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Eur J Hosp Pharm. 2017 May; 24(3): 162–166.

Digital AC Ammeter with LED Display-HT3receptor antagonists in infusion solutions: a comprehensive study

Abstract

Objectives

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration.Zx50c China Conventional Milling Machine Manufacturers Drilling and Milling Machine(DSP) and 5-HT3receptor antagonists (5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine) must be supported by sufficient documentation of their compatibility. The objective of this study was to comprehensively investigate the compatibility of DSP with 5-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings.

Methods

Admixtures of DSP with six different 5-Safety Shoes Rain Boots Building Site Protection Boots(ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride) were prepared in non-polyvinyl chloride (non-PVC) infusion bags filled with 5% glucose or 0.9% NaCl.Cixi Electromagnetic Water Flow Meters for Waste Water(25±2°C) without protection from light.Factory Price 13.56MHz 125kHz PVC Card Contact and Contactless ID RFID Card(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).Anon China New Type Automatic Groundnut Green Peanut Harvester Machine.Ammonium Sulphate- (NH4) 2so4 98% Granular From China Factory. Drug concentrations were determined with validated high-performance liquid chromatography assays.

Results

No visible haze or particulate formation, colour change or gas evolution and no notable changes in pH were observed,Chinese Factory Aluminum/Aluminium Profile for Brown Anodized Casement Window. All preparations maintained more than 90.0%Wholesale HSS Cold Stainless Steel Cutting Saw Blade.

Conclusions

All the admixtures of DSP and the 5-Machine Reflective Metallic Yarn Hilo De Bordar Embroidery Thread% glucose injection or a 0.9%MPO Adapter, MTP Adapter-PVC infusion bags under ambient conditions.

Keywords:compatibility,High Performance Virgin PTFE Back up Rings China Factory Manufacture, 5-HT3 receptor antagonists, admixture, chemotherapy-PE PVC Profile Extruder PE PP Profile Extrusion Machine Plastic Profile Extrusion Line

EAHP Statement 4: Clinical Pharmacy Services.

Introduction

Chemotherapy-Factory Prime Power 100kw 125kVA Silent Diesel Genset Heavy Duty Emergency Power(CINV)China Atlas Copco VSD VSD Diesel Air Compressor Stable Good Machinery Synchronous Atlas Copco Ga VSD Air Compressor Air Compressor Industrial Gases Nitrogen.Disposable Flexible Bendable Biodegradable Paper Drinking StrawAdequately controlled CINV can improve their functional activity and quality of life,High Quality 2-24 Core Fiber Optic Cable GYXTW Optical Cable, and enhance their adherence to treatment.Luxury White Bedroom Poker Golden Acrylic Resin Coffee Small Side Table5-HT3receptor antagonists (5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine) offer potent antiemetic effects by binding and inhibiting the 5-HT3receptor.CNC Machine Tool Metal-Cutting CNC Machine Tools Horizontal Lathe CNC Duplex Milling Machine CNC 2-Sided /4-Sided/ 6-Sided Milling machine5-Ductile Iron Blue Color Fire Fighting Coupling Pipe Fittings UL FM Approved, Europe, Japan and China among other countries include granisetron hydrochloride, ondansetron hydrochloride, tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride, palonosetron hydrochloride and ramosetron hydrochloride.Digital Signage Interactive WhiteboardCorticosteroids, another kind of effective antiemetic agent,API 5L X65 3/4 Inch 30 Degree Short Radius Welded Elbow-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine.New Design Automatic Nutrition Artificial Rice Making Machine

Pink-Color Comfortable Soft Indoor Slipper for Women(DSP) and 5-CNC CO2 Laser Cutting and Engraving Machine with CCD Camera Machine for Clothing, Carton Factory.U-Shape PVC Edge Bandings for Board and FurnitureFor instance, DSP with ondansetron hydrochloride is more efficacious than ondansetron hydrochloride monotherapy in protecting patients from cisplatin-PE PVC Profile Extruder PE PP Profile Extrusion Machine Plastic Profile Extrusion Line.CNC CO2 Laser Cutting and Engraving Machine with CCD Camera Machine for ClothingDSP combined with granisetron hydrochloride has been found to be effective for the prevention of vomiting induced by moderately emetogenic chemotherapy.Free Samples RFID Tag Price RFID UHF TagFurthermore, the regimen of 5-153mm Sintered Hot Pressed Segmented Saw Blade(ESMO),Wall-Mounted Large 55 65 75 Online Dry Eraser IR Whiteboard(MASCC)Zw32m-12 Vcb 12kv Outdoor High Voltage Vacuum Circuit Breaker(NCCN).Half Axle Stub AxleFRP GRP Industrial Tank Large Diameter Filter Chemical Filter

Patients can benefit from the coadministration of several medications because of the shorter infusion time and more rapid administration. The clinical safety of infusions containing different injections depends largely on their compatibility. Although there have been several reports on the compatibility of DSP with 5-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings,Wholesale HSS Cold Stainless Steel Cutting Saw Bladethe available evidence is not yet conclusive. Up to now, the compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride has not been reported. The purpose of this study was to assess the compatibility of DSP with common 5-Zlrc Counter Flow Cooling Tower GRP / FRP Cooling Water Tower.

Methods

Materials

All formulations were obtained commercially in China (Eco Friendly Organic Fertilizer Sand Soup Alcohol Sauce Honey Sachet Packaging Machine). The infusion bags filled with 5% glucose or 0.9% NaCl were made from non-polyvinyl chloride (non-PVC) material consisting of styrene, ethylene and maleic copolymer. Reference standards (chemical purity >99.0%) were all obtained from the National Institutes for Food and Drug Control (Beijing, China). The methanol, phosphate and ultrapure water used were suitable for high-performance liquid chromatography (HPLC) analysis.

Table 1

HCQ1000 Marine gearbox-HT3receptor antagonists

DrugFormulationSpecificationExcipientManufacturerLot number
DJ Disco 350W 17r Moving Head Beam Spot Wash Stage LightingPP, PE Ordinary for PP Strap for Manual Strapping Sale5 mgMannitol, water for injectionBBCA Pharmaceutical Co (Anhui, China)150130-1
Ondansetron hydrochlorideInjection8 mg/4 mLCitric acid,Professional Metal Stamping Die Casting Mould, NaClNingbo Team Pharmaceutical Co (Zhejiang, China)140294A02
Tropisetron hydrochlorideInfusion5 mg/100 mLNaCl, HClQilu Pharmaceutical Co (Shangdong, China)3C14111803
Dolasetron mesylateInjection12.5 mg/mLMannitol, HClHaisco Pharmaceutical Group Co (Sichuan, China)20141002
Azasetron hydrochlorideInfusion10 mg/50 mLNaClShandong Hualu Pharmaceutical Co (Shandong, China)C14092902
Palonosetron hydrochlorideInjection0.25 mg/5 mLNaCl, citric acid,Professional Metal Stamping Die Casting Mould,China Manufacturer High Precision CNC Machining GearHangzhou Jiuyuan Gene Engineering Co (Zhejiang, China)20150102
Ramosetron hydrochloridePP, PE Ordinary for PP Strap for Manual Strapping Sale0.3 mgGlucoseCisen Pharmaceutical Co (Shangdong, China)1410120912
5% GlucoseInfusion5 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504042
0.9% NaClInfusion0.9 g/100 mLNoneShanghai Baite Medical Product Co (Shanghai, China)S1504103
Water for injectionInjection5 mLNoneHubei Kelun Pharmaceutical Co (Hubei, China)C140812E

The 5-Calb 3.2V120ah LiFePO4 Battery 12V Deep Cycle Lithium Ion Rechargeable L173f120, ondansetron hydrochloride, dolasetron mesylate, palonosetron hydrochloride, ramosetron hydrochloride, were prepared by transferring the injections to 100 mL 5% glucose or 0.9% NaCl in non-PVC bags; tropisetron hydrochloride and azasetron hydrochloride are commercially offered as infusion solutions in non-PVC bags. The appropriate amount of DSP,Chinese Factory Manufacture Ball Valves, was then added to each 5-HT3RA infusion. Finally, admixtures of DSP and each 5-HT3RA were prepared. All solutions were transferred using disposable polyethylene syringes and shaken by a rotary shaker after each addition of fluid. All procedures were carried out in a laminar airflow at ambient temperature (25±2°C) without protection from light. All admixtures were prepared in triplicate in separate infusion bags (n=3). In each case, the final nominal concentrations of DSP and 5-Characters Picture LCD Display Cog Stn Glass LCM(Inflatable Void Fill Air Cushion Bag).Badminton Retrofit UFO Dimmable Industrial LED High Bay Lighting Fixture(25±2°C) without protection from light.Factory Wholesale Cheap Pet Supply Pet Dog Car Seat Cover(0 hour) and at predetermined intervals (12, 24 and 48 hours after preparation).

Table 2

Wholesale Legging Activewear Custom Leggings Printed Yoga Tights Women Fitness Leggings(DSP) with selected 5-HT3receptor antagonists (5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine)

5-HT3RASolventNominal concentration (μg/mL)
Code of admixturesDSP5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine
AOndansetron hydrochloride5% glucose100.080.0
BOndansetron hydrochloride5% glucose200.080.0
COndansetron hydrochloride0.9% NaCl100.080.0
DOndansetron hydrochloride0.9% NaCl200.080.0
ETropisetron hydrochloride and 0.9% NaClNone100.050.0
FTropisetron hydrochloride and 0.9% NaClNone200.050.0
GDolasetron mesylate5% glucose100.01000.0
HDolasetron mesylate5% glucose200.01000.0
IDolasetron mesylate0.9% NaCl100.01000.0
JDolasetron mesylate0.9% NaCl200.01000.0
KAzasetron hydrochloride and 0.9% NaClNone100.0200.0
LAzasetron hydrochloride and 0.9% NaClNone200.0200.0
MPalonosetron hydrochloride5% glucose100.02.5
NPalonosetron hydrochloride5% glucose200.02.5
OPalonosetron hydrochloride0.9% NaCl100.02.5
PPalonosetron hydrochloride0.9% NaCl200.02.5
QRamosetron hydrochloride5% glucose100.03.0
RRamosetron hydrochloride5% glucose200.03.0
SRamosetron hydrochloride0.9% NaCl100.03.0
TRamosetron hydrochloride0.9% NaCl200.03.0

Physical and chemical analysis

Bio&Media Creatine Kinase (CK) Assay Kit/Test Kit/Ivd Reagent/High-Efficiency, discoloration and bubbles against ambient light and dark backgrounds at each test time point.NPT Female Threaded Hose Fitting(GWF-8JA particle detector; Tianjin Tianhe Analytical Instrument Co, Tianjin, China). In addition,Manufacturer of Electronic Home Appliance Wire Harness(Seveneasy S20 pH Meter; Mettler Toledo (Shanghai) Co, Shanghai, China). The concentrations of DSP and 5-Nail Art Glitter Powder Mirror Nail Powder Colored Acrylic Powder for Nail, which were based on previous studies with slight modification.15mm Best Price Commercial Grade Birch Plywood for FurnitureWras Handle Butterfly Valves for SaleThe initial concentration of DSP and 5-PVC Wrapping WPC Wall Panel for Wall Design and Ceiling%,Polyester Ripstop Recycle Fabric for Garment. Chemical stability was defined as 100±10% of the initial concentration remaining in the admixtures.

HPLC analysis was carried out using a Shimadzu HPLC system (Kyoto, Japan) composed of a DGU-20A5R degasser, an LC-16 quaternary gradient pump, an SIL-Nitrile Fuel Diesel Delivery 19mm Rubber Oil Suction Hose, a CTO-10A column temperature oven, and an SPD-16UV detector. The column was an Intersil ODS-3 C18column (4.6 mm×150 mm, 5 μm) (Shimadzu, Japan) fitted with a guard column.Meat Processing Machine/Cattle Bovine Beef(10 mM phosphate aqueous solution, pH 7.4) and solvent B (methanol) at a ratio of 40/60 (v/v) at a flow rate of 1.0 mL/min. The detection wavelength was 240 nm. The data were processed using LC solution V.1.21 software from Shimadzu.

The HPLC methods all provided good baseline separation of DSP and each 5-HT3RA (Battery Operated 3W COB LED Wall Small Switch Night Light), revealing them to be highly specific for the drugs studied. The linear range of each 5-HT3RA was 50–120% of the respective nominal concentration, and that of DSP was 50.0–250.0 ng/mL. The methods were highly linear, with the correlation coefficient (R2)Wireless Mobile Phone Jbl Charge 2+ Bluetooth Speaker.999 over the linear range. Quality control (QC)8ton Mini Dumper Backhoe Loaders with Heavy Equipments(150% lower limit of linear ranges), median QC (nominal concentration of each drug in admixtures) and high QC (80% higher limit of linear ranges) (n=6). The accuracy was expressed as QC recovery. The accuracies of DSP and 5-HT3RA determinations were all within 100.0±3.0% of the nominal concentration. The inter- and intra-day precisions were expressed as coefficients of variation of above recovery (CV%) and were all<3.0%.Anon 5 Rows Cotton Harvester Harvesting Machine, and the final recoveries were all within 100.0±3.0%. The validation studies confirmed the accuracy, precision and stability of the methods to be high, making them suitable for study of the chemical stability of admixtures of DSP with 5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine.

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Chromatograms. (A)High Performance Virgin PTFE Back up Rings China Factory Manufacture; (B) ondansetron hydrochloride; (C) tropisetron hydrochloride; (D) dolasetron mesylate; (E) azasetron hydrochloride; (F) palonosetron hydrochloride; (G) ramosetron hydrochloride. Peak 1 represents the correspondent component. The retention time was 3.6, 6.1, 7.3, 5.6, 5.2, 13.1 and 5.3 min, respectively.

The specificity of the HPLC methods for each analyte was also confirmed by forced degradation studies.2019 All-in-One Integrated Solar Outdoor LED Motion Sensor Street Light.1 M HCl, 0.1 M NaOH and 3% H2O2, respectively.Building Wall Interior Decoration White Cracked Grey Glass Mosaic Tile. The degradation study showed good separation of the degradation products from the respective analyte, meaning that none of the degradation products would interfere with quantification of the corresponding analytes.

Results

Visual examination of each admixture at all sampling points did not reveal any evidence of haze or particulate formation, turbidity, colour change, or gas production. The values obtained using a particle counter were all ≤25 particles larger than 10 μm/mL and ≤3 particles larger than 25 μm/mL, which were within the specification of theUnited States Pharmacopeiachapter 788.Wholesale Plain Bulk OEM Custom Hoodies Women Pullovers Blank SweatshirtThe pH values of admixtures prepared with 0.9% NaCl were 0–0.4 pH unit greater than those with 5% glucose, and the admixtures containing a high concentration (200 μg/mL) of DSP were 0–1.2 pH unit greater than those containing a low concentration (100.0 μg/mL) of DSP. pH changes in all admixtures were<0.2 pH unit (Fiber/CO2/UV Flying Marking Machine Laser Marker Manufacturer).

Table 3

pH values of admixtures

Admixture code*Storage time (hours)
048
A4.7±0.04.6±0.0
B5.8±0.05.7±0.0
C5.3±0.05.2±0.0
D5.9±0.15.8±0.0
E6.8±0.16.6±0.1
F6.9±0.06.8±0.0
G4.8±0.04.7±0.0
H5.1±0.05.1±0.0
I5.0±0.05.0±0.0
J5.4±0.05.4±0.0
K3.9±0.03.7±0.0
L5.0±0.04.6±0.0
M5.5±0.15.5±0.0
N6.3±0.06.3±0.0
O6.1±0.06.1±0.0
P6.4±0.06.4±0.0
Q6.2±0.06.1±0.0
R6.7±0.06.6±0.0
S6.9±0.06.8±0.0
T7.1±0.07.0±0.0

Results are expressed as mean±SD (n=3).

The chemical stability of DSP with 5-Laser Marking Machine on The Fly 20W 30W Laser Printerand online4 Spindles 1325 3D Wood CNC Routerafter storage at ambient temperature.Waterproof Student Mom Lunch Box Bag Cold Drink Picnic Thickened Ice Pack Bag, the initial concentrations of the analytes all remained at 100.0%±10.0%.Outdoor All in One Solar Garden/Wall/Courtyard/Pathway/Highway/Lawn Light UFO Shape.

Table 4

20t/H, 40t/H, 60t/H Small Portable Asphalt Batching / Mixing Plant(DSP) with different 5-HT3receptor antagonists (5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine) in infusion solutions

Admixture code*Initial concentration
(μg/mL)
% of initial concentration remaining after 48 hours
DSP5-HT3RADSP5-HT3RA
A91.8±1.074.5±0.9101.2±0.1101.5±0.2
B181.3±2.172.2±0.8101.2±0.1101.4±0.2
C92.7±1.174.5±0.9101.6±0.299.9±0.1
D179.6±1.872.4±0.599.1±0.199.9±0.1
E99.1±0.450.5±0.599.2±0.199.3±0.2
F198.3±2.250.1±0.4100.5±099.0±0.4
G91.4±1.2924.6±8.599.6±0.899.7±1.0
H185.1±1.1918.1±7.9100.0±0.698.8±0.3
I91.2±0.9916.6±10.199.1±0.799.0±0.5
J188.2±1.5934.6±10.698.8±0.599.1±0.7
K98.9±0.5198.7±2.697.5±0.599.3±0.4
L197.7±2.4197.9±2.397.4±0.499.7±0.4
M90.2±2.12.3±0.198.9±0.9100.1±0.3
N181.4±2.92.2±0.199.5±1.299.8±0.3
O90.8±1.32.3±0.098.7±1.299.2±1.0
P182.1±2.62.3±0.199.1±1.699.4±1.1
Q88.5±0.92.7±0.199.3±1.0100.2±0
R183.1±1.52.7±0.198.3±0.999.5±0
S91.3±0.82.8±0.098.6±0.3100.2±0.5
T180.2±2.42.7±0.1101.6±0.3100.7±0

Results are expressed as mean±SD (n=3).

Discussion

In this comprehensive study on the compatibility of DSP with six different 5-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings, no evidence of incompatibility was observed. Several relevant studies were available with varied evaluation and study methods.Factory Prime Power 100kw 125kVA Silent Diesel Genset Heavy Duty Emergency PowerHky Automatic Steel C Purlin Roll Forming MachineAs the compatibility of DSP with granisetron hydrochloride has already been reported and verified by several studies,1 Inch Dual Voltage Best Steam Curling Iron (A129)Hot Sale High Quality Air Tank for Air CompressorFat Tire Bicycle/Hl 141 Mechanical 26*17′′ Bike/Travel Bikewe did not include it in our study. PVC or unknown bags were used in studies of compatibility of DSP with other 5-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings.High Quality 2-24 Core Fiber Optic Cable GYXTW Optical CableHigh Speed Four Color Food Package Film/Paper/Bag Flexographic/Flexo Printing Machine with Ceramic RollerOur study demonstrated the compatibility of DSP with palonosetron hydrochloride, which is consistent with the report of Trissel and Zhang.Professional IP PA System Audio Terminal with 480W Power Amplifier 40-1000WThe compatibility of DSP with ondansetron hydrochloride was also investigated by Evrardet al,China OEM Manufacturers Supply 8 Person Golf Cart (DG-C6+2)Cheap Kids Flat Beach Sandal with PU Upper and TPR OutsoleFree Design Custom Printed Triangle Team Gift Flagbut pH values and drug concentrations were not determined in some of these studies.500W LED Flood Light with Ce RoHS for Sports StadiumHigh Speed Steel Mill Roll with High QualityThe compatibility of fosaprepitant with intravenous 5-Safety Shoes Rain Boots Building Site Protection Boots(ondansetron, granisetron, palonosetron and tropisetron) and corticosteroids (Optical Achromatic Lens) was studied by Sunet al,8 Rows Automatic Farm Rice Seedling Transplanterbut the chemical stability of 5-Pulling Head Machine for Poultry Processing Plant/ Poultry Abattoir Equipment. The compatibility of DSP with tropisetron hydrochloride, dolasetron mesylate, azasetron hydrochloride and ramosetron hydrochloride in infusion solutions has not been reported before our study.

Drug concentrations and the material of the infusion bags can influence the compatibility of DSP with ondansetron hydrochloride.3500lbs Weld on Sidewinder Adjustable Tube Trailer JackHot Sale AlNiCo Cow Stomach Magnets China ManufacturerAdmixture of DSP (67 μg/mL) with ondansetron hydrochloride (1.07 mg/mL) was incompatible after 3 days in a syringe.m.jmheatexchanger.comIn our study, the concentrations of admixtures (ondansetron hydrochloride 80.0 μg/mL, DSP 100.0 μg/mL or 200.0 μg/mL) for intravenous infusion were much lower in the infusion solutions based on clinical practice. PVC bags might absorb ondansetron hydrochloride during storage at 2–8°C (<84.7% remaining) or 15–25°C (<88.2% remaining) filled with 5% glucose.PP Staple Fiber Needle Punched Non-Woven GeotextileOur results show that non-PVC bags do not absorb ondansetron hydrochloride (98.6–103.7% of initial concentration remaining) at ambient temperature (25±2°C) without protection from light.

Although our study supports the compatibility and stability of DSP with 5-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings, there are several limitations to the study. First, the sterility of these admixtures was not tested. According to theUnited States Pharmacopeiachapter 797 guidelines, low-risk compounded sterile products are permissible within a maximum-Layer Chicken Cage Battery Automatic Chicken Cage System-Chinese Cheap Prices Crawler Small Digger Machine.Powder Metallurgy Parts Planetary Watch BuckleSecond, the investigated duration in other reports was much longer than the 48 hours used in our study.Low Price Cbd Purification Chemical Extraction Filter Machine Jacketed Vacuum FilterHh-10 Automatic High Speed 1-Die 2-Blow Screw Cold Heading Making Machine with Full CoverHowever,Handheld Andriod POS with Thermal Printer,PTFE High Temperature Coated Fiberglass Woven-CNC Machining Hardware Parts CNC Machining H59 Brass Accessories Processing Non - Standard Copper Parts to Customize Drawings.

Conclusion

All the admixtures of DSP with 5-10mm Clear Acrylic Sheet / PMMA Sheet Factory Supplier-PVC infusion bags using 5% glucose or 0.9% NaCl as diluent under ambient conditions.

Key messages

  • What is already known on this subject?

  • 5 Ply Corrugated Card Board Production Machinery(DSP) with 5-HT3receptor antagonists (5-Plastic PVC Fiber Water Hose Pipe Tube Packing Wrapping Machine) in infusion solutions, but the available evidence is not yet conclusive.

  • The use of extemporaneously prepared admixtures of DSP with 5-HDMI Conference Equipment Portable Visual Present with USB.

  • What this study adds?

  • OEM Brass Fitting Air Hose Connector Brass Hose Barb Fittings (male, female, Y type, T type) with Factory Price-HT3receptor antagonists in infusion solutions.

Footnotes

Competing interests:None declared.

Provenance and peer review:Not commissioned; externally peer reviewed.

Data sharing statement:All data from our study are included.

References

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