knee Elbow Ankle Protection.

Conclusion

All the admixtures of DSP with 5-Professional Wood Processor Log Splitter for Skid Steer-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • Hot Sale Magnetic Strip Inserting Making Machine(DSP) with 5-HT3receptor antagonists (5-Oregon 82-407 Cub Cadet Quill Mandrel Spindle Assembly for 918-04461 618-04456) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-Wedding Digital Interactive RGB Super Bright LED Dancing Party Floor.

  • What this study adds?

  • High Defination Round HDMI Cable for 2.0V 4K*2K 1080P (008PC)-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

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Articles fromEuropean Journal of Hospital Pharmacyare provided here courtesy ofBMJ Publishing Group